Publications by authors named "Emily Arner"

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Potentiating cancer immunotherapies with modular albumin-hitchhiking nanobody-STING agonist conjugates.
Blaise R Kimmel, Karan Arora, Neil C Chada, Vijaya Bharti, Alexander J Kwiatkowski, Emily N Arner

Nat Biomed Eng· October 2025

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Mitochondrial fatty acid synthesis and MECR regulate CD4+ T cell function and oxidative metabolism.
KayLee K Steiner, Arissa C Young, Andrew R Patterson, Ayaka Sugiura, McLane J Watson, Emily N Arner

J Immunol· May 2025

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Impaired oxidative phosphorylation drives primary tumor escape and metastasis.
Emily N Arner, Erin Q Jennings, Daniel R Crooks, Christopher J Ricketts, Melissa M Wolf

bioRxiv· January 2025

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AXL-TBK1 driven AKT3 activation promotes metastasis.
Emily N Arner, Dina Alzhanova, Jill M Westcott, Stefan Hinz, Crina Elena Tiron

Sci Signal· December 2024

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Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation.
Nowrin U Chowdhury, Jacqueline-Yvonne Cephus, Emely Henriquez Pilier, Melissa M Wolf, Matthew Z Madden, Emily N Arner

J Clin Invest· October 2024

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Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation.
Darren R Heintzman, Rachael C Sinard, Emilie L Fisher, Xiang Ye, Andrew R Patterson, Emily N Arner

Sci Immunol· September 2024

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Immunometabolism of ferroptosis in the tumor microenvironment.
Gian Luca Lupica-Tondo, Emily N Arner, Denis A Mogilenko, Kelsey Voss

Front Oncol· August 2024

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Author Correction: Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Jackie E Bader, Melissa M Wolf, Gian Luca Lupica-Tondo, Matthew Z Madden, Bradley I Reinfeld, Emily N Arner

Nature· July 2024

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Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism.
KayLee K Steiner, Arissa C Young, Andrew R Patterson, Erin Q Jennings, Channing Chi, Emily N Arner

bioRxiv· July 2024

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Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Jackie E Bader, Melissa M Wolf, Gian Luca Lupica-Tondo, Matthew Z Madden, Bradley I Reinfeld, Emily N Arner

Nature· June 2024

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HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma.
Zachary A Bacigalupa, Emily N Arner, Logan M Vlach, Melissa M Wolf, Whitney A Brown

J Clin Invest· June 2024

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Programable Albumin-Hitchhiking Nanobodies Enhance the Delivery of STING Agonists to Potentiate Cancer Immunotherapy.
John Wilson, Blaise Kimmel, Karan Arora, Neil Chada, Vijaya Bharti, Emily Arner

Res Sq· May 2024

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VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis.
Melissa M Wolf, Matthew Z Madden, Emily N Arner, Jackie E Bader, Xiang Ye

J Clin Invest· April 2024

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Deep Learning-Based H-Score Quantification of Immunohistochemistry-Stained Images.
Zhuoyu Wen, Danni Luo, Shidan Wang, Ruichen Rong, Bret M Evers, Emily N Arner

Mod Pathol· February 2024

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Metabolic programming and immune suppression in the tumor microenvironment.
Emily N Arner, Jeffrey C Rathmell

Cancer Cell· March 2023

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Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.
Kelsey Voss, Allison E Sewell, Evan S Krystofiak, Katherine N Gibson-Corley, Arissa C Young, Emily N Arner

Sci Immunol· January 2023

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Mutation and tissue lineage lead to organ-specific cancer.
Emily N Arner, W Kimryn Rathmell

Nature· June 2022

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AXL Inhibitor TP-0903 Reduces Metastasis and Therapy Resistance in Pancreatic Cancer.
Yuqing Zhang, Emily N Arner, Ali Rizvi, Jason E Toombs, Huocong Huang, Steven L Warner

Mol Cancer Ther· January 2022

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Behind the Wheel of Epithelial Plasticity in KRAS-Driven Cancers.
Emily N Arner, Wenting Du, Rolf A Brekken

Front Oncol· October 2019

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2-Amino-2,3-dihydro-1-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy.
Dongsheng Zhu, Huocong Huang, Daniel M Pinkas, Jinfeng Luo, Debolina Ganguly, Emily Arner

J Med Chem· August 2019

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Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer.
Victoria H Cruz, Emily N Arner, Wenting Du, Alberto E Bremauntz, Rolf A Brekken

JCI Insight· April 2019

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Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.
Victoria H Cruz, Emily N Arner, Katherine W Wynne, Philipp E Scherer, Rolf A Brekken

Mol Metab· October 2018

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Functional Crosstalk between the PP2A and SUMO Pathways Revealed by Analysis of STUbL Suppressor, razor 1-1.
Minghua Nie, Emily Arner, John Prudden, Lana Schaffer, Steven Head

PLoS Genet· July 2016

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