Publications by authors named "Eric Ballard"

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Gastrointestinal Bleeds Are a Rare Event After Total Hip and Knee Arthroplasty.
Eric T Ballard, Keifer S Bergeson, Samuel J Wisniewski, Sahiba Singh, Sabit Ejub

J Arthroplasty· August 2025

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Comprehensive assessment of drug-drug interactions of the major human metabolite of soticlestat.
Miyuki Ugajin, Mitsuhiro Nishihara, T Eric Ballard, Lawrence Cohen, Bei-Ching Chuang

Xenobiotica· June 2025

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Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P-Glycoprotein Inhibition.
Hongxia Jia, T Eric Ballard, Liming Zhang, Lawrence Cohen, Mackenzie C Bergagnini-Kolev

Clin Pharmacol Drug Dev· May 2025

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Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24-hydroxylase inhibitor soticlestat in healthy volunteers.
Wei Yin, T Eric Ballard, Sean Xiaochun Zhu, Samuel Hsiao, Hao Chen

Br J Clin Pharmacol· February 2024

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The Importance of Tracking "Missing" Metabolites: How and Why?
Shuai Wang, T Eric Ballard, Lisa J Christopher, Robert S Foti, Chungang Gu

J Med Chem· December 2023

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Global elbow instability: a case report.
Jacob Lytle, Amy Meyers, Eric Ballard, Amir-Kianoosh Fallahi, Ryan Nelson

JSES Rev Rep Tech· February 2023

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Gluteus Maximus Tendon Reference: A Novel Method to Restore Leg Length in Total Hip Arthroplasty With Femoral Bone Loss.
Andrew R Ames, Amy L Meyers, Eric T Ballard, Michael J Sorscher

J Am Acad Orthop Surg Glob Res Rev· December 2022

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Pharmacokinetics, mass balance, metabolism, and excretion of the liver-targeted acetyl-CoA carboxylase inhibitor PF-05221304 (clesacostat) in humans.
Tim F Ryder, Arthur Bergman, Amanda King-Ahmad, Neeta B Amin, Manjinder S Lall, T Eric Ballard

Xenobiotica· March 2022

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Simplifying the Execution of HepatoPac MetID Experiments: Metabolite Profile and Intrinsic Clearance Comparisons.
T Eric Ballard, N Kratochwil, Loretta M Cox, Mark A Moen, F Klammers

Drug Metab Dispos· September 2020

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Natural Product Bis-Intercalator Depsipeptides as a New Class of Payloads for Antibody-Drug Conjugates.
Anokha S Ratnayake, Li-Ping Chang, L Nathan Tumey, Frank Loganzo, Joseph A Chemler, T Eric Ballard

Bioconjug Chem· January 2019

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Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
Simon Planken, Douglas C Behenna, Sajiv K Nair, Theodore O Johnson, Asako Nagata, T Eric Ballard

J Med Chem· April 2017

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Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase.
Christina J Crump, Heather E Murrey, T Eric Ballard, Christopher W Am Ende, Xianzhong Wu

ACS Chem Neurosci· August 2016

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Synthesis and Antimicrobial Evaluation of Amixicile-Based Inhibitors of the Pyruvate-Ferredoxin Oxidoreductases of Anaerobic Bacteria and Epsilonproteobacteria.
Andrew J Kennedy, Alexandra M Bruce, Catherine Gineste, T Eric Ballard, Igor N Olekhnovich

Antimicrob Agents Chemother· July 2016

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Determination of Antibody-Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric Interrogation.
Andrew J Bessire, T Eric Ballard, Manoj Charati, Justin Cohen, Michael Green

Bioconjug Chem· July 2016

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Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism.
T Eric Ballard, Shuai Wang, Loretta M Cox, Mark A Moen, Stacy Krzyzewski

Drug Metab Dispos· February 2016

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A tag-free collisionally induced fragmentation approach to detect drug-adducted proteins by mass spectrometry.
T Eric Ballard, Upendra P Dahal, Andrew J Bessire, Richard P Schneider, Kieran F Geoghegan

Rapid Commun Mass Spectrom· November 2015

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Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging.
Heather E Murrey, Joshua C Judkins, Christopher W Am Ende, T Eric Ballard, Yinzhi Fang

J Am Chem Soc· September 2015

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Generation of major human excretory and circulating drug metabolites using a hepatocyte relay method.
T Eric Ballard, Christine C Orozco, R Scott Obach

Drug Metab Dispos· May 2014

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Development of CBAP-BPyne, a probe for γ-secretase and presenilinase.
Natalya Gertsik, T Eric Ballard, Christopher W Am Ende, Douglas S Johnson, Yue-Ming Li

Medchemcomm· March 2014

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An isotopically tagged azobenzene-based cleavable linker for quantitative proteomics.
Yu Qian, Julianne Martell, Nicholas J Pace, T Eric Ballard, Douglas S Johnson

Chembiochem· August 2013

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γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin.
Nikolay Pozdnyakov, Heather E Murrey, Christina J Crump, Martin Pettersson, T Eric Ballard

J Biol Chem· April 2013

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BMS-708,163 targets presenilin and lacks notch-sparing activity.
Christina J Crump, Suita V Castro, Feng Wang, Nikolay Pozdnyakov, T Eric Ballard

Biochemistry· September 2012

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Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model.
Cirle A Warren, Edward van Opstal, T Eric Ballard, Andrew Kennedy, Xia Wang

Antimicrob Agents Chemother· August 2012

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O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors.
Micah J Niphakis, Douglas S Johnson, T Eric Ballard, Cory Stiff, Benjamin F Cravatt

ACS Chem Neurosci· May 2012

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Development of clickable active site-directed photoaffinity probes for γ-secretase.
Christina J Crump, Christopher W am Ende, T Eric Ballard, Nikolay Pozdnyakov, Martin Pettersson

Bioorg Med Chem Lett· April 2012

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