Publications by authors named "Emily Shacter"

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PDA Biosimilars Workshop Report (September 27-28, 2018)-Getting It Right the First Time for Biosimilar Marketing Applications.
Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Emily Shacter

PDA J Pharm Sci Technol· April 2020

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Taurine chloramine-induced inactivation of cofilin protein through methionine oxidation.
Shen Luo, Hiroshi Uehara, Emily Shacter

Free Radic Biol Med· October 2014

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Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model.
Jennifer S Dickey, Yanira Gonzalez, Baikuntha Aryal, Steven Mog, Asako J Nakamura, Emily Shacter

PLoS One· March 2014

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The iron chelator Dp44mT inhibits the proliferation of cancer cells but fails to protect from doxorubicin-induced cardiotoxicity in spontaneously hypertensive rats.
V Ashutosh Rao, Jun Zhang, Sarah R Klein, Parvaneh Espandiari, Alan Knapton, Emily B Shacter

Cancer Chemother Pharmacol· November 2011

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Chronic inflammation and cancer: the role of the mitochondria.
David W Kamp, Emily Shacter, Sigmund A Weitzman

Oncology (Williston Park)· April 2011

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The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone.
V Ashutosh Rao, Sarah R Klein, Spencer J Bonar, Jacek Zielonka, Naoko Mizuno, Emily Shacter

J Biol Chem· November 2010

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CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer.
Mauro Antonio Alves Castro, Felipe Dal-Pizzol, Stephanie Zdanov, Marcio Soares, Carolina Beatriz Müller, Emily Shacter

Cancer· August 2010

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Importance of cofilin oxidation for oxidant-induced apoptosis.
Stéphanie Zdanov, Fábio Klamt, Emily Shacter

Cell Cycle· May 2010

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Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin.
Fábio Klamt, Stéphanie Zdanov, Rodney L Levine, Ashley Pariser, Yaqin Zhang, Emily Shacter

Nat Cell Biol· October 2009

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The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells.
V Ashutosh Rao, Sarah R Klein, Keli K Agama, Eriko Toyoda, Noritaka Adachi, Emily B Shacter

Cancer Res· February 2009

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Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells.
Hiroshi Uehara, Emily Shacter

J Immunol· February 2008

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The FDA's assessment of follow-on protein products: a historical perspective.
Janet Woodcock, Joseph Griffin, Rachel Behrman, Barry Cherney, Terrie Crescenzi, Emily Shacter

Nat Rev Drug Discov· June 2007

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Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.
Qi Chen, Michael Graham Espey, Andrew Y Sun, Je-Hyuk Lee, Murali C Krishna, Emily Shacter

Proc Natl Acad Sci U S A· May 2007

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Changes to biological source materials.
K Sewerin, Emily Shacter, James Robertson, Claus Wallerius

Biologicals· March 2006

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Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.
Qi Chen, Michael Graham Espey, Murali C Krishna, James B Mitchell, Christopher P Corpe, Emily Shacter

Proc Natl Acad Sci U S A· September 2005

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Desferal inhibits breast tumor growth and does not interfere with the tumoricidal activity of doxorubicin.
Eileen M Hoke, Caroline A Maylock, Emily Shacter

Free Radic Biol Med· August 2005

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Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis.
Baolin Zhang, Yaqin Zhang, Marie-Claire Dagher, Emily Shacter

Cancer Res· July 2005

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Taurine chloramine, an oxidant derived from neutrophils, induces apoptosis in human B lymphoma cells through mitochondrial damage.
Fabio Klamt, Emily Shacter

J Biol Chem· June 2005

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Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model.
Baolin Zhang, Yaqin Zhang, Emily Shacter, Yi Zheng

Biochemistry· February 2005

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Natural anticoagulant proteins in the regulation of autoimmunity: potential role of protein S.
Howard A Anderson, Emily Shacter

Curr Pharm Des· December 2004

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Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.
Baolin Zhang, Yaqin Zhang, Emily Shacter

Mol Cell Biol· July 2004

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Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells.
Baolin Zhang, Yaqin Zhang, Emily Shacter

Mol Cell Biol· August 2003

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Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells.
Howard A Anderson, Caroline A Maylock, Joy A Williams, Cloud P Paweletz, Hongjun Shu, Emily Shacter

Nat Immunol· January 2003

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Distinct modes of cell death induced by different reactive oxygen species: amino acyl chloramines mediate hypochlorous acid-induced apoptosis.
Robert P Englert, Emily Shacter

J Biol Chem· June 2002

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Chronic inflammation and cancer.
Emily Shacter, Sigmund A Weitzman

Oncology (Williston Park)· February 2002

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