Publications by authors named "Emilio Lecona"

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The SUMO Pathway.
Rodrigo Martín-Rufo, Alicia Gómez-Moya, Emilio Lecona

Methods Mol Biol· August 2025

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DNA polymerase α/primase extraction from chromatin by VCP/p97 restricts ATR activation during unperturbed DNA replication.
Sara Rodríguez-Acebes, Rodrigo Martín-Rufo, Alicia Gómez-Moya, Scott B Churcher, Alejandro Fernández-Llorente, Emilio Lecona

Nat Commun· July 2025

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Ubiquitin and SUMO as timers during DNA replication.
Rodrigo Martín-Rufo, Guillermo de la Vega-Barranco, Emilio Lecona

Semin Cell Dev Biol· December 2022

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USP7 and VCP define the SUMO/Ubiquitin landscape at the DNA replication fork.
André Franz, Pablo Valledor, Patricia Ubieto-Capella, Domenic Pilger, Antonio Galarreta, Emilio Lecona

Cell Rep· October 2021

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Coordinating DNA Replication and Mitosis through Ubiquitin/SUMO and CDK1.
Antonio Galarreta, Pablo Valledor, Oscar Fernandez-Capetillo, Emilio Lecona

Int J Mol Sci· August 2021

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USP7 limits CDK1 activity throughout the cell cycle.
Antonio Galarreta, Pablo Valledor, Patricia Ubieto-Capella, Vanesa Lafarga, Eduardo Zarzuela, Emilio Lecona

EMBO J· June 2021

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SUMOylation modulates the stability and function of PI3K-p110β.
Ahmed El Motiam, Carlos F de la Cruz-Herrera, Santiago Vidal, Rocío Seoane, Maite Baz-Martínez, Emilio Lecona

Cell Mol Life Sci· April 2021

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Targeting ATR in cancer.
Emilio Lecona, Oscar Fernandez-Capetillo

Nat Rev Cancer· September 2018

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ERF deletion rescues RAS deficiency in mouse embryonic stem cells.
Cristina Mayor-Ruiz, Teresa Olbrich, Matthias Drosten, Emilio Lecona, Maria Vega-Sendino

Genes Dev· April 2018

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Correction for Lecona et al., "USP7 Cooperates with SCML2 To Regulate the Activity of PRC1".
Emilio Lecona, Varun Narendra, Danny Reinberg

Mol Cell Biol· October 2017

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Structural and lipid-binding characterization of human annexin A13a reveals strong differences with its long A13b isoform.
Sara Fernández-Lizarbe, Emilio Lecona, Angélica Santiago-Gómez, Nieves Olmo, María Antonia Lizarbe

Biol Chem· March 2017

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A SUMO and ubiquitin code coordinates protein traffic at replication factories.
Emilio Lecona, Oscar Fernandez-Capetillo

Bioessays· December 2016

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POLD3 Is Haploinsufficient for DNA Replication in Mice.
Matilde Murga, Emilio Lecona, Irene Kamileri, Marcos Díaz, Natalia Lugli

Mol Cell· September 2016

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Efficacy of ATR inhibitors as single agents in Ewing sarcoma.
Maria Nieto-Soler, Isabel Morgado-Palacin, Vanesa Lafarga, Emilio Lecona, Matilde Murga

Oncotarget· September 2016

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USP7 is a SUMO deubiquitinase essential for DNA replication.
Emilio Lecona, Sara Rodriguez-Acebes, Julia Specks, Andres J Lopez-Contreras, Isabel Ruppen

Nat Struct Mol Biol· April 2016

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NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Ariana Jacome, Paula Gutierrez-Martinez, Federica Schiavoni, Enrico Tenaglia, Paula Martinez, Emilio Lecona

EMBO J· November 2015

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A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development.
Julia Specks, Emilio Lecona, Andrés J Lopez-Contreras, Oscar Fernandez-Capetillo

Mol Cell Biol· September 2015

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USP7 cooperates with SCML2 to regulate the activity of PRC1.
Emilio Lecona, Varun Narendra, Danny Reinberg

Mol Cell Biol· April 2015

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Replication stress and cancer: it takes two to tango.
Emilio Lecona, Oscar Fernández-Capetillo

Exp Cell Res· November 2014

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Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes.
Roberto Bonasio, Emilio Lecona, Varun Narendra, Philipp Voigt, Fabio Parisi

Elife· July 2014

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Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.
Emilio Lecona, Luis Alejandro Rojas, Roberto Bonasio, Andrew Johnston, Oscar Fernández-Capetillo

PLoS Biol· December 2013

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4F2hc-silencing impairs tumorigenicity of HeLa cells via modulation of galectin-3 and β-catenin signaling, and MMP-2 expression.
Angélica Santiago-Gómez, Juan I Barrasa, Nieves Olmo, Emilio Lecona, Hans Burghardt

Biochim Biophys Acta· September 2013

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Histone deacetylase inhibitors upregulate MMP11 gene expression through Sp1/Smad complexes in human colon adenocarcinoma cells.
Juan I Barrasa, Nieves Olmo, Angélica Santiago-Gómez, Emilio Lecona, Patrick Anglard

Biochim Biophys Acta· February 2012

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Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells.
Juan Ignacio Barrasa, Nieves Olmo, Pablo Pérez-Ramos, Angélica Santiago-Gómez, Emilio Lecona

Apoptosis· October 2011

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MBT domain proteins in development and disease.
Roberto Bonasio, Emilio Lecona, Danny Reinberg

Semin Cell Dev Biol· April 2010

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