Publications by authors named "Eugene Herman"

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Development of a pharmaceutical database as an aid to the nonclinical detection of drug-induced cardiac toxicity.
Donald De Alwis, C Michael Foley, Eugene Herman, Adam P Hill, Peter K Hoffmann

J Pharmacol Toxicol Methods· June 2024

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MicroRNA-34a-5p as a promising early circulating preclinical biomarker of doxorubicin-induced chronic cardiotoxicity.
Varsha G Desai, Vikrant Vijay, Taewon Lee, Tao Han, Carrie L Moland, Eugene H Herman

J Appl Toxicol· September 2022

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Spontaneously occurring cardiovascular lesions in commonly used laboratory animals.
Eugene Herman, Sandy Eldridge

Cardiooncology· June 2019

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Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F mice.
Varsha G Desai, Taewon Lee, Carrie L Moland, Vikrant Vijay, Tao Han, Eugene H Herman

Toxicol Appl Pharmacol· January 2019

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Anthracycline cardiotoxicity: the importance of horizontally integrating pre-clinical and clinical research.
Steven E Lipshultz, Eugene H Herman

Cardiovasc Res· February 2018

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Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F mice.
G Ronald Jenkins, Taewon Lee, Carrie L Moland, Vikrant Vijay, Eugene H Herman

Toxicol Appl Pharmacol· November 2016

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Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice.
Vikrant Vijay, Carrie L Moland, Tao Han, James C Fuscoe, Taewon Lee, Eugene H Herman

Toxicol Appl Pharmacol· March 2016

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Early biomarkers of doxorubicin-induced heart injury in a mouse model.
Varsha G Desai, Joshua C Kwekel, Vikrant Vijay, Carrie L Moland, Eugene H Herman

Toxicol Appl Pharmacol· December 2014

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Sex-related differences in mast cell activity and doxorubicin toxicity: a study in spontaneously hypertensive rats.
Jun Zhang, Alan Knapton, Steven E Lipshultz, Thomas R Cochran, Hajime Hiraragi, Eugene H Herman

Toxicol Pathol· September 2014

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The influence of age on serum concentrations of cardiac troponin I: results in rats, monkeys, and commercial sera.
Eugene H Herman, Alan Knapton, Yongmin Liu, Steven E Lipshultz, Joel Estis

Toxicol Pathol· July 2014

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Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model.
Jennifer S Dickey, Yanira Gonzalez, Baikuntha Aryal, Steven Mog, Asako J Nakamura, Eugene Herman

PLoS One· March 2014

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The utility of serum biomarkers to detect myocardial alterations induced by Imatinib in rats.
Eugene Herman, Alan Knapton, Jun Zhang, Joel Estis, John Todd

Pharmacol Res Perspect· February 2014

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Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions: a scientific statement from the American Heart Association.
Steven E Lipshultz, M Jacob Adams, Steven D Colan, Louis S Constine, Eugene H Herman

Circulation· October 2013

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Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model.
Varsha G Desai, Eugene H Herman, Carrie L Moland, William S Branham, Sherry M Lewis

Toxicol Appl Pharmacol· January 2013

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A multifaceted evaluation of imatinib-induced cardiotoxicity in the rat.
Eugene H Herman, Alan Knapton, Elliot Rosen, Karol Thompson, Barry Rosenzweig

Toxicol Pathol· December 2011

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The iron chelator Dp44mT inhibits the proliferation of cancer cells but fails to protect from doxorubicin-induced cardiotoxicity in spontaneously hypertensive rats.
V Ashutosh Rao, Jun Zhang, Sarah R Klein, Parvaneh Espandiari, Alan Knapton, Eugene Herman

Cancer Chemother Pharmacol· November 2011

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Baseline serum cardiac troponin I concentrations in Sprague-Dawley, spontaneous hypertensive, Wistar, Wistar-Kyoto, and Fisher rats as determined with an ultrasensitive immunoassay.
Eugene Herman, Alan Knapton, Elliot Rosen, Jun Zhang, Joel Estis

Toxicol Pathol· June 2011

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Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats.
Karol L Thompson, Barry A Rosenzweig, Jun Zhang, Alan D Knapton, Ronald Honchel, Eugene H Herman

Cancer Chemother Pharmacol· July 2010

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A translational approach to detecting drug-induced cardiac injury with cardiac troponins: consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the Health and Environmental Sciences Institute.
Brian R Berridge, Syril Pettit, Dana B Walker, Alan S Jaffe, Albert E Schultze, Eugene Herman

Am Heart J· July 2009

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Histopathology of vascular injury in Sprague-Dawley rats treated with phosphodiesterase IV inhibitor SCH 351591 or SCH 534385.
Jun Zhang, Ronald D Snyder, Eugene H Herman, Alan Knapton, Ronald Honchel

Toxicol Pathol· October 2008

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Biomarkers in peripheral blood associated with vascular injury in Sprague-Dawley rats treated with the phosphodiesterase IV inhibitors SCH 351591 or SCH 534385.
James L Weaver, Ronald Snyder, Alan Knapton, Eugene H Herman, Ronald Honchel

Toxicol Pathol· October 2008

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Anthracycline cardiotoxicity: from bench to bedside.
Luca Gianni, Eugene H Herman, Steven E Lipshultz, Giorgio Minotti, Narine Sarvazyan

J Clin Oncol· August 2008

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Age-related differences in susceptibility to toxic effects of valproic acid in rats.
Parvaneh Espandiari, Jun Zhang, Laura K Schnackenberg, Terry J Miller, Alan Knapton, Eugene H Herman

J Appl Toxicol· July 2008

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Isoproterenol-induced cardiotoxicity in sprague-dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury.
Jun Zhang, Alan Knapton, Steven E Lipshultz, James L Weaver, Eugene H Herman

Toxicol Pathol· February 2008

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Dexrazoxane: how it works in cardiac and tumor cells. Is it a prodrug or is it a drug?
Brian B Hasinoff, Eugene H Herman

Cardiovasc Toxicol· October 2007

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