Publications by authors named "Eric A Klein"

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Performance of a Cell-Free DNA-Based Multi-cancer Detection Test in Individuals Presenting With Symptoms Suspicious for Cancers.
Alan H Bryce, David D Thiel, Michael V Seiden, Donald Richards, Ying Luan, Marie Coignet, Quan Zhang, Nan Zhang, Earl Hubbell, Kathryn N Kurtzman

JCO Precis Oncol· July 2023

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The PATHFINDER Study: Assessment of the Implementation of an Investigational Multi-Cancer Early Detection Test into Clinical Practice.
Lincoln D Nadauld, Charles H McDonnell, Tomasz M Beer, Minetta C Liu, Eric A Klein, Andrew Hudnut, Richard A Whittington, Bruce Taylor, Geoffrey R Oxnard, Jafi Lipson

Cancers (Basel)· July 2021

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Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
Eric A Klein, Ian M Thompson, Catherine M Tangen, John J Crowley, M Scott Lucia, Phyllis J Goodman, Lori M Minasian, Leslie G Ford, Howard L Parnes, J Michael Gaziano

October 2011

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Accelerating Drug Development in Hormone-Naïve Prostate Cancer Through Multi-Modal Therapy Strategies: The MetaCURE Phase 2 Randomized Clinical Trial.
Deaglan McHugh, Matthew Dallos, Min Yuen Teo, Sean M McBride, Anuradha Gopalan, Eric A Klein

Clin Cancer Res· November 2025

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Multicancer Early Detection Blood Test Performance in Cancer Survivors From the PATHFINDER Study.
Catherine R Marinac, Elizabeth K O'Donnell, Christina A Clarke, Margarita Lopatin, Eric T Fung, Eric A Klein

JCO Precis Oncol· October 2025

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Clinical Evaluation of Cancer Signal Origin Prediction and Diagnostic Resolution following Multicancer Early Detection Testing in the PATHFINDER Study.
Catherine R Marinac, Charles H McDonnell, Lincoln D Nadauld, Christina A Dilaveri, Robert Reid, Eric A Klein

Cancer Prev Res (Phila)· August 2025

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Low Baseline IsoPSA Index is Associated With a Prolonged Low Risk of Clinically Significant Prostate Cancer Diagnosis in Men With an Elevated PSA.
Nour Abdallah, Rebecca A Campbell, Tarik Benidir, Andrew Wood, Zaeem Lone, Eric A Klein

Urology· July 2025

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Meaningful Work and the Echoes of Time.
Eric A Klein

JAMA· July 2025

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CpgD is a phosphoglycerate cytidylyltransferase required for ceramide diphosphoglycerate synthesis.
Tanisha Dhakephalkar, Ziqiang Guan, Eric A Klein

J Biol Chem· July 2025

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Navigating Complexity: Perspectives on Risk Assessment in the Era of New Blood-Based Tests for Early Cancer Detection.
Christina A Clarke, Breeana L Mitchell, Emma Alme, Jonathan P Beer, Tomasz M Beer, Eric A Klein

Clin Cancer Res· June 2025

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Artificial Intelligence-Based Digital Histologic Classifier for Prostate Cancer Risk Stratification: Independent Blinded Validation in Patients Treated With Radical Prostatectomy.
Magdalena Fay, Ross S Liao, Zaeem M Lone, Chandana A Reddy, Hassan Muhammad, Eric A Klein

JCO Clin Cancer Inform· June 2025

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Modeled Benefit of Individual Cancer Signal Origin Prediction for Multi-Cancer Early Detection.
Eric A Klein, Timothy R Church, Christina A Clarke, Earl Hubbell

Cancer Res Commun· May 2025

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A histidine-rich extension of the mitochondrial F subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria.
Truman Dunkley, Daniel H Shain, Eric A Klein

FEBS Lett· April 2025

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Psychosocial impact associated with a multicancer early detection test (PATHFINDER): a prospective, multicentre, cohort study.
Lincoln Nadauld, Charles H McDonnell, Christina A Dilaveri, Eric A Klein, Robert Reid

Lancet Oncol· February 2025

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Testosterone Replacement Therapy and Risk of COVID-19 and Effect of COVID-19 on Testosterone's Treatment Effect.
Karol M Pencina, A Michael Lincoff, Eric A Klein, Steven E Nissen, Yili Valentine Shang

J Endocr Soc· February 2025

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The genes are important for growth in the presence of sphingosine by promoting sphingosine metabolism.
Pauline DiGianivittorio, Lauren A Hinkel, Jacob R Mackinder, Kristin Schutz, Eric A Klein

Microbiology (Reading)· January 2025

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CpgD is a phosphoglycerate cytidylyltransferase required for ceramide diphosphoglycerate synthesis.
Tanisha Dhakephalkar, Ziqiang Guan, Eric A Klein

bioRxiv· January 2025

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Upgrading of Grade Group 1 Prostate Cancer at Prostatectomy: Germline Risk Factors in a Prospective Cohort.
Michael A Liss, Nicole Zeltser, Yingye Zheng, Camden Lopez, Menghan Liu, Eric A Klein

Cancer Epidemiol Biomarkers Prev· November 2024

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Proposal for an optimised definition of adverse pathology (unfavourable histology) that predicts metastatic risk in prostatic adenocarcinoma independent of grade group and pathological stage.
Jane K Nguyen, Lara R Harik, Eric A Klein, Jianbo Li, Dillon Corrigan

Histopathology· October 2024

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Postprostatectomy Radiotherapy Timing and Long-Term Health-Related Quality of Life.
Sagar A Patel, Dattatraya Patil, Joseph Smith, Christopher S Saigal, Mark S Litwin, Eric A Klein

JAMA Netw Open· October 2024

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The genes are important for growth in the presence of sphingosine by promoting sphingosine metabolism.
Pauline DiGianivittorio, Lauren A Hinkel, Jacob R Mackinder, Kristin Schutz, Eric A Klein

bioRxiv· September 2024

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A Targeted Methylation-Based Multicancer Early Detection Blood Test Preferentially Detects High-Grade Prostate Cancer While Minimizing Overdiagnosis of Indolent Disease.
Brandon A Mahal, Matthew Margolis, Earl Hubbell, Cheng Chen, Jeffrey M Venstrom, Eric A Klein

JCO Precis Oncol· August 2024

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Spatial organization of bacterial sphingolipid synthesis enzymes.
Chioma G Uchendu, Ziqiang Guan, Eric A Klein

J Biol Chem· May 2024

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Genome assembly of sp. strain SED1, a psychrotolerant bacterium isolated from Deception Glacier (Washington, USA).
Daniel H Shain, Eric A Klein

Microbiol Resour Announc· April 2024

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A multi-cancer early detection blood test using machine learning detects early-stage cancers lacking USPSTF-recommended screening.
Janet Vittone, David Gill, Alex Goldsmith, Eric A Klein, Jordan J Karlitz

NPJ Precis Oncol· April 2024

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Editorial Comment.
Eric A Klein

J Urol· March 2024

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Further Discussion Regarding Multicancer Early Detection Tests.
Sana Raoof, Eric A Klein

Am Fam Physician· February 2024

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Intratumoral androgen biosynthesis associated with 3β-hydroxysteroid dehydrogenase 1 promotes resistance to radiotherapy in prostate cancer.
Shinjini Ganguly, Zaeem Lone, Andrew Muskara, Jarrell Imamura, Aimalie Hardaway, Eric A Klein

J Clin Invest· November 2023

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