Publications by authors named "Eric Petitclerc"

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C5a receptor antagonism coming of age for vascular pathology.
François Marceau, Eric Petitclerc

Int Immunopharmacol· September 2022

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Ultra-small gadolinium oxide nanoparticles to image brain cancer cells in vivo with MRI.
Luc Faucher, Andrée-Anne Guay-Bégin, Jean Lagueux, Marie-France Côté, Eric Petitclerc

Contrast Media Mol Imaging· January 2012

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Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships.
Sébastien Fortin, Lianhu Wei, Emmanuel Moreau, Jacques Lacroix, Marie-France Côté, Eric Petitclerc

Eur J Med Chem· November 2011

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Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4.
Sébastien Fortin, Lianhu Wei, Emmanuel Moreau, Jacques Lacroix, Marie-France Côté, Eric Petitclerc

J Med Chem· July 2011

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ASK1-P38 pathway is important for anoikis induced by microtubule-targeting aryl chloroethylureas.
Jessica Fortin, Alexandre Patenaude, Réna G Deschesnes, Marie-France Côté, Eric Petitclerc

J Pharm Pharm Sci· December 2010

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Vascular smooth muscle contractility assays for inflammatory and immunological mediators.
François Marceau, Denis deBlois, Eric Petitclerc, Luc Levesque, Guy Drapeau

Int Immunopharmacol· November 2010

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Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation.
Alexandre Patenaude, Jessica S Fortin, Réna Deschenes, Marie-France Côté, Jacques Lacroix, Eric Petitclerc

Can J Physiol Pharmacol· November 2010

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Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N'-(2-chloroethyl)ureas.
Sébastien Fortin, Emmanuel Moreau, Jacques Lacroix, Marie-France Côté, Eric Petitclerc

Eur J Med Chem· July 2010

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Quick and simple detection technique to assess the binding of antimicrotubule agents to the colchicine-binding site.
Sébastien Fortin, Jacques Lacroix, Marie-France Côté, Emmanuel Moreau, Eric Petitclerc

Biol Proced Online· April 2010

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Tumor cells expressing tissue factor influence the migration of smooth muscle cells in a catalytic activity-dependent way.
Catherine Brousseau, Guillaume Morissette, Jean-Philippe Fortin, François Marceau, Eric Petitclerc

Can J Physiol Pharmacol· September 2009

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On the ability of imatinib mesylate to inhibit smooth muscle cell proliferation without delaying endothelialization: an in vitro study.
Karine Vallières, Eric Petitclerc, Gaétan Laroche

Vascul Pharmacol· July 2009

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Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin.
Sébastien Fortin, Lianhu Wei, Emmanuel Moreau, Philippe Labrie, Eric Petitclerc

Bioorg Med Chem· May 2009

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Receptor tyrosine kinases as mediators of injury-induced bradykinin B1 receptor expression in rabbit aortic smooth muscle.
Gérémy Abdull Koumbadinga, Eric Petitclerc, Johanne Bouthillier, Albert Adam, François Marceau

Eur J Pharmacol· March 2009

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Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression.
Jessica S Fortin, Marie-France Côté, Jacques Lacroix, Eric Petitclerc, René C-Gaudreault

Bioorg Med Chem· August 2008

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Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents.
Jessica S Fortin, Marie-France Côté, Jacques Lacroix, Michel Desjardins, Eric Petitclerc

Bioorg Med Chem· August 2008

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Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation.
Jessica S Fortin, Marie-France Côté, Jacques Lacroix, Alexandre Patenaude, Eric Petitclerc

Bioorg Med Chem Lett· June 2008

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Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site.
Jessica S Fortin, Jacques Lacroix, Michel Desjardins, Alexandre Patenaude, Eric Petitclerc

Bioorg Med Chem· July 2007

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Covalent grafting of fibronectin onto plasma-treated PTFE: influence of the conjugation strategy on fibronectin biological activity.
Karine Vallières, Eric Petitclerc, Gaétan Laroche

Macromol Biosci· May 2007

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New soft alkylating agents with enhanced cytotoxicity against cancer cells resistant to chemotherapeutics and hypoxia.
Alexandre Patenaude, Réna G Deschesnes, Jean L C Rousseau, Eric Petitclerc, Jacques Lacroix

Cancer Res· March 2007

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Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells.
Réna G Deschesnes, Alexandre Patenaude, Jean L C Rousseau, Jessica S Fortin, Christine Ricard, Eric Petitclerc

J Pharmacol Exp Ther· February 2007

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Optimized N-phenyl-N'-(2-chloroethyl)ureas as potential antineoplastic agents: synthesis and growth inhibition activity.
Emmanuel Moreau, Sébastien Fortin, Michel Desjardins, Jean L C Rousseau, Eric Petitclerc

Bioorg Med Chem· December 2005

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MMP-2 expression in uveal melanoma: differential activation status dictated by the cellular environment.
Mélanie Bérubé, Alexandre Deschambeault, Maryse Boucher, Lucie Germain, Eric Petitclerc

Mol Vis· December 2005

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Engineering surfaces for bioconjugation: developing strategies and quantifying the extent of the reactions.
Virginie Gauvreau, Pascale Chevallier, Karine Vallières, Eric Petitclerc, René C Gaudreault

Bioconjug Chem· February 2005

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Role of the extracellular matrix proteins in the resistance of SP6.5 uveal melanoma cells toward cisplatin.
Mélanie Bérubé, Mariève Talbot, Charles Collin, Carine Paquet-Bouchard, Lucie Germain, Eric Petitclerc

Int J Oncol· February 2005

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Loss of function of vascular smooth muscle cells by nitric oxide-dependent and -independent interactions with tumorigenic cells.
Guillaume Morissette, Eric Petitclerc, François Marceau

Int J Cancer· December 2004

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