Publications by authors named "Emre F Bulbul"

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Toward a unified pipeline for natural product discovery: tools and strategies for NRPS and PKS pathway exploration and engineering.
Biyan Chen, Emre F Bülbül, SeoungGun Bang, Hannah A Minas, Kenan A J Bozhüyük

Nat Prod Rep· July 2025

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Engineering the future of medicine: Natural products, synthetic biology and artificial intelligence for next-generation therapeutics.
Emre F Bülbül, Helge B Bode, Steven Schmitt, Kenan A J Bozhüyük

Clin Transl Med· February 2025

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Application of Ligand- and Structure-Based Prediction Models for the Design of Alkylhydrazide-Based HDAC3 Inhibitors as Novel Anti-Cancer Compounds.
Emre F Bülbül, Dina Robaa, Ping Sun, Fereshteh Mahmoudi, Jelena Melesina

Pharmaceuticals (Basel)· July 2023

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Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors.
Stefan Wimmer, Katharina Hoff, Benedikt Martin, Martin Grewer, Laura Denni

Bioorg Chem· February 2023

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Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties.
Ping Sun, Jing Wang, Khadija S Khan, Weiqin Yang, Billy Wai-Lung Ng

J Med Chem· December 2022

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Small Changes Make the Difference for SIRT2: Two Different Binding Modes for 3-Arylmercapto-Acylated Lysine Derivatives.
Diana Kalbas, Marat Meleshin, Sandra Liebscher, Matthes Zessin, Jelena Melesina

Biochemistry· September 2022

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New chromanone derivatives containing thiazoles: Synthesis and antitumor activity evaluation on A549 lung cancer cell line.
Leyla Yurttaş, Halide Edip Temel, Mehmet Onur Aksoy, Emre Fatih Bülbül, Gülşen Akalin Çiftçi

Drug Dev Res· April 2022

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Docking, Binding Free Energy Calculations and In Vitro Characterization of Pyrazine Linked 2-Aminobenzamides as Novel Class I Histone Deacetylase (HDAC) Inhibitors.
Emre F Bülbül, Jelena Melesina, Hany S Ibrahim, Mohamed Abdelsalam, Anita Vecchio

Molecules· April 2022

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Synthesis, biological evaluation, and molecular docking studies of deoxygenated C-glycosides as LpxC inhibitors.
Alexander Dreger, Katharina Hoff, Oriana Agoglitta, Emre F Bülbül, Jelena Melesina

Bioorg Chem· December 2021

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Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
Hany S Ibrahim, Mohamed Abdelsalam, Yanira Zeyn, Matthes Zessin, Al-Hassan M Mustafa

Int J Mol Sci· December 2021

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Strategies To Design Selective Histone Deacetylase Inhibitors.
Jelena Melesina, Conrad V Simoben, Lucas Praetorius, Emre F Bülbül, Dina Robaa

ChemMedChem· May 2021

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Synthesis and biological evaluation of triazolyl-substituted benzyloxyacetohydroxamic acids as LpxC inhibitors.
Katharina Hoff, Sebastian Mielniczuk, Oriana Agoglitta, Maria Teresa Iorio, Manlio Caldara

Bioorg Med Chem· July 2020

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Potent ribonucleotide reductase inhibitors: Thiazole-containing thiosemicarbazone derivatives.
Merve Ertas, Zafer Sahin, Emre F Bulbul, Ceysu Bender, Sevde N Biltekin

Arch Pharm (Weinheim)· November 2019

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Chiral Pool Synthesis, Biological Evaluation and Molecular Docking Studies of C-Furanosidic LpxC Inhibitors.
Alexander Dreger, Omar Kharwb, Oriana Agoglitta, Emre F Bülbül, Jelena Melesina

ChemMedChem· April 2019

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Thiazole-substituted benzoylpiperazine derivatives as acetylcholinesterase inhibitors.
Zafer Sahin, Merve Ertas, Ceysu Bender, Emre F Bülbül, Barkin Berk

Drug Dev Res· December 2018

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