Publications by authors named "Emily Don"

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Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism.
Alison L Hogan, Madison Kane, Patrick Chiu, Grant Richter, Cindy Maurel, Emily K Don

Acta Neuropathol Commun· December 2025

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Critical impact of lysine 136 in TDP-43 phase separation, compartmentalization, and aggregation in living vertebrates.
Cindy Maurel, Natalie M Scherer, Luan Luu, Rowan A Radford, Alison Hogan, Emily K Don

iScience· July 2025

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Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism.
Alison L Hogan, Madison Kane, Patrick Chiu, Grant Richter, Cindy Maurel, Emily K Don

bioRxiv· July 2025

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C9orf72-Associated Dipeptide Repeat Expansions Perturb ER-Golgi Vesicular Trafficking, Inducing Golgi Fragmentation and ER Stress, in ALS/FTD.
Jessica Sultana, Audrey M G Ragagnin, Sonam Parakh, Sayanthooran Saravanabavan, Kai Ying Soo, Emily K Don

Mol Neurobiol· December 2024

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RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo.
Natalie M Scherer, Cindy Maurel, Matthew S Graus, Luke McAlary, Grant Richter, Emily K Don

Nucleic Acids Res· May 2024

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Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3.
Maxinne Watchon, Katherine J Robinson, Luan Luu, Yousun An, Kristy C Yuan, Emily K Don

FASEB J· January 2024

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Microglia morphophysiological diversity and its implications for the CNS.
Andrés Vidal-Itriago, Rowan A W Radford, Jason A Aramideh, Cindy Maurel, Natalie M Scherer, Emily K Don

Front Immunol· November 2022

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Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
Katherine J Robinson, Madelaine C Tym, Alison Hogan, Maxinne Watchon, Kristy C Yuan, Emily K Don

Dis Model Mech· October 2021

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RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish.
Celia Vandestadt, Gilles C Vanwalleghem, Mitra Amiri Khabooshan, Alon M Douek, Hozana Andrade Castillo, Emily Don

Dev Cell· August 2021

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In vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS).
Emily K Don, Alina Maschirow, Rowan A W Radford, Natalie M Scherer, Andrés Vidal-Itriago

Mol Neurobiol· May 2021

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Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations.
Flora Cheng, Alana De Luca, Alison L Hogan, Stephanie L Rayner, Jennilee M Davidson, Emily K Don

Front Mol Neurosci· April 2021

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The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models.
Sonam Parakh, Sina Shadfar, Emma R Perri, Audrey M G Ragagnin, Claudia V Piattoni, Emily K Don

iScience· May 2020

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Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate PASS1 With Zebrafish.
Sheemal S Kumar, Julia I Tandberg, Anahit Penesyan, Liam D H Elbourne, Nadia Suarez-Bosche, Emily Don

Front Cell Infect Microbiol· September 2019

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STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones.
Macarena Pavez, Adrian C Thompson, Hayden J Arnott, Camilla B Mitchell, Ilaria D'Atri, Emily K Don

J Neurosci· June 2019

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Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.
Gloria Castellano-Gonzalez, Kelly R Jacobs, Emily Don, Nicholas J Cole, Seray Adams

Neurotox Res· April 2019

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Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1.
Katherine J Robinson, Kristy C Yuan, Emily K Don, Alison L Hogan, Claire G Winnick

Zebrafish· February 2019

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Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype.
Alison L Hogan, Emily K Don, Stephanie L Rayner, Albert Lee, Angela S Laird

Hum Mol Genet· February 2019

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Aurora kinase B regulates axonal outgrowth and regeneration in the spinal motor neurons of developing zebrafish.
Serene S L Gwee, Rowan A W Radford, Sharron Chow, Monisha D Syal, Marco Morsch, Emily K Don

Cell Mol Life Sci· December 2018

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Neuronal cell culture from transgenic zebrafish models of neurodegenerative disease.
Jamie R Acosta, Maxinne Watchon, Kristy C Yuan, Jennifer A Fifita, Adam J Svahn, Emily K Don

Biol Open· October 2018

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Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo.
Isabel Formella, Adam J Svahn, Rowan A W Radford, Emily K Don, Nicholas J Cole

Redox Biol· October 2018

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Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons.
Adam J Svahn, Emily K Don, Andrew P Badrock, Nicholas J Cole, Manuel B Graeber

Acta Neuropathol· September 2018

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Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.
Albert Lee, Stephanie L Rayner, Serene S L Gwee, Alana De Luca, Hamideh Shahheydari, Emily K Don

Cell Mol Life Sci· January 2018

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Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF complex.
Albert Lee, Stephanie L Rayner, Alana De Luca, Serene S L Gwee, Marco Morsch, Emily K Don

Open Biol· October 2017

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Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype.
Alison L Hogan, Emily K Don, Stephanie L Rayner, Albert Lee, Angela S Laird

Hum Mol Genet· July 2017

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Triggering Cell Stress and Death Using Conventional UV Laser Confocal Microscopy.
Marco Morsch, Rowan A W Radford, Emily K Don, Albert Lee, Elinor Hortle

J Vis Exp· February 2017

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