Publications by authors named "Emmanuel Contassot"

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Comparison of Acute Generalized Exanthematous Pustulosis with Maculopapular Rash in a Swiss Patient Cohort: A Single-Center Retrospective Study.
Barbara Meier-Schiesser, Fabienne Fröhlich, Dominik Wetzstein, Mirjam C Nägeli, Thomas Kündig, Emmanuel Contassot

Dermatology· October 2025

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Potential Role for IL-33 in the Amplification of CD8 T-Cell-Mediated Cytotoxic Responses in Epidermal Necrolysis.
Sophie Lalevée, Mathieu Surenaud, Mubashira Tariq, Saskia Ingen-Housz-Oro, Francette Jean-Louis, Emmanuel Contassot

J Invest Dermatol· September 2025

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Immune-Related Cutaneous Adverse Events Display Distinct Clinical and Molecular Characteristics, Depending on Immune Checkpoints Targeted.
Lukas Kraehenbuehl, Nicola Winkelbeiner, Patrick Turko, Ramon Staeger, Adhideb Ghosh, Emmanuel Contassot

Cancers (Basel)· June 2025

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MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated Kinase ERK.
Daniel Constantin, Vladimir Nosi, Natalie Kehrer, Alessandro Vacchini, Andrew Chancellor, Emmanuel Contassot

Cancer Immunol Res· October 2024

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Targeting IL-1 controls refractory pityriasis rubra pilaris.
Eloi Schmauch, Yannik Severin, Xianying Xing, Aaron Mangold, Curdin Conrad, Emmanuel Contassot

Sci Adv· July 2024

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Sequential proteomic profiling of patients with Stevens-Johnson syndrome or toxic epidermal necrolysis.
Emmanuel Contassot, Marie-Charlotte Brüggen

Allergy· December 2023

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Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro.
Rishika Agarwal, Tanja Dittmar, Hans-Dietmar Beer, Michael Kunz, Simon Müller, Emmanuel Contassot

Exp Dermatol· July 2023

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Intravenous immunoglobulins, cyclosporine, and best supportive care in epidermal necrolysis: Diverse effects on systemic inflammation.
Veronika Schmidt, Sophie Lalevée, Stephan Traidl, Milad Ameri, Reihane Ziadlou, Emmanuel Contassot

Allergy· May 2023

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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Marianne R Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Emmanuel Contassot

J Clin Invest· February 2023

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Phosphodiesterase-4 Inhibition Reduces Cutaneous Inflammation and IL-1β Expression in a Psoriasiform Mouse Model but Does Not Inhibit Inflammasome Activation.
Barbara Meier-Schiesser, Mark Mellett, Marigdalia K Ramirez-Fort, Julia-Tatjana Maul, Annika Klug, Emmanuel Contassot

Int J Mol Sci· November 2021

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Killing Two Birds with One Stone: TNF Antagonists Downregulate Systemic IL-1β in Psoriasis.
Emmanuel Contassot, Lars E French

J Invest Dermatol· March 2021

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IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes.
Takashi K Satoh, Mark Mellett, Barbara Meier-Schiesser, Gabriele Fenini, Atsushi Otsuka, Emmanuel Contassot

J Clin Invest· March 2020

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Divergent LAG-3 versus BTLA, TIGIT, and FCRL3 expression in Sézary syndrome.
Florian Anzengruber, Desislava Ignatova, Tanja Schlaepfer, Yun-Tsan Chang, Lars E French, Emmanuel Contassot

Leuk Lymphoma· August 2019

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Culprit Drugs Induce Specific IL-36 Overexpression in Acute Generalized Exanthematous Pustulosis.
Barbara Meier-Schiesser, Laurence Feldmeyer, Dragana Jankovic, Mark Mellett, Takashi K Satoh, Emmanuel Contassot

J Invest Dermatol· April 2019

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Genome Editing of Human Primary Keratinocytes by CRISPR/Cas9 Reveals an Essential Role of the NLRP1 Inflammasome in UVB Sensing.
Gabriele Fenini, Serena Grossi, Emmanuel Contassot, Thomas Biedermann, Ernst Reichmann

J Invest Dermatol· December 2018

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Vaccinating against Acne: Benefits and Potential Pitfalls.
Emmanuel Contassot

J Invest Dermatol· November 2018

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CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo.
Mark Mellett, Barbara Meier, Deepa Mohanan, Rebekka Schairer, Phil Cheng, Emmanuel Contassot

J Invest Dermatol· September 2018

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The p38 Mitogen-Activated Protein Kinase Critically Regulates Human Keratinocyte Inflammasome Activation.
Gabriele Fenini, Serena Grossi, Samuel Gehrke, Hans-Dietmar Beer, Takashi K Satoh, Emmanuel Contassot

J Invest Dermatol· June 2018

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Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling.
Deborah S Leuthard, Agathe Duda, Sandra N Freiberger, Sina Weiss, Isabella Dommann, Emmanuel Contassot

J Immunol· May 2018

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Intraperitoneal administration of aluminium-based adjuvants produces severe transient systemic adverse events in mice.
Sandra N Freiberger, Deborah S Leuthard, Agathe Duda, Emmanuel Contassot, Michaela Thallmair

Eur J Pharm Sci· March 2018

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Propionibacterium acnes Strains Differentially Regulate the Fate of Th17 Responses in the Skin.
Emmanuel Contassot, Lars E French

J Invest Dermatol· February 2018

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Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes.
Jennifer Sand, Eric Haertel, Thomas Biedermann, Emmanuel Contassot, Ernst Reichmann

Cell Death Dis· January 2018

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Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.
Gabriele Fenini, Emmanuel Contassot, Lars E French

Front Pharmacol· May 2017

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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Marianne R Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Emmanuel Contassot

J Clin Invest· November 2016

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Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages.
Roman Huber, Barbara Meier, Atsushi Otsuka, Gabriele Fenini, Takashi Satoh, Emmanuel Contassot

Sci Rep· July 2016

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