Publications by authors named "Eric Batchelor"

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Pulsed stimuli enable p53 phase resetting to synchronize single cells and modulate cell fate.
Harish Venkatachalapathy, Samuel Dallon, Zhilin Yang, Samira M Azarin, Casim A Sarkar, Eric Batchelor

Mol Syst Biol· April 2025

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Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome.
Subhendu K Das, Sharmistha Karmakar, Harish Venkatachalapathy, Rajiv Kumar Jha, Eric Batchelor

Mol Cell· November 2024

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Inertial effect of cell state velocity on the quiescence-proliferation fate decision.
Harish Venkatachalapathy, Cole Brzakala, Eric Batchelor, Samira M Azarin, Casim A Sarkar

NPJ Syst Biol Appl· October 2024

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Treatment of Sulfur Mustard Corneal Injury by Augmenting the DNA Damage Response (DDR): A Novel Approach.
Robert Shalwitz, Tovah Day, Anna Kotsakis Ruehlmann, Lindsay Julio, Shellaina Gordon, Eric Batchelor

J Pharmacol Exp Ther· January 2024

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Pulsed stimuli entrain p53 to synchronize single cells and modulate cell-fate determination.
Harish Venkatachalapathy, Zhilin Yang, Samira M Azarin, Casim A Sarkar, Eric Batchelor

bioRxiv· November 2023

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YAP localization mediates mechanical adaptation of human cancer cells during extravasation .
Woong Young So, Claudia S Wong, Udochi F Azubuike, Colin D Paul, Paniz Rezvan Sangsari, Eric Batchelor

bioRxiv· November 2023

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Inertial effect of cell state velocity on the quiescence-proliferation fate decision in breast cancer.
Harish Venkatachalapathy, Cole Brzakala, Eric Batchelor, Samira M Azarin, Casim A Sarkar

bioRxiv· May 2023

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Coordination of MAPK and p53 dynamics in the cellular responses to DNA damage and oxidative stress.
Ryan L Hanson, Eric Batchelor

Mol Syst Biol· December 2022

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Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression.
Alexie A Larson, Ahmed S Shams, Shawna L McMillin, Brian P Sullivan, Cha Vue, Eric Batchelor

Am J Physiol Cell Physiol· June 2022

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Progress and challenges in understanding the regulation and function of p53 dynamics.
Zhilin Yang, Ryan L Hanson, Eric Batchelor

Biochem Soc Trans· November 2021

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FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells.
Ying Zheng, Wendy Dubois, Craig Benham, Eric Batchelor, David Levens

Commun Biol· October 2020

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Rucaparib Treatment Alters p53 Oscillations in Single Cells to Enhance DNA-Double-Strand-Break-Induced Cell Cycle Arrest.
Ryan L Hanson, Eric Batchelor

Cell Rep· October 2020

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Dissecting transcriptional amplification by MYC.
Zuqin Nie, Chunhua Guo, Subhendu K Das, Carson C Chow, Eric Batchelor

Elife· July 2020

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p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions.
Marie D Harton, Woo Seuk Koh, Amie D Bunker, Abhyudai Singh, Eric Batchelor

Mol Syst Biol· September 2019

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Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing.
Ryan L Hanson, Joshua R Porter, Eric Batchelor

J Cell Biol· April 2019

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Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations.
Woo Seuk Koh, Joshua R Porter, Eric Batchelor

Sci Rep· April 2019

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NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH Cancer Stem-like Cells.
Carrie D House, Elizabeth Jordan, Lidia Hernandez, Michelle Ozaki, Jana M James, Eric Batchelor

Cancer Res· December 2017

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CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level.
Garmen Yuen, Fehad J Khan, Shaojian Gao, Jayne M Stommel, Eric Batchelor

Nucleic Acids Res· November 2017

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Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response.
Joshua R Porter, Brian E Fisher, Laura Baranello, Julia C Liu, Diane M Kambach, Eric Batchelor

Mol Cell· September 2017

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Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.
Kyong-Rim Kieffer-Kwon, Keisuke Nimura, Suhas S P Rao, Jianliang Xu, Seolkyoung Jung, Eric Batchelor

Mol Cell· August 2017

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Flexible CRISPR library construction using parallel oligonucleotide retrieval.
Abigail Read, Shaojian Gao, Eric Batchelor, Ji Luo

Nucleic Acids Res· June 2017

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Recent progress and open challenges in modeling p53 dynamics in single cells.
Eric Batchelor, Alexander Loewer

Curr Opin Syst Biol· June 2017

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Determining the Limitations and Benefits of Noise in Gene Regulation and Signal Transduction through Single Cell, Microscopy-Based Analysis.
Marie D Harton, Eric Batchelor

J Mol Biol· April 2017

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Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.
Diane M Kambach, Alan S Halim, A Gesine Cauer, Qian Sun, Carlos A Tristan, Eric Batchelor

Oncotarget· February 2017

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Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards.
Joshua R Porter, William G Telford, Eric Batchelor

J Vis Exp· February 2017

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