Publications by authors named "Kelly R Jacobs"

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Systemic perturbations of the kynurenine pathway precede progression to dementia independently of amyloid-β.
Marcela Cespedes, Kelly R Jacobs, Paul Maruff, Alan Rembach, Christopher J Fowler

Neurobiol Dis· September 2022

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Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis.
Amanda L Wright, Paul A Della Gatta, Sheng Le, Britt A Berning, Prachi Mehta, Kelly R Jacobs

Eur J Neurosci· September 2021

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Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans.
Paula Valente-Silva, Igor Cervenka, Duarte M S Ferreira, Jorge C Correia, Sebastian Edman, Kelly R Jacobs

Metabolites· August 2021

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Metabolomic Biomarkers of Multiple Sclerosis: A Systematic Review.
Lachlan Porter, Alireza Shoushtarizadeh, George A Jelinek, Chelsea R Brown, Chai K Lim, Kelly R Jacobs

Front Mol Biosci· December 2020

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Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia.
Jochen Kindler, Chai K Lim, Cynthia Shannon Weickert, Danny Boerrigter, Cherrie Galletly, Kelly R Jacobs

Mol Psychiatry· November 2020

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Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease.
Pratishtha Chatterjee, Henrik Zetterberg, Kathryn Goozee, Chai K Lim, Kelly R Jacobs

J Neuroinflammation· October 2019

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Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau.
Kelly R Jacobs, Chai K Lim, Kaj Blennow, Henrik Zetterberg, Pratishtha Chatterjee

Neurobiol Aging· August 2019

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Microbiota Alterations in Alzheimer's Disease: Involvement of the Kynurenine Pathway and Inflammation.
Michelle L Garcez, Kelly R Jacobs, Gilles J Guillemin

Neurotox Res· August 2019

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Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.
Gloria Castellano-Gonzalez, Kelly R Jacobs, Emily Don, Nicholas J Cole, Seray Adams

Neurotox Res· April 2019

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Inhibiting the kynurenine pathway in spinal cord injury: Multiple therapeutic potentials?
Kelly R Jacobs, David B Lovejoy

Neural Regen Res· December 2018

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Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study.
Pratishtha Chatterjee, Kathryn Goozee, Chai K Lim, Ian James, Kaikai Shen, Kelly R Jacobs

Sci Rep· May 2018

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Major Developments in the Design of Inhibitors along the Kynurenine Pathway.
Kelly R Jacobs, Gloria Castellano-Gonzalez, Gilles J Guillemin, David B Lovejoy

Curr Med Chem· September 2017

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