Publications by authors named "Emmanuel Datan"

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HIF-1-mediated ISG20 expression promotes breast cancer stemness and immune evasion.
Yongkang Yang, Qiaozhu Zuo, Vijay Ramu, Varen Talwar, Yajing Lyu, Emmanuel Datan

J Exp Med· March 2026

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Pharmacologic HIF stabilization activates costimulatory receptor expression to increase antitumor efficacy of adoptive T cell therapy.
Walter Jackson Iii, Yongkang Yang, Shaima Salman, Dominic Dordai, Yajing Lyu, Emmanuel Datan

Sci Adv· August 2024

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Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.
Yajing Lyu, Yongkang Yang, Varen Talwar, Haiquan Lu, Chelsey Chen, Emmanuel Datan

Cell Rep· April 2024

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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis.
Qiaozhu Zuo, Yongkang Yang, Yajing Lyu, Chen Yang, Chelsey Chen, Emmanuel Datan

Cell Rep· March 2023

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NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification.
Yongkang Yang, Chelsey Chen, Qiaozhu Zuo, Haiquan Lu, Shaima Salman, Emmanuel Datan

Sci Adv· December 2022

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HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy.
Shaima Salman, David J Meyers, Elizabeth E Wicks, Sophia N Lee, Emmanuel Datan

J Clin Invest· May 2022

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Autophagic cell death in viral infection: Do TAM receptors play a role?
Emmanuel Datan, Shaima Salman

Int Rev Cell Mol Biol· September 2021

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Triptolide: reflections on two decades of research and prospects for the future.
Lu Tong, Qunfei Zhao, Emmanuel Datan, Guo-Qiang Lin, Il Minn

Nat Prod Rep· April 2021

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A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia.
Emmanuel Datan, Il Minn, Peng Xu, Qing-Li He, Hye-Hyun Ahn

iScience· September 2020

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Atorvastatin restricts the ability of influenza virus to generate lipid droplets and severely suppresses the replication of the virus.
Donna Episcopio, Sarah Aminov, Shawna Benjamin, Gabrielle Germain, Emmanuel Datan

FASEB J· August 2019

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Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation.
Qing-Li He, Il Minn, Qiaoling Wang, Peng Xu, Sarah A Head, Emmanuel Datan

Angew Chem Int Ed Engl· September 2016

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Regulation of cell survival and death during Flavivirus infections.
Sounak Ghosh Roy, Beata Sadigh, Emmanuel Datan, Richard A Lockshin, Zahra Zakeri

World J Biol Chem· May 2014

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mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection.
Emmanuel Datan, Alireza Shirazian, Shawna Benjamin, Demetrius Matassov, Antonella Tinari

Virology· March 2014

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Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication.
Jeffrey E McLean, Aleksandra Wudzinska, Emmanuel Datan, Daniela Quaglino, Zahra Zakeri

J Biol Chem· June 2011

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Lack of Bax prevents influenza A virus-induced apoptosis and causes diminished viral replication.
Jeffrey E McLean, Emmanuel Datan, Demetrius Matassov, Zahra F Zakeri

J Virol· August 2009

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