Publications by authors named "Eric Perkey"

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Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation.
Dave Maurice De Sousa, Eric Perkey, Laure Le Corre, Salix Boulet, Daniela Gómez Atria

J Exp Med· May 2025

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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs.
Anneka Allman, Brian T Gaudette, Samantha Kelly, Nagham Alouche, Léolène J Carrington, Eric Perkey

Immunity· January 2025

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DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance.
Nan Zhou, Jaewoo Choi, Grant Grothusen, Bang-Jin Kim, Diqiu Ren, Eric Perkey

Blood· September 2023

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Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates.
Victor Tkachev, Ashley Vanderbeck, Eric Perkey, Scott N Furlan, Connor McGuckin

Sci Transl Med· June 2023

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Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells.
Daniela Gómez Atria, Brian T Gaudette, Jennifer Londregan, Samantha Kelly, Eric Perkey

J Clin Invest· July 2022

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Zinc: a damage signal promoting thymic repair.
Eric Perkey, Ivan Maillard

Blood· June 2022

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A Murine Model of X-Linked Moesin-Associated Immunodeficiency (X-MAID) Reveals Defects in T Cell Homeostasis and Migration.
Lyndsay Avery, Tanner F Robertson, Christine F Wu, Nathan H Roy, Samuel D Chauvin, Eric Perkey

Front Immunol· February 2022

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Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline.
Jacqueline V Graniel, Kamlesh Bisht, Ann Friedman, James White, Eric Perkey

Life Sci Alliance· January 2022

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Acetylcholine-synthesizing macrophages in subcutaneous fat are regulated by β -adrenergic signaling.
Alexander J Knights, Shanshan Liu, Yingxu Ma, Victoria S Nudell, Eric Perkey

EMBO J· December 2021

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TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis.
Sherilyn Grill, Shilpa Padmanaban, Ann Friedman, Eric Perkey, Frederick Allen

JCI Insight· May 2021

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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies.
Kevin R Parker, Denis Migliorini, Eric Perkey, Kathryn E Yost, Aparna Bhaduri

Cell· October 2020

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GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.
Eric Perkey, Dave Maurice De Sousa, Léolène Carrington, Jooho Chung, Alexander Dils

J Immunol· March 2020

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Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.
Szymon Klossowski, Hongzhi Miao, Katarzyna Kempinska, Tao Wu, Trupta Purohit, Eric Perkey

J Clin Invest· February 2020

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Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4 T Cells in Graft-versus-Host Disease.
Jooho Chung, Vedran Radojcic, Eric Perkey, Timothy J Parnell, Yashar Niknafs

J Immunol· July 2019

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Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.
Vedran Radojcic, Katelyn Paz, Jooho Chung, Jing Du, Eric T Perkey

Blood· November 2018

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An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling.
Heejin Jun, Hui Yu, Jianke Gong, Juan Jiang, Xiaona Qiao, Eric Perkey

Nat Med· June 2018

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New Insights into Graft-Versus-Host Disease and Graft Rejection.
Eric Perkey, Ivan Maillard

Annu Rev Pathol· January 2018

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BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells.
Ester Valls, Camille Lobry, Huimin Geng, Ling Wang, Mariano Cardenas, Eric Perkey

Cancer Discov· May 2017

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Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Jooho Chung, Christen L Ebens, Eric Perkey, Vedran Radojcic, Ute Koch

J Clin Invest· April 2017

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Increased mammalian target of rapamycin complex 2 signaling promotes age-related decline in CD4 T cell signaling and function.
Eric Perkey, Diane Fingar, Richard A Miller, Gonzalo G Garcia

J Immunol· November 2013

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Ex vivo enzymatic treatment of aged CD4 T cells restores cognate T cell helper function and enhances antibody production in mice.
Eric Perkey, Richard A Miller, Gonzalo G Garcia

J Immunol· December 2012

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