Publications by authors named "Steven A Akman"

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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.
Eric D Routh, Steven D Creacy, Peter E Beerbower, Steven A Akman, James P Vaughn

J Vis Exp· March 2017

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Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective.
Julia Chifman, Seda Arat, Zhiyong Deng, Erica Lemler, James C Pino, Steven A Akman

PLoS Comput Biol· February 2017

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Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.
Philip J Smaldino, Eric D Routh, Jung H Kim, Banabihari Giri, Steven D Creacy, Steven A Akman

PLoS One· May 2016

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Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.
Jessica Swanner, Jade Mims, David L Carroll, Steven A Akman, Cristina M Furdui

Int J Nanomedicine· April 2016

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Fatty acid metabolites in rapidly proliferating breast cancer.
Joseph T O'Flaherty, Rhonda E Wooten, Michael P Samuel, Michael J Thomas, Edward A Levine, Steven A Akman

PLoS One· December 2013

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Oral paricalcitol (19-nor-1,25-dihydroxyvitamin D2) in women receiving chemotherapy for metastatic breast cancer: a feasibility trial.
Julia A Lawrence, Steven A Akman, Susan A Melin, L Douglas Case, Gary G Schwartz

Cancer Biol Ther· June 2013

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Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27.
Meimei Wan, Weiwei Huang, Timothy E Kute, Lance D Miller, Qiang Zhang, Steven A Akman

Am J Pathol· May 2012

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Mutagenicity of ochratoxin A and its hydroquinone metabolite in the SupF gene of the mutation reporter plasmid Ps189.
Steven A Akman, Marissa Adams, Doug Case, Gyungse Park, Richard A Manderville

Toxins (Basel)· April 2012

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Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1.
Weiwei Huang, Philip J Smaldino, Qiang Zhang, Lance D Miller, Paul Cao, Steven A Akman

Nucleic Acids Res· February 2012

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The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme.
Simon Lattmann, Michael B Stadler, James P Vaughn, Steven A Akman, Yoshikuni Nagamine

Nucleic Acids Res· November 2011

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G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA.
Banabihari Giri, Philip J Smaldino, Ryan G Thys, Steven D Creacy, Eric D Routh, Steven A Akman

Nucleic Acids Res· September 2011

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Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU.
Simon Lattmann, Banabihari Giri, James P Vaughn, Steven A Akman, Yoshikuni Nagamine

Nucleic Acids Res· October 2010

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G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates.
Steven D Creacy, Eric D Routh, Fumiko Iwamoto, Yoshikuni Nagamine, Steven A Akman

J Biol Chem· December 2008

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Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.
Tasha R Smith, Edward A Levine, Rita I Freimanis, Steven A Akman, Glenn O Allen

Carcinogenesis· November 2008

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Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin.
Ewa Gajewski, Shikha Gaur, Steven A Akman, Linda Matsumoto, Josephus N A van Balgooy

Biochem Pharmacol· June 2007

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Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli.
Dana C Upton, Xueying Wang, Patrick Blans, Fred W Perrino, James C Fishbein, Steven A Akman

Mutat Res· July 2006

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Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293.
Dana C Upton, Xueying Wang, Patrick Blans, Fred W Perrino, James C Fishbein, Steven A Akman

Chem Res Toxicol· July 2006

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The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates.
James P Vaughn, Steven D Creacy, Eric D Routh, Christi Joyner-Butt, G Scott Jenkins, Steven A Akman

J Biol Chem· November 2005

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The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner.
Lori S Hart, Steven M Yannone, Christine Naczki, Joseph S Orlando, Stephen B Waters, Steven A Akman

J Biol Chem· January 2005

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The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha.
Fred W Perrino, Patrick Blans, Scott Harvey, Stacy L Gelhaus, Colleen McGrath, Steven A Akman

Chem Res Toxicol· December 2003

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Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A.
Richard A Manderville, M Wade Calcutt, Jian Dai, Gyungse Park, Ivan G Gillman, Steven A Akman

J Inorg Biochem· June 2003

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Detection and characterization of a glutathione conjugate of ochratoxin A.
Jian Dai, Gyungse Park, Marcus W Wright, Marissa Adams, Steven A Akman

Chem Res Toxicol· December 2002

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