Publications by authors named "Alan Knapton"

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Quantitative analysis of underivatized 17 β-estradiol using a high-throughput LC-MS/MS assay - Application to support a pharmacokinetic study in ovariectomized guinea pigs.
Adarsh Gandhi, Murali K Matta, Sharron Stewart, Ashok Chockalingam, Alan Knapton

J Pharm Biomed Anal· January 2020

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Evaluation of a TGN1412 analogue using in vitro assays and two immune humanized mouse models.
Hangyi Yan, Bhagyashree Bhagwat, David Sanden, Aarron Willingham, Alick Tan, Alan D Knapton

Toxicol Appl Pharmacol· June 2019

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Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions.
James L Weaver, Grainne A Tobin, Taylor Ingle, Simona Bancos, David Stevens, Alan Knapton

Part Fibre Toxicol· July 2017

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MicroRNA biomarkers of pancreatic injury in a canine model.
Rodney Rouse, Barry Rosenzweig, Katie Shea, Alan Knapton, Sharron Stewart

Exp Toxicol Pathol· January 2017

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Sex-related differences in mast cell activity and doxorubicin toxicity: a study in spontaneously hypertensive rats.
Jun Zhang, Alan Knapton, Steven E Lipshultz, Thomas R Cochran, Hajime Hiraragi

Toxicol Pathol· September 2014

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Autophagy in pancreatic acinar cells in caerulein-treated mice: immunolocalization of related proteins and their potential as markers of pancreatitis.
Leshuai Zhang, Jun Zhang, Katherine Shea, Lin Xu, Grainne Tobin, Alan Knapton

Toxicol Pathol· September 2014

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Acute effects of nonexcitatory electrical stimulation during systole in isolated cardiac myocytes and perfused heart.
Ksenia Blinova, Jayna Stohlman, Victor Krauthamer, Alan Knapton, Eric Bloomquist

Physiol Rep· August 2014

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The influence of age on serum concentrations of cardiac troponin I: results in rats, monkeys, and commercial sera.
Eugene H Herman, Alan Knapton, Yongmin Liu, Steven E Lipshultz, Joel Estis

Toxicol Pathol· July 2014

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The role of eNOS phosphorylation in causing drug-induced vascular injury.
Grainne A McMahon Tobin, Jun Zhang, David Goodwin, Sharron Stewart, Lin Xu, Alan Knapton

Toxicol Pathol· June 2014

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The utility of serum biomarkers to detect myocardial alterations induced by Imatinib in rats.
Eugene Herman, Alan Knapton, Jun Zhang, Joel Estis, John Todd

Pharmacol Res Perspect· February 2014

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Comparison of the diagnostic accuracy of di-22:6-bis(monoacylglycerol)phosphate and other urinary phospholipids for drug-induced phospholipidosis or tissue injury in the rat.
Karol L Thompson, Kylie Haskins, Barry A Rosenzweig, Sharron Stewart, Jun Zhang, Alan Knapton

Int J Toxicol· June 2012

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A multifaceted evaluation of imatinib-induced cardiotoxicity in the rat.
Eugene H Herman, Alan Knapton, Elliot Rosen, Karol Thompson, Barry Rosenzweig

Toxicol Pathol· December 2011

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The iron chelator Dp44mT inhibits the proliferation of cancer cells but fails to protect from doxorubicin-induced cardiotoxicity in spontaneously hypertensive rats.
V Ashutosh Rao, Jun Zhang, Sarah R Klein, Parvaneh Espandiari, Alan Knapton

Cancer Chemother Pharmacol· November 2011

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Baseline serum cardiac troponin I concentrations in Sprague-Dawley, spontaneous hypertensive, Wistar, Wistar-Kyoto, and Fisher rats as determined with an ultrasensitive immunoassay.
Eugene Herman, Alan Knapton, Elliot Rosen, Jun Zhang, Joel Estis

Toxicol Pathol· June 2011

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Early events in vascular injury in the rat induced by the phosphodiesterase IV inhibitor SCH 351591.
James L Weaver, Jun Zhang, Alan Knapton, Terry Miller, Parvaneh Espandiari

Toxicol Pathol· August 2010

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Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats.
Karol L Thompson, Barry A Rosenzweig, Jun Zhang, Alan D Knapton, Ronald Honchel

Cancer Chemother Pharmacol· July 2010

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Histopathology of vascular injury in Sprague-Dawley rats treated with phosphodiesterase IV inhibitor SCH 351591 or SCH 534385.
Jun Zhang, Ronald D Snyder, Eugene H Herman, Alan Knapton, Ronald Honchel

Toxicol Pathol· October 2008

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Biomarkers in peripheral blood associated with vascular injury in Sprague-Dawley rats treated with the phosphodiesterase IV inhibitors SCH 351591 or SCH 534385.
James L Weaver, Ronald Snyder, Alan Knapton, Eugene H Herman, Ronald Honchel

Toxicol Pathol· October 2008

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Age-related differences in susceptibility to toxic effects of valproic acid in rats.
Parvaneh Espandiari, Jun Zhang, Laura K Schnackenberg, Terry J Miller, Alan Knapton

J Appl Toxicol· July 2008

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Isoproterenol-induced cardiotoxicity in sprague-dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury.
Jun Zhang, Alan Knapton, Steven E Lipshultz, James L Weaver, Eugene H Herman

Toxicol Pathol· February 2008

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The utility of a rodent model in detecting pediatric drug-induced nephrotoxicity.
Parvaneh Espandiari, Jun Zhang, Barry A Rosenzweig, Vishal S Vaidya, Jinchun Sun, Alan Knapton

Toxicol Sci· October 2007

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Serum cardiac troponin T as a biomarker for acute myocardial injury induced by low doses of isoproterenol in rats.
Eugene Herman, Jun Zhang, Alan Knapton, Steven E Lipshultz, Nader Rifai

Cardiovasc Toxicol· April 2007

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Mechanisms and biomarkers of cardiovascular injury induced by phosphodiesterase inhibitor III SK&F 95654 in the spontaneously hypertensive rat.
Jun Zhang, Eugene H Herman, Donald G Robertson, Michael D Reily, Alan Knapton

Toxicol Pathol· August 2006

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Toxicoproteomics: serum proteomic pattern diagnostics for early detection of drug induced cardiac toxicities and cardioprotection.
Emanuel F Petricoin, Vinodh Rajapaske, Eugene H Herman, Ali M Arekani, Sally Ross, Alan Knapton

Toxicol Pathol· October 2004

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SK&F 95654-induced acute cardiovascular toxicity in Sprague-Dawley rats--histopathologic, electron microscopic, and immunohistochemical studies.
Jun Zhang, Eugene H Herman, Alan Knapton, Douglas P Chadwick, Virgil E Whitehurst

Toxicol Pathol· September 2002

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