Publications by authors named "Elliot D Mock"

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Inhibition of endocannabinoid synthesis enzymes DAGL and NAPE-PLD transiently lowers body weight and alters glucose homeostasis during a high-fat diet challenge in mice.
Robin van Eenige, Elena Sánchez-López, Anna T Hoekstra, Zhixiong Ying, Mariëtte R Boon, Elliot D Mock

Eur J Endocrinol· October 2025

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SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides.
Andrea Loreto, Kaitlyn M L Cramb, Lucy A McDermott, Christina Antoniou, Ilenia Cirilli, Elliot D Mock

Neurobiol Dis· September 2025

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Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.
Matthew G Williamson, Marta Madureira, William McGuinness, Rachel Heon-Roberts, Elliot D Mock

Hum Mol Genet· September 2023

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Fluorescence-Based NAPE-PLD Activity Assay.
Elliot D Mock, Wouter P F Driever, Mario van der Stelt

Methods Mol Biol· April 2023

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Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities.
Elliot D Mock, Berend Gagestein, Mario van der Stelt

Prog Lipid Res· January 2023

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Structure-Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of -Acylphosphatidylethanolamine Phospholipase D.
Elliot D Mock, Ioli Kotsogianni, Wouter P F Driever, Carmen S Fonseca, Jelle M Vooijs

J Med Chem· January 2021

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Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family.
Juan Zhou, Elliot D Mock, Karol Al Ayed, Xinyu Di, Vasudev Kantae

J Med Chem· September 2020

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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Elliot D Mock, Mohammed Mustafa, Ozge Gunduz-Cinar, Resat Cinar, Gavin N Petrie

Nat Chem Biol· June 2020

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Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI.
Juan Zhou, Elliot D Mock, Andrea Martella, Vasudev Kantae, Xinyu Di

ACS Chem Biol· February 2019

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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.
Annelot C M van Esbroeck, Antonius P A Janssen, Armand B Cognetta, Daisuke Ogasawara, Guy Shpak, Elliot D Mock

Science· June 2017

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Cannabinoid CB receptor ligand profiling reveals biased signalling and off-target activity.
Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W Grim, Filomena Fezza, Elliot D Mock

Nat Commun· January 2017

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Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib.
Gerjan de Bruin, Elliot D Mock, Sascha Hoogendoorn, Adrianus M C H van den Nieuwendijk, Jaroslaw Mazurek

Chem Commun (Camb)· March 2016

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Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization.
Kristina Oresic Bender, Leslie Ofori, Wouter A van der Linden, Elliot D Mock, Gopal K Datta

J Am Chem Soc· April 2015

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Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites.
Paul P Geurink, Wouter A van der Linden, Anne C Mirabella, Nerea Gallastegui, Gerjan de Bruin, Elliot D Mock

J Med Chem· February 2013

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