Publications by authors named "Emmanuelle Braud"

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Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography.
Nicolas Mathas, Emmanuelle Braud, Erwan Galardon, Lucie Larigot, Mélanie Etheve-Quelquejeu

Biochimie· August 2025

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Investigation of a squaramide motif as a bioisostere of the amino-acid group of S-adenosyl-L-methionine and its functional impact on RNA methylation.
Jianxun Du, Batoul Mahcene, Valerii Martynov, Elisa Frezza, Christelle Vasnier, Emmanuelle Braud

Commun Chem· August 2025

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Synthetic approaches to bis-adenosine derivatives as potential bisubstrates of RNA methyltransferases.
Jianxun Du, Bastien Felipe, Dylan Coelho, Laura Iannazzo, Alexandre David, Emmanuelle Braud

Org Biomol Chem· June 2025

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Halo-1,2,3-triazoles: Valuable Compounds to Access Biologically Relevant Molecules.
Dylan Coelho, Yoann Colas, Mélanie Ethève-Quelquejeu, Emmanuelle Braud, Laura Iannazzo

Chembiochem· May 2024

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The catalytic mechanism of the RNA methyltransferase METTL3.
Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi, Jiahua Deng, Dylan Coelho, Emmanuelle Braud

Elife· March 2024

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The catalytic mechanism of the RNA methyltransferase METTL3.
Ivan Corbeski, Pablo Andres Vargas-Rosales, Rajiv Kumar Bedi, Jiahua Deng, Dylan Coelho, Emmanuelle Braud

bioRxiv· December 2023

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Synthesis of Bisubstrate Analogues for RNA Methylation Studies using two Transition-Metal-Catalyzed Reactions.
Dylan Coelho, Laurent Le Corre, Karolina Bartosik, Laura Iannazzo, Emmanuelle Braud

Chemistry· August 2023

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Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis.
Jean-Philippe Barnier, Saidbakhrom Saidjalolov, Flavie Bouchet, Louis Mayer, Zainab Edoo, Emmanuelle Braud

Antimicrob Agents Chemother· September 2022

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Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
Vincent Meynier, Laura Iannazzo, Marjorie Catala, Stephanie Oerum, Emmanuelle Braud

Nucleic Acids Res· June 2022

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Click and Release Chemistry for Activity-Based Purification of β-Lactam Targets.
Saidbakhrom Saidjalolov, Emmanuelle Braud, Zainab Edoo, Laura Iannazzo, Filippo Rusconi

Chemistry· May 2021

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Synthesis of Carbapenems Containing Peptidoglycan Mimetics and Inhibition of the Cross-Linking Activity of a Transpeptidase of l,d Specificity.
Saidbakhrom Saidjalolov, Zainab Edoo, Matthieu Fonvielle, Louis Mayer, Laura Iannazzo, Emmanuelle Braud

Chemistry· February 2021

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Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups.
Colette Atdjian, Dylan Coelho, Laura Iannazzo, Mélanie Ethève-Quelquejeu, Emmanuelle Braud

Molecules· July 2020

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Bisubstrate analogues as structural tools to investigate mA methyltransferase active sites.
Stephanie Oerum, Marjorie Catala, Colette Atdjian, Franck Brachet, Luc Ponchon, Emmanuelle Braud

RNA Biol· June 2019

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Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d-Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis.
Flora Ngadjeua, Emmanuelle Braud, Saidbakhrom Saidjalolov, Laura Iannazzo, Dirk Schnappinger

Chemistry· April 2018

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Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes.
Laura Iannazzo, Matthieu Fonvielle, Emmanuelle Braud, Hubert Hřebabecký, Eliška Procházková

Org Biomol Chem· March 2018

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Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25.
Manal Sarkis, Maria A Miteva, Maria Chiara Dasso Lang, Maryse Jaouen, Marie-Agnès Sari, Emmanuelle Braud

Proteins· April 2017

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Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.
Matthieu Fonvielle, Nicolas Sakkas, Laura Iannazzo, Chloé Le Fournis, Delphine Patin, Emmanuelle Braud

Angew Chem Int Ed Engl· October 2016

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Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC.
Laura Iannazzo, Daria Soroka, Sébastien Triboulet, Matthieu Fonvielle, Fabrice Compain, Emmanuelle Braud

J Med Chem· April 2016

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Synthesis of 3'-fluoro-tRNA analogues for exploring non-ribosomal peptide synthesis in bacteria.
Laura Iannazzo, Guillaume Laisné, Matthieu Fonvielle, Emmanuelle Braud, Jean-Philippe Herbeuval

Chembiochem· February 2015

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Synthesis of 3'-triazoyl-dinucleotides as precursors of stable Phe-tRNA(Phe) and Leu-tRNA(Leu) analogues.
Marco Santarem, Matthieu Fonvielle, Nicolas Sakkas, Guillaume Laisné, Maryline Chemama, Emmanuelle Braud

Bioorg Med Chem Lett· August 2014

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Synthesis and biological evaluation of non-isomerizable analogues of Ala-tRNA(Ala).
Denia Mellal, Matthieu Fonvielle, Marco Santarem, Maryline Chemama, Yoann Schneider, Emmanuelle Braud

Org Biomol Chem· September 2013

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Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition.
Manal Sarkis, Diem Ngan Tran, Stéphanie Kolb, Maria A Miteva, Bruno O Villoutreix, Emmanuelle Braud

Bioorg Med Chem Lett· December 2012

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Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase.
Valérie Lobjois, Carine Froment, Emmanuelle Braud, Fanny Grimal, Odile Burlet-Schiltz

Biochem Biophys Res Commun· June 2011

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5-Substituted [1]pyrindine derivatives with antiproliferative activity.
Stéphanie Kolb, Mary-Lorène Goddard, Ali Loukaci, Odile Mondésert, Bernard Ducommun, Emmanuelle Braud

Eur J Med Chem· March 2010

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Rapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening.
Romain Duval, Stéphanie Kolb, Emmanuelle Braud, David Genest, Christiane Garbay

J Comb Chem· February 2010

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