Publications by authors named "Eric Weh"

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A Novel, Long-Acting, Small Molecule PKM2 Activator and Its Potential Broad Application Against Photoreceptor Degeneration.
Warren W Pan, Katherine M Weh, Sraboni Chaudhury, Roshini Fernando, Heather Hager, Eric Weh

Transl Vis Sci Technol· July 2025

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Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival.
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla

Elife· May 2025

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Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival.
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla

bioRxiv· February 2025

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Photoreceptor Degeneration: More Than a Bystander in Age-Related Macular Degeneration.
Thomas J Wubben, Eric Weh, Cagri G Besirli

Adv Exp Med Biol· February 2025

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Rod photoreceptor-specific deletion of cytosolic aspartate aminotransferase, GOT1, causes retinal degeneration.
Shubha Subramanya, Moloy T Goswami, Nicholas Miller, Eric Weh, Sraboni Chaudhury, Katherine M Weh

Front Ophthalmol (Lausanne)· December 2023

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Flow cytometric method for the detection and quantification of retinal cell death and oxidative stress.
Shubha Subramanya, Roshini Fernando, Moloy Goswami, Cagri G Besirli, Eric Weh

Exp Eye Res· August 2023

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Metabolic Alterations Caused by Simultaneous Loss of HK2 and PKM2 Leads to Photoreceptor Dysfunction and Degeneration.
Eric Weh, Moloy Goswami, Sraboni Chaudhury, Roshini Fernando, Nick Miller

Cells· August 2023

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Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis.
Thomas J Wubben, Sraboni Chaudhury, Brennan T Watch, Jeanne A Stuckey, Eric Weh

Pharmaceuticals (Basel)· May 2023

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Synthetic high-density lipoprotein nanoparticles delivering rapamycin for the treatment of age-related macular degeneration.
Ling Mei, Minzhi Yu, Yayuan Liu, Eric Weh, Mercy Pawar

Nanomedicine· August 2022

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Dark-reared rd10 mice experience rapid photoreceptor degeneration with short exposure to room-light during in vivo retinal imaging.
Eric Weh, Kennedi Scott, Thomas J Wubben, Cagri G Besirli

Exp Eye Res· February 2022

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Hexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress.
Eric Weh, Zuzanna Lutrzykowska, Andrew Smith, Heather Hager, Mercy Pawar

Cell Death Dis· June 2020

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Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, circumvents photoreceptor apoptosis.
Thomas J Wubben, Mercy Pawar, Eric Weh, Andrew Smith, Peter Sajjakulnukit

Sci Rep· February 2020

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Analysis of in pediatric and adult glaucoma and other ocular phenotypes.
Linda M Reis, Rebecca C Tyler, Eric Weh, Kathryn E Hendee, Ariana Kariminejad

Mol Vis· January 2018

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Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome.
Eric Weh, Hideyuki Takeuchi, Sanaa Muheisen, Robert S Haltiwanger, Elena V Semina

PLoS One· October 2017

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Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma.
Meredith E Protas, Eric Weh, Tim Footz, Jay Kasberger, Scott C Baraban

Hum Mol Genet· September 2017

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8q21.11 microdeletion in two patients with syndromic peters anomaly.
Hannah Happ, Kala F Schilter, Eric Weh, Linda M Reis, Elena V Semina

Am J Med Genet A· September 2016

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Case report of homozygous deletion involving the first coding exons of GCNT2 isoforms A and B and part of the upstream region of TFAP2A in congenital cataract.
Hannah Happ, Eric Weh, Deborah Costakos, Linda M Reis, Elena V Semina

BMC Med Genet· September 2016

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Whole exome sequence analysis of Peters anomaly.
Eric Weh, Linda M Reis, Hannah C Happ, Alex V Levin, Patricia G Wheeler

Hum Genet· December 2014

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Race- and sex-related differences in retinal thickness and foveal pit morphology.
Melissa Wagner-Schuman, Adam M Dubis, Rick N Nordgren, Yuming Lei, Daniel Odell, Eric Weh

Invest Ophthalmol Vis Sci· January 2011

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