Publications by authors named "Eric D Eisenmann"

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Drug-drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors.
Jack C Stromatt, Anika T Chowdhury, Kevin M Huang, Shuiying Hu, Alex Sparreboom, Eric D Eisenmann

Expert Rev Clin Pharmacol· December 2025

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Drug-Drug Interaction Liabilities with BTK Inhibitor TL-895.
Jack C Stromatt, Eman A Ahmed, Thomas Drabison, Mahesh R Nepal, Anika T Chowdhury, Eric D Eisenmann

Cancer Res Commun· September 2025

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A Phase 1b/2 Study of TP-0903 and Decitabine Targeting Mutant TP53 and/or Complex Karyotype in Patients with Untreated Acute Myeloid Leukemia ≥Age 60 Years.
Eric D Eisenmann, Ronan Swords, Ying Huang, Shelley Orwick, Daelynn Buelow

Cancer Res Commun· July 2025

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TP53 mutations and TET2 deficiency cooperate to drive leukemogenesis and establish an immunosuppressive environment.
Pu Zhang, Ethan C Whipp, Sarah J Skuli, Mehdi Gharghabi, Caner Saygin, Eric D Eisenmann

J Clin Invest· May 2025

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Resazurin dye is an in vivo sensor of kidney tubular function.
Shirely Acosta Martinez, Isaac Z Karel, Josie A Silvaroli, Eman Ahmed, Ji Young Kim, Eric D Eisenmann

Kidney Int· March 2025

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Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Induced Neuropathy and Mitochondrial Toxicity: Limitations of the Poly-γ Hypothesis and the Potential Roles of Autophagy and Drug Transport.
John Haynes, Arnav Joshi, Ross C Larue, Eric D Eisenmann, Rajgopal Govindarajan

Pharmaceutics· December 2024

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Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen.
Thomas Drabison, Mike Boeckman, Yan Yang, Kevin M Huang, Peter de Bruijn, Eric D Eisenmann

Cancer Res Commun· September 2024

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Darolutamide does not interfere with OATP-mediated uptake of docetaxel.
Stefan A J Buck, Zahra Talebi, Thomas Drabison, Yan Jin, Alice A Gibson, Eric D Eisenmann

Int J Cancer· July 2024

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Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis.
Nadeen Anabtawi, Thomas Drabison, Yan Jin, Eric D Eisenmann, Alex Sparreboom

J Chromatogr B Analyt Technol Biomed Life Sci· July 2024

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Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice.
Yang Li, Yasuhiro Kazuki, Thomas Drabison, Kaoru Kobayashi, Ken-Ichi Fujita, Eric D Eisenmann

Drug Metab Dispos· January 2024

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Unique Cabozantinib Dosing Considerations in People Living with HIV and Cancer.
Eric D Eisenmann, Alex Sparreboom

Clin Cancer Res· December 2023

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Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method.
Zahra Talebi, Dominique A Garrison, Eric D Eisenmann, Kalindi Parmar, Geoffrey I Shapiro

Heliyon· November 2023

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TP-0903 Is Active in Preclinical Models of Acute Myeloid Leukemia with Mutation/Deletion.
Eric D Eisenmann, Jack C Stromatt, Sydney Fobare, Kevin M Huang, Daelynn R Buelow

Cancers (Basel)· December 2022

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Determination of the endogenous OATP1B biomarkers glycochenodeoxycholate-3-sulfate and chenodeoxycholate-24-glucuronide in human and mouse plasma by a validated UHPLC-MS/MS method.
Yan Jin, Yang Li, Eric D Eisenmann, William D Figg, Sharyn D Baker

J Chromatogr B Analyt Technol Biomed Life Sci· November 2022

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Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B.
Dominique A Garrison, Yan Jin, Zahra Talebi, Shuiying Hu, Alex Sparreboom, Eric D Eisenmann

Molecules· October 2022

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BMX kinase mediates gilteritinib resistance in FLT3-mutated AML through microenvironmental factors.
Daelynn R Buelow, Bhavana Bhatnagar, Shelley J Orwick, Jae Yoon Jeon, Eric D Eisenmann

Blood Adv· September 2022

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A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug-Drug Interaction Liabilities.
Yang Li, Yan Jin, Hanieh Taheri, Keith T Schmidt, Alice A Gibson, Eric D Eisenmann

Pharmaceutics· September 2022

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MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.
Muhammad Erfan Uddin, Eric D Eisenmann, Yang Li, Kevin M Huang, Dominique A Garrison

Int J Mol Sci· August 2022

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Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination.
Eric D Eisenmann, Dominique A Garrison, Zahra Talebi, Yan Jin, Josie A Silvaroli

Pharmaceutics· March 2022

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Boosting the oral bioavailability of anticancer drugs through intentional drug-drug interactions.
Eric D Eisenmann, Zahra Talebi, Alex Sparreboom, Sharyn D Baker

Basic Clin Pharmacol Toxicol· January 2022

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Intentional Modulation of Ibrutinib Pharmacokinetics through CYP3A Inhibition.
Eric D Eisenmann, Qiang Fu, Elizabeth M Muhowski, Yan Jin, Muhammad Erfan Uddin

Cancer Res Commun· November 2021

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Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1.
Muhammad Erfan Uddin, Dominique A Garrison, Kyeongmin Kim, Yan Jin, Eric D Eisenmann

Front Pharmacol· March 2021

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Targeting OCT3 attenuates doxorubicin-induced cardiac injury.
Kevin M Huang, Megan Zavorka Thomas, Tarek Magdy, Eric D Eisenmann, Muhammad Erfan Uddin

Proc Natl Acad Sci U S A· February 2021

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TP-0903 is active in models of drug-resistant acute myeloid leukemia.
Jae Yoon Jeon, Daelynn R Buelow, Dominique A Garrison, Mingshan Niu, Eric D Eisenmann

JCI Insight· December 2020

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Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors.
Dominique A Garrison, Zahra Talebi, Eric D Eisenmann, Alex Sparreboom, Sharyn D Baker

Pharmaceutics· September 2020

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