Publications by authors named "Eric Lachacz"

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Development of production methodologies for scFv-Fc conjugated critical reagents to support CAR-T clinical programs.
Ellen O'Connor, Eric Lachacz, Jared Delmar, Bradley D'souza, Samuel Edwards

Bioanalysis· November 2025

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Clinical evidence of immunogenicity of CAR-T cell therapies and its implication in the clinical development of CAR-T drug products.
Hammodah R Alfar, Cecil Chen, Eric Lachacz, Weifeng Tang, Yuqian Zhang

Front Immunol· May 2025

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High-sensitivity quantification of antisense oligonucleotides for pharmacokinetic characterization.
Shilpi Mahajan, Hui Zhao, Kristina Kovacina, Eric Lachacz, Sany Hoxha

Bioanalysis· May 2022

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Insights into the modular design of kinase inhibitors and application to Abl and Axl.
Sameer Phadke, Lluis Lopez-Barcons, Nathalie Vandecan, Zhifen Wu, Taylor K Johnson, Eric J Lachacz

RSC Med Chem· January 2022

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Retraction: UM-164: A Potent c-Src/p38 Kinase Inhibitor with Activity against Triple-Negative Breast Cancer.
Rabia A Gilani, Sameer Phadke, Li Wei Bao, Eric J Lachacz, Michele L Dziubinski

Clin Cancer Res· April 2020

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Molecular determinants of drug response in TNBC cell lines.
Nathan M Merrill, Eric J Lachacz, Nathalie M Vandecan, Peter J Ulintz, Liwei Bao

Breast Cancer Res Treat· January 2020

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Selective Proteolysis to Study the Global Conformation and Regulatory Mechanisms of c-Src Kinase.
Michael P Agius, Kristin S Ko, Taylor K Johnson, Frank E Kwarcinski, Sameer Phadke, Eric J Lachacz

ACS Chem Biol· July 2019

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UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer.
Rabia A Gilani, Sameer Phadke, Li Wei Bao, Eric J Lachacz, Michele L Dziubinski

Clin Cancer Res· October 2016

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Synthesis and Biological Evaluation of Lactimidomycin and Its Analogues.
Brian J Larsen, Zhankui Sun, Eric Lachacz, Yaroslav Khomutnyk, Matthew B Soellner

Chemistry· December 2015

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Exquisitely specific bisubstrate inhibitors of c-Src kinase.
Kristoffer R Brandvold, Shana M Santos, Meghan E Breen, Eric J Lachacz, Michael E Steffey

ACS Chem Biol· June 2015

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Substrate activity screening with kinases: discovery of small-molecule substrate-competitive c-Src inhibitors.
Meghan E Breen, Michael E Steffey, Eric J Lachacz, Frank E Kwarcinski, Christel C Fox

Angew Chem Int Ed Engl· July 2014

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