Publications by authors named "Eric L Moore"

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Invention of novel 3-aminopiperidin-2-ones as calcitonin gene-related peptide receptor antagonists.
Donnette D Staas, Ian M Bell, Christopher S Burgey, James Z Deng, Steven N Gallicchio, Eric L Moore

Bioorg Med Chem Lett· November 2024

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Structural basis for selectivity and diversity in angiotensin II receptors.
Haitao Zhang, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L White, Eric L Moore

Nature· April 2017

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Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraine.
Brendan M Crowley, Craig A Stump, Diem N Nguyen, Craig M Potteiger, Melody A McWherter, Eric L Moore

Bioorg Med Chem Lett· November 2015

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(E)-Alkenes as replacements of amide bonds: development of novel and potent acyclic CGRP receptor antagonists.
June J Kim, Michael R Wood, Shawn J Stachel, Pablo de Leon, Ashley Nomland, Eric L Moore

Bioorg Med Chem Lett· January 2014

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[(11)C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor.
Ian M Bell, Steven N Gallicchio, Craig A Stump, Joseph G Bruno, Hong Fan, Eric L Moore

ACS Med Chem Lett· September 2013

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MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.
Ian M Bell, Craig A Stump, Steven N Gallicchio, Donnette D Staas, C Blair Zartman, Eric L Moore

Bioorg Med Chem Lett· June 2012

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Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.
Eric L Moore, Christopher A Salvatore

Br J Pharmacol· May 2012

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Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chirality.
Michael R Wood, Kathy M Schirripa, June J Kim, Rodney A Bednar, John F Fay, Eric L Moore

Bioorg Med Chem Lett· November 2010

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Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist.
Christopher A Salvatore, Eric L Moore, Amy Calamari, Jacquelynn J Cook, Maria S Michener

J Pharmacol Exp Ther· April 2010

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Identification of potent, highly constrained CGRP receptor antagonists.
Craig A Stump, Ian M Bell, Rodney A Bednar, John F Fay, Steven N Gallicchio, Eric L Moore

Bioorg Med Chem Lett· April 2010

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Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist.
Ian M Bell, Steven N Gallicchio, Michael R Wood, Amy G Quigley, Craig A Stump, Eric L Moore

ACS Med Chem Lett· April 2010

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Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility.
Michael R Wood, Kathy M Schirripa, June J Kim, Amy G Quigley, Craig A Stump, Eric L Moore

Bioorg Med Chem Lett· October 2009

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The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.
Ian M Bell, Rodney A Bednar, Halea A Corcoran, John F Fay, Steven N Gallicchio, Eric L Moore

Bioorg Med Chem Lett· August 2009

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The discovery of highly potent CGRP receptor antagonists.
Craig A Stump, Ian M Bell, Rodney A Bednar, Joseph G Bruno, John F Fay, Eric L Moore

Bioorg Med Chem Lett· January 2009

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Examining the binding properties of MK-0974: a CGRP receptor antagonist for the acute treatment of migraine.
Eric L Moore, Christopher S Burgey, Daniel V Paone, Anthony W Shaw, Yui S Tang

Eur J Pharmacol· January 2009

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HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity.
Samer R Eid, Eric D Crown, Eric L Moore, Hongyu A Liang, Kar-Chan Choong

Mol Pain· October 2008

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Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine.
Christopher A Salvatore, James C Hershey, Halea A Corcoran, John F Fay, Victor K Johnston, Eric L Moore

J Pharmacol Exp Ther· February 2008

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Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonists.
Ian M Bell, Rodney A Bednar, John F Fay, Steven N Gallicchio, Jerome H Hochman, Eric L Moore

Bioorg Med Chem Lett· December 2006

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