Publications by authors named "Eric J Drake"

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Structural and functional delineation of aerobactin biosynthesis in hypervirulent .
Daniel C Bailey, Evan Alexander, Matthew R Rice, Eric J Drake, Lisa S Mydy

J Biol Chem· May 2018

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Substrate Trapping in the Siderophore Tailoring Enzyme PvdQ.
Kenneth D Clevenger, Romila Mascarenhas, Daniel Catlin, Rui Wu, Neil L Kelleher, Eric J Drake

ACS Chem Biol· March 2017

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Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture.
Bradley R Miller, Eric J Drake, Ce Shi, Courtney C Aldrich, Andrew M Gulick

J Biol Chem· October 2016

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Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae.
Daniel C Bailey, Eric J Drake, Thomas D Grant, Andrew M Gulick

Biochemistry· June 2016

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1.2 Å resolution crystal structure of the periplasmic aminotransferase PvdN from Pseudomonas aeruginosa.
Eric J Drake, Andrew M Gulick

Acta Crystallogr F Struct Biol Commun· May 2016

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Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase.
John P Richard, Tina L Amyes, M Merced Malabanan, Xiang Zhai, Kalvin J Kim, Eric J Drake

Biochemistry· May 2016

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Structures of two distinct conformations of holo-non-ribosomal peptide synthetases.
Eric J Drake, Bradley R Miller, Ce Shi, Jeffrey T Tarrasch, Jesse A Sundlov

Nature· January 2016

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Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases.
Bradley R Miller, Jesse A Sundlov, Eric J Drake, Thomas A Makin, Andrew M Gulick

Proteins· October 2014

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Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine.
Jacqueline M Wurst, Eric J Drake, Jimmy R Theriault, Ivan T Jewett, Lynn VerPlank

ACS Chem Biol· July 2014

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Aerobactin mediates virulence and accounts for increased siderophore production under iron-limiting conditions by hypervirulent (hypermucoviscous) Klebsiella pneumoniae.
Thomas A Russo, Ruth Olson, Ulrike Macdonald, Daniel Metzger, Lauren M Maltese, Eric J Drake

Infect Immun· June 2014

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Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate.
Daniel Demonte, Eric J Drake, Kok Hong Lim, Andrew M Gulick, Sheldon Park

Proteins· September 2013

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Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.
João Neres, Curtis A Engelhart, Eric J Drake, Daniel J Wilson, Peng Fu

J Med Chem· March 2013

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Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors.
Avinash Muppidi, Kenichiro Doi, Selvakumar Edwardraja, Eric J Drake, Andrew M Gulick

J Am Chem Soc· September 2012

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Structural characterization and high-throughput screening of inhibitors of PvdQ, an NTN hydrolase involved in pyoverdine synthesis.
Eric J Drake, Andrew M Gulick

ACS Chem Biol· November 2011

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Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis.
Eric J Drake, Benjamin P Duckworth, João Neres, Courtney C Aldrich, Andrew M Gulick

Biochemistry· November 2010

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Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin.
Eric J Drake, Andrew M Gulick

J Mol Biol· December 2008

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The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa.
Eric J Drake, Jin Cao, Jun Qu, Manish B Shah, Robert M Straubinger

J Biol Chem· July 2007

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Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli.
Jesse A Sundlov, Julie A Garringer, Jill M Carney, Albert S Reger, Eric J Drake

Acta Crystallogr D Biol Crystallogr· July 2006

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Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.
Eric J Drake, David A Nicolai, Andrew M Gulick

Chem Biol· April 2006

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