Publications by authors named "Eric A Ertel"

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Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases.
Emmanuel A Meyer, Andrew L Croxford, Carmela Gnerre, Paulina Kulig, Mark J Murphy, Eric A Ertel

J Med Chem· May 2024

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A uniquely efficacious type of CFTR corrector with complementary mode of action.
Valentina Marchesin, Lucile Monnier, Peter Blattmann, Florent Chevillard, Christine Kuntz, Eric A Ertel

Sci Adv· March 2024

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Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies.
Emmanuel A Meyer, Päivi Äänismaa, Eric A Ertel, Eva Hühn, Daniel S Strasser

J Med Chem· March 2023

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Contractions of Human-iPSC-derived Cardiomyocyte Syncytia Measured with a Ca-sensitive Fluorescent Dye in Temperature-controlled 384-well Plates.
Camille Forny, Romain Sube, Eric A Ertel

J Vis Exp· October 2018

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Discovery and evaluation of Ca3.1-selective T-type calcium channel blockers.
Olivier Bezençon, Luboš Remeň, Sylvia Richard, Catherine Roch, Melanie Kessler, Eric A Ertel

Bioorg Med Chem Lett· December 2017

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Discovery and evaluation of Ca3.2-selective T-type calcium channel blockers.
Olivier Bezençon, Luboš Remeň, Sylvia Richard, Catherine Roch, Melanie Kessler, Eric A Ertel

Bioorg Med Chem Lett· December 2017

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Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies.
Olivier Bezençon, Bibia Heidmann, Romain Siegrist, Simon Stamm, Sylvia Richard, Eric A Ertel

J Med Chem· December 2017

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Milestones to the Discovery of T-type Calcium Channel Blockers for the Treatment of Generalized Epilepsies.
Olivier Bezençon, Romain Siegrist, Bibia Heidmann, Davide Pozzi, Simon Stamm, Eric A Ertel

Chimia (Aarau)· October 2017

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Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents.
Philippe Panchaud, Thierry Bruyère, Anne-Catherine Blumstein, Daniel Bur, Alain Chambovey, Eric A Ertel

J Med Chem· May 2017

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Synthesis and Characterization of Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Antibacterial Activity against Gram-Negative Bacteria.
Jean-Philippe Surivet, Cornelia Zumbrunn, Thierry Bruyère, Daniel Bur, Christopher Kohl, Eric A Ertel

J Med Chem· May 2017

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Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T-Type Calcium Channel Blockers.
Lubos Remen, Olivier Bezençon, Lloyd Simons, Rick Gaston, Dennis Downing, Eric A Ertel

J Med Chem· September 2016

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Novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram positive activity and improved safety profile.
Jean-Philippe Surivet, Cornelia Zumbrunn, Georg Rueedi, Daniel Bur, Thierry Bruyère, Eric A Ertel

J Med Chem· January 2015

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Evaluation of the rabbit Purkinje fibre assay as an in vitro tool for assessing the risk of drug-induced torsades de pointes in humans.
Marion Aubert, Rolf Osterwalder, Björn Wagner, Isabelle Parrilla, Icilio Cavero, Eric A Ertel

Drug Saf· January 2007

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