Publications by authors named "Eric Witze"

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A selective S-acyltransferase inhibitor suppresses tumor growth.
Jia-Ying Lee, Sebastian Dilones, Timothe Maujean, Mohammad Asad, Altaf Mohd, Eric S Witze

bioRxiv· July 2024

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Chemical probe mediated visualization of protein S-palmitoylation in patient tissue samples.
Nancy Schek, Jia-Ying Lee, George M Burslem, Eric Witze

Front Physiol· February 2023

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Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis.
Yasmin A Kadry, Jia-Ying Lee, Eric S Witze

Open Biol· October 2021

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Acute Regulation of Habituation Learning via Posttranslational Palmitoylation.
Jessica C Nelson, Eric Witze, Zhongming Ma, Francesca Ciocco, Abigaile Frerotte

Curr Biol· July 2020

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Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis.
Akriti Kharbanda, David M Walter, Andrea A Gudiel, Nancy Schek, David M Feldser, Eric S Witze

Sci Signal· March 2020

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Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior.
Rochelle Shirin Sadeghi, Katarzyna Kulej, Rahul Singh Kathayat, Benjamin A Garcia, Bryan C Dickinson, Eric S Witze

Elife· April 2018

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Wnt-Dependent Control of Cell Polarity in Cultured Cells.
Kristin B Runkle, Eric S Witze

Methods Mol Biol· January 2018

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The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division.
Ewa Stypulkowski, Irfan A Asangani, Eric S Witze

Sci Signal· January 2018

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Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras.
Akriti Kharbanda, Kristin Runkle, Wei Wang, Eric S Witze

Biochem Biophys Res Commun· November 2017

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A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.
Vito W Rebecca, Michael C Nicastri, Noel McLaughlin, Colin Fennelly, Quentin McAfee, Eric Witze

Cancer Discov· November 2017

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Menin localization in cell membrane compartment.
Xin He, Lei Wang, Jizhou Yan, Chaoxing Yuan, Eric S Witze

Cancer Biol Ther· October 2016

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Spontaneous Cell Competition in Immortalized Mammalian Cell Lines.
Alfredo I Penzo-Méndez, Yi-Ju Chen, Jinyang Li, Eric S Witze, Ben Z Stanger

PLoS One· May 2016

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Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling.
Kristin B Runkle, Akriti Kharbanda, Ewa Stypulkowski, Xing-Jun Cao, Wei Wang, Eric S Witze

Mol Cell· May 2016

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Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior.
Wei Wang, Kristin B Runkle, Samantha M Terkowski, Rachel I Ekaireb, Eric S Witze

J Biol Chem· June 2015

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A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype.
Michael P Schwartz, Robert E Rogers, Samir P Singh, Justin Y Lee, Samuel G Loveland, Eric S Witze

PLoS One· September 2014

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DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation.
Tatiana Londoño Gentile, Chao Lu, Peter M Lodato, Sarah Tse, Scott H Olejniczak, Eric S Witze

Mol Cell Biol· October 2013

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Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge.
Eric S Witze, Mary Katherine Connacher, Stephane Houel, Michael P Schwartz, Mary K Morphew

Dev Cell· September 2013

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Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response.
Carly M Sayers, Ioanna Papandreou, David M Guttmann, Nancy L Maas, J Alan Diehl, Eric S Witze

Mol Pharmacol· March 2013

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PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation.
Ekaterina Bobrovnikova-Marjon, Dariusz Pytel, Matthew J Riese, Laura Pontano Vaites, Nickpreet Singh, Eric S Witze

Mol Cell Biol· June 2012

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A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme.
Yukihito Kabuyama, Elizabeth S Litman, Paul D Templeton, Sandra I Metzner, Eric S Witze

Mol Cell Proteomics· October 2009

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Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma.
William M Old, John B Shabb, Stephane Houel, Hong Wang, Kasey L Couts, Eric S Witze

Mol Cell· April 2009

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C. elegans pur alpha, an activator of end-1, synergizes with the Wnt pathway to specify endoderm.
Eric S Witze, Erin D Field, Donald F Hunt, Joel H Rothman

Dev Biol· March 2009

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Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors.
Eric S Witze, Elizabeth S Litman, Gretchen M Argast, Randall T Moon, Natalie G Ahn

Science· April 2008

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Mapping protein post-translational modifications with mass spectrometry.
Eric S Witze, William M Old, Katheryn A Resing, Natalie G Ahn

Nat Methods· October 2007

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Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans.
Tim A Bloss, Eric S Witze, Joel H Rothman

Nature· August 2003

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