Publications by authors named "Eric Wadman"

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Clinical efficacy and IL-17 targeting mechanism of Indigo naturalis as a topical agent in moderate psoriasis.
Hui-Man Cheng, Yang-Chang Wu, Qingmin Wang, Michael Song, Jackson Wu, Eric Wadman

BMC Complement Altern Med· September 2017

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Immune response to pneumococcus and tetanus toxoid in patients with moderate-to-severe psoriasis following long-term ustekinumab use.
Carrie Brodmerkel, Eric Wadman, Richard G Langley, Kim A A Papp, Marc Bourcier

J Drugs Dermatol· October 2013

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From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis.
Joseph B Santella, Daniel S Gardner, Wenqing Yao, Chongsheng Shi, Prabhakar Reddy, Eric A Wadman

Bioorg Med Chem Lett· January 2008

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From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists.
Daniel S Gardner, Joseph B Santella, Andrew J Tebben, Douglas G Batt, Soo S Ko, Eric A Wadman

Bioorg Med Chem Lett· January 2008

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CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicity.
James R Pruitt, Douglas G Batt, Dean A Wacker, Lori L Bostrom, Shon K Booker, Eric A Wadman

Bioorg Med Chem Lett· June 2007

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2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivity.
Paul S Watson, Bin Jiang, Kim Harrison, Nao Asakawa, Patricia K Welch, Eric A Wadman

Bioorg Med Chem Lett· November 2006

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Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation.
Anuk M Das, Krishna G Vaddi, Kimberly A Solomon, Candice Krauthauser, Xiaosui Jiang, Eric Wadman

J Pharmacol Exp Ther· July 2006

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Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.
George V De Lucca, Ui Tae Kim, Brian J Vargo, John V Duncia, Joseph B Santella, Eric A Wadman

J Med Chem· March 2005

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N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists.
Douglas G Batt, Gregory C Houghton, John Roderick, Joseph B Santella, Dean A Wacker, Eric A Wadman

Bioorg Med Chem Lett· February 2005

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Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists.
Jeffrey G Varnes, Daniel S Gardner, Joseph B Santella, John V Duncia, Melissa Estrella, Eric Wadman

Bioorg Med Chem Lett· April 2004

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CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships.
Dean A Wacker, Joseph B Santella, Daniel S Gardner, Jeffrey G Varnes, Melissa Estrella, Eric A Wadman

Bioorg Med Chem Lett· July 2002

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