Publications by authors named "Eric D Routh"

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Evaluation of tumor antigen-specific antibody responses in patients with metastatic triple negative breast cancer treated with cyclophosphamide and pembrolizumab.
Eric D Routh, Mark G Woodcock, Wolfgang Beckabir, Steven P Vensko, Jonathan S Serody

J Immunother Cancer· March 2023

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Prognostic attributes of immune signatures in soft tissue sarcomas show differential dependencies on tumor mutational burden.
Shailaja K S Raj, Eric D Routh, Jeff W Chou, Konstantinos I Votanopoulos, Pierre L Triozzi

Cancer· September 2022

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Comprehensive Analysis of the Immunogenomics of Triple-Negative Breast Cancer Brain Metastases From LCCC1419.
Eric D Routh, Amanda E D Van Swearingen, Maria J Sambade, Steven Vensko, Marni B McClure

Front Oncol· July 2022

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Bulk and Single-Cell Profiling of Breast Tumors Identifies TREM-1 as a Dominant Immune Suppressive Marker Associated With Poor Outcomes.
Ashok K Pullikuth, Eric D Routh, Kip D Zimmerman, Julia Chifman, Jeff W Chou

Front Oncol· December 2021

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The RNA helicase DHX36-G4R1 modulates C9orf72 GGGGCC hexanucleotide repeat-associated translation.
Yi-Ju Tseng, Siara N Sandwith, Katelyn M Green, Antonio E Chambers, Amy Krans, Eric D Routh

J Biol Chem· August 2021

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Transcriptomic Features of T Cell-Barren Tumors Are Conserved Across Diverse Tumor Types.
Eric D Routh, Ashok K Pullikuth, Guangxu Jin, Julia Chifman, Jeff W Chou

Front Immunol· March 2021

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G-Quadruplex Helicase DHX36/G4R1 Engages Nuclear Lamina Proteins in Quiescent Breast Cancer Cells.
Adam E Richardson, Zachary A Zentz, Antonio E Chambers, Siara N Sandwith, Michael A Reisinger, Eric D Routh

ACS Omega· September 2020

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Tumor mutational burden is a determinant of immune-mediated survival in breast cancer.
Alexandra Thomas, Eric D Routh, Ashok Pullikuth, Guangxu Jin, Jing Su

Oncoimmunology· July 2018

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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.
Eric D Routh, Steven D Creacy, Peter E Beerbower, Steven A Akman, James P Vaughn

J Vis Exp· March 2017

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Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.
Philip J Smaldino, Eric D Routh, Jung H Kim, Banabihari Giri, Steven D Creacy

PLoS One· May 2016

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G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA.
Banabihari Giri, Philip J Smaldino, Ryan G Thys, Steven D Creacy, Eric D Routh

Nucleic Acids Res· September 2011

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G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates.
Steven D Creacy, Eric D Routh, Fumiko Iwamoto, Yoshikuni Nagamine, Steven A Akman

J Biol Chem· December 2008

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The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates.
James P Vaughn, Steven D Creacy, Eric D Routh, Christi Joyner-Butt, G Scott Jenkins

J Biol Chem· November 2005

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