Publications by authors named "Matilde Murga"

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Discovery of a novel inhibitor of macropinocytosis with antiviral activity.
Bartlomiej Porebski, Wanda Christ, Alba Corman, Martin Haraldsson, Myriam Barz, Matilde Murga

Mol Ther· September 2024

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SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.
Matilde Murga, Gema Lopez-Pernas, Robert Soliva, Elena Fueyo-Marcos, Corina Amor

Cell Death Dis· September 2024

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Correction: Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression.
Alejo Efeyan, Matilde Murga, Barbara Martinez-Pastor, Ana Ortega-Molina, Rebeca Soria

PLoS One· February 2024

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Emerging concepts in drug discovery for cancer therapy.
Matilde Murga, Oscar Fernandez-Capetillo

Mol Oncol· November 2022

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Activation of the integrated stress response is a vulnerability for multidrug-resistant FBXW7-deficient cells.
Laura Sanchez-Burgos, Belén Navarro-González, Santiago García-Martín, Oleksandra Sirozh, Jorge Mota-Pino, Matilde Murga

EMBO Mol Med· September 2022

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Distinct roles for PARP-1 and PARP-2 in c-Myc-driven B-cell lymphoma in mice.
Miguel A Galindo-Campos, Nura Lutfi, Sarah Bonnin, Carlos Martínez, Talia Velasco-Hernandez, Matilde Murga

Blood· January 2022

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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells.
Teresa Olbrich, Maria Vega-Sendino, Matilde Murga, Guillermo de Carcer, Marcos Malumbres

Cell Rep· July 2019

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BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Dali Zong, Salomé Adam, Yifan Wang, Hiroyuki Sasanuma, Elsa Callén, Matilde Murga

Mol Cell· March 2019

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POLD3 Is Haploinsufficient for DNA Replication in Mice.
Matilde Murga, Emilio Lecona, Irene Kamileri, Marcos Díaz, Natalia Lugli

Mol Cell· September 2016

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Efficacy of ATR inhibitors as single agents in Ewing sarcoma.
Maria Nieto-Soler, Isabel Morgado-Palacin, Vanesa Lafarga, Emilio Lecona, Matilde Murga

Oncotarget· September 2016

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Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.
Isabel Morgado-Palacin, Amanda Day, Matilde Murga, Vanesa Lafarga, Marta Elena Anton

Sci Signal· September 2016

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USP7 is a SUMO deubiquitinase essential for DNA replication.
Emilio Lecona, Sara Rodriguez-Acebes, Julia Specks, Andres J Lopez-Contreras, Isabel Ruppen, Matilde Murga

Nat Struct Mol Biol· April 2016

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A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Sergio Ruiz, Cristina Mayor-Ruiz, Vanesa Lafarga, Matilde Murga, Maria Vega-Sendino

Mol Cell· April 2016

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NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Ariana Jacome, Paula Gutierrez-Martinez, Federica Schiavoni, Enrico Tenaglia, Paula Martinez, Matilde Murga

EMBO J· November 2015

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Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.
Andres J Lopez-Contreras, Julia Specks, Jacqueline H Barlow, Chiara Ambrogio, Claus Desler, Matilde Murga

Genes Dev· April 2015

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INK4a/ARF limits the expansion of cells suffering from replication stress.
Angela Monasor, Matilde Murga, Andres J Lopez-Contreras, Carolina Navas, Gonzalo Gomez

Cell Cycle· June 2013

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A proteomic characterization of factors enriched at nascent DNA molecules.
Andres J Lopez-Contreras, Isabel Ruppen, Maria Nieto-Soler, Matilde Murga, Sara Rodriguez-Acebes

Cell Rep· April 2013

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Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.
David W Schoppy, Ryan L Ragland, Oren Gilad, Nishita Shastri, Ashley A Peters, Matilde Murga

J Clin Invest· January 2012

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Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.
Matilde Murga, Stefano Campaner, Andres J Lopez-Contreras, Luis I Toledo, Rebeca Soria

Nat Struct Mol Biol· November 2011

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Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs.
Luis I Toledo, Matilde Murga, Oscar Fernandez-Capetillo

Mol Oncol· August 2011

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A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.
Luis I Toledo, Matilde Murga, Rafal Zur, Rebeca Soria, Antonio Rodriguez

Nat Struct Mol Biol· June 2011

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ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
Carolyn J McNees, Agueda M Tejera, Paula Martínez, Matilde Murga, Francisca Mulero

J Cell Biol· March 2010

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Cdk2 suppresses cellular senescence induced by the c-myc oncogene.
Stefano Campaner, Mirko Doni, Per Hydbring, Alessandro Verrecchia, Lucia Bianchi, Matilde Murga

Nat Cell Biol· January 2010

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.
Rosa M Marión, Katerina Strati, Han Li, Matilde Murga, Raquel Blanco

Nature· August 2009

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