Publications by authors named "Eric Diffenderfer"

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Deliverable proton conformal FLASH radiotherapy treatment planning for head and neck re-irradiation patients.
Wei Zou, Lei Dong, Arnaud Pin, Rasmus Nilsson, Michele Kim, Eric Diffenderfer

Radiother Oncol· December 2025

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Advancing Proton FLASH Radiation Therapy: Innovations, Techniques, and Clinical Potentials.
Yangguang Ma, Tengda Zhang, Balaji Selvaraj, Jiajian Shen, Shouyi Wei, Eric Diffenderfer

Int J Radiat Oncol Biol Phys· November 2025

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First multi-institutional systematic comparison of the neutron ambient dose equivalent produced by proton therapy systems.
Arash Darafsheh, Yao Hao, Anissa Bey, Michele M Kim, Eric S Diffenderfer

Phys Med Biol· November 2025

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Experimental validation of coarse ridge filters for FLASH proton therapy.
Lucian Hotoiu, Francois Vander Stappen, Arnaud Pin, Rasmus Nilsson, Justin Ivoc, Eric Diffenderfer

Med Phys· September 2025

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Physicochemical indication of the FLASH effect from shoot-through proton pencil beam scanning parameters delivered under ultra-high dose rates.
Andrew M Friberg, Hai Siong Tan, Eric S Diffenderfer, Ioannis Verginadis, Michele M Kim

Phys Med Biol· August 2025

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Verification of dose and dose rate for quality assurance of spread-out-Bragg-peak proton FLASH radiotherapy using machine log files.
Seyyedeh Azar Oliaei Motlagh, François Vander Stappen, Michele M Kim, Rudi Labarbe, Lucian Hotoiu, Eric S Diffenderfer

Med Phys· June 2025

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Proton Beam Therapy for Pancreatic Tumors: A Consensus Statement from the Particle Therapy Cooperative Group Gastrointestinal Subcommittee.
Arpit M Chhabra, Richard A Amos, Charles B Simone, Adeel Kaiser, Luis A Perles, Eric S Diffenderfer

Int J Radiat Oncol Biol Phys· May 2025

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FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone.
Ioannis I Verginadis, Anastasia Velalopoulou, Michele M Kim, Kyle Kim, Ioannis Paraskevaidis, Eric S Diffenderfer

Radiother Oncol· April 2025

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Cardiorespiratory-gated cardiac proton radiotherapy using a novel ultrasound guidance system.
Keith A Cengel, Zayne Belal, Michele M Kim, Sarah Hagan, Saskia Camps, Eric Diffenderfer

Clin Transl Radiat Oncol· March 2025

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FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy.
Haiwei Ni, Zachary J Reitman, Wei Zou, Md Naushad Akhtar, Ritama Paul, Eric S Diffenderfer

Nat Cancer· March 2025

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Self-organization of the hematopoietic vascular niche and emergent innate immunity on a chip.
Andrei Georgescu, Joseph Hai Oved, Jonathan H Galarraga, Thomas Cantrell, Samira Mehta, Eric S Diffenderfer

Cell Stem Cell· December 2024

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FLASH Proton Radiation Therapy Mitigates Inflammatory and Fibrotic Pathways and Preserves Cardiac Function in a Preclinical Mouse Model of Radiation-Induced Heart Disease.
Kyle Kim, Michele M Kim, Giorgos Skoufos, Eric S Diffenderfer, Seyyedeh Azar Oliaei Motlagh

Int J Radiat Oncol Biol Phys· July 2024

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Secondary neutron dosimetry for conformal FLASH proton therapy.
Dixin Chen, Seyyedeh Azar Oliaei Motlagh, François Vander Stappen, Rudi Labarbe, Beryl Bell, Eric Stanton Diffenderfer

Med Phys· July 2024

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FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone.
Ioannis I Verginadis, Anastasia Velalopoulou, Michele M Kim, Kyle Kim, Ioannis Paraskevaidis, Eric S Diffenderfer

bioRxiv· July 2024

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Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.
Uri Amit, Ugur Uslu, Ioannis I Verginadis, Michele M Kim, Seyyedeh Azar Oliaei Motlagh, Eric S Diffenderfer

Proc Natl Acad Sci U S A· July 2024

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Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer.
Priyanka Chowdhury, Anastasia Velalopoulou, Ioannis I Verginadis, George Morcos, Phoebe E Loo, Eric S Diffenderfer

Mol Cancer Ther· June 2024

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FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?
Keith A Cengel, Michele M Kim, Eric S Diffenderfer, Theresa M Busch

Semin Radiat Oncol· April 2024

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One-year outcomes after stereotactic body radiotherapy for refractory ventricular tachycardia.
Jeffrey Arkles, Tim Markman, Rachel Trevillian, Nikhil Yegya-Raman, Lohit Garg, Eric Diffenderfer

Heart Rhythm· January 2024

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Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients.
Antonia Rotolo, Eoin C Whelan, Matthew J Atherton, Irina Kulikovskaya, Danuta Jarocha, Eric S Diffenderfer

Cell Rep Med· October 2023

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Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps.
Wei Zou, Rongxiao Zhang, Emil Schüler, Paige A Taylor, Anthony E Mascia, Eric S Diffenderfer

Int J Radiat Oncol Biol Phys· August 2023

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Modeling ultra-high dose rate electron and proton FLASH effect with the physicochemical approach.
Hai Siong Tan, Kevin Boon Keng Teo, Lei Dong, Andrew Friberg, Constantinos Koumenis, Eric Diffenderfer

Phys Med Biol· July 2023

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A phenomenological model of proton FLASH oxygen depletion effects depending on tissue vasculature and oxygen supply.
Wei Zou, Haram Kim, Eric S Diffenderfer, David J Carlson, Cameron J Koch

Front Oncol· November 2022

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Oxygen Monitoring in Model Solutions and In Vivo in Mice During Proton Irradiation at Conventional and FLASH Dose Rates.
Alexander L Van Slyke, Mirna El Khatib, Anastasia Velalopoulou, Eric Diffenderfer, Khayrullo Shoniyozov

Radiat Res· August 2022

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Ultrafast Tracking of Oxygen Dynamics During Proton FLASH.
Mirna El Khatib, Alexander L Van Slyke, Anastasia Velalopoulou, Michele M Kim, Khayrullo Shoniyozov, Eric E Diffenderfer

Int J Radiat Oncol Biol Phys· July 2022

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Radiomic Phenotypes for Improving Early Prediction of Survival in Stage III Non-Small Cell Lung Cancer Adenocarcinoma after Chemoradiation.
José Marcio Luna, Andrew R Barsky, Russell T Shinohara, Leonid Roshkovan, Michelle Hershman, Eric S Diffenderfer

Cancers (Basel)· January 2022

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