Publications by authors named "Emiko Imamura"

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A single amino acid substitution in TAS1R2 defines species-specific sweet sensitivity to sulfamates in humans and mice.
Keisuke Sanematsu, Yuki Nagasato, Yihung Lee, Emiko Imamura, Mami Shinoda

Food Chem· November 2025

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Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potential for cytochrome P450 1A2 induction.
Hiroshi Inami, Tsuyoshi Mizutani, Junko Watanabe, Hisashi Hayashida, Tomonori Ito, Emiko Imamura

Bioorg Med Chem· May 2023

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ASP7266, a Novel Antibody against Human Thymic Stromal Lymphopoietin Receptor for the Treatment of Allergic Diseases.
Mako Numazaki, Masaki Abe, Kaori Hanaoka, Emiko Imamura, Masashi Maeda

J Pharmacol Exp Ther· January 2022

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In vitro pharmacological effects of peficitinib on lymphocyte activation: a potential treatment for systemic sclerosis with JAK inhibitors.
Yukihiro Kitanaga, Emiko Imamura, Yutaka Nakahara, Hidehiko Fukahori, Yasutomo Fujii

Rheumatology (Oxford)· August 2020

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AS2762900-00, a potent anti-human IL-23 receptor monoclonal antibody, prevents epidermal hyperplasia in a psoriatic human skin xenograft model.
Haruna Sasaki-Iwaoka, Katsunari Taguchi, Yohei Okada, Emiko Imamura, Satoshi Kubo

Eur J Pharmacol· January 2019

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Generation and characterization of a potent fully human monoclonal antibody against the interleukin-23 receptor.
Haruna Sasaki-Iwaoka, Makoto Ohori, Akira Imasato, Katsunari Taguchi, Kyoko Minoura, Emiko Imamura

Eur J Pharmacol· June 2018

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Anti-IL-23 receptor monoclonal antibody prevents CD4 T cell-mediated colitis in association with decreased systemic Th1 and Th17 responses.
Emiko Imamura, Katsunari Taguchi, Haruna Sasaki-Iwaoka, Satoshi Kubo, Shigetada Furukawa

Eur J Pharmacol· April 2018

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Defining end-of-life care from perspectives of nursing ethics.
Shigeko Izumi, Hiroko Nagae, Chihoko Sakurai, Emiko Imamura

Nurs Ethics· September 2012

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Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and molecular modeling based on the solved X-ray structure of the beta2-adrenergic receptor: part 6.
Kouji Hattori, Masaya Orita, Susumu Toda, Masashi Imanishi, Shinji Itou, Emiko Imamura

Bioorg Med Chem Lett· August 2009

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Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and evaluation of physical properties as potential overactive bladder therapies: part 5.
Kouji Hattori, Susumu Toda, Masashi Imanishi, Shinji Itou, Yutaka Nakajima, Emiko Imamura

J Med Chem· May 2009

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Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human beta(3)-adrenergic receptor agonists: Part IV.
Yutaka Nakajima, Masashi Imanishi, Shinji Itou, Hitoshi Hamashima, Yasuyo Tomishima, Emiko Imamura

Bioorg Med Chem Lett· September 2008

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Discovery of a novel series of benzoic acid derivatives as potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. 3. Phenylethanolaminotetraline (PEAT) skeleton containing biphenyl or biphenyl ether moiety.
Masashi Imanishi, Yutaka Nakajima, Yasuyo Tomishima, Hitoshi Hamashima, Kenichi Washizuka, Emiko Imamura

J Med Chem· August 2008

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Discovery of a novel series of biphenyl benzoic acid derivatives as highly potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. Part II.
Masashi Imanishi, Shinji Itou, Kenichi Washizuka, Hitoshi Hamashima, Yutaka Nakajima, Emiko Imamura

J Med Chem· July 2008

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Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I.
Masashi Imanishi, Yasuyo Tomishima, Shinji Itou, Hitoshi Hamashima, Yutaka Nakajima, Emiko Imamura

J Med Chem· March 2008

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Discovery of a novel, potent and selective human beta3-adrenergic receptor agonist.
Yutaka Nakajima, Hitoshi Hamashima, Ken-Ichi Washizuka, Yasuyo Tomishima, Hiroaki Ohtake, Emiko Imamura

Bioorg Med Chem Lett· January 2005

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Amy's Chat Room: health promotion programmes for community dwelling elderly adults.
Emiko Imamura

Int J Nurs Pract· February 2002

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