Publications by authors named "Erin Coffee"

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Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer.
Jatin Roper, Mark J Sinnamon, Erin M Coffee, Peter Belmont, Lily Keung

Cancer Lett· June 2014

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Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease.
Peter J Belmont, Eva Budinska, Ping Jiang, Mark J Sinnamon, Erin Coffee

Dis Model Mech· June 2014

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mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Anthony C Faber, Erin M Coffee, Carlotta Costa, Anahita Dastur, Hiromichi Ebi

Cancer Discov· January 2014

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Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.
Eric S Martin, Peter J Belmont, Mark J Sinnamon, Larissa Georgeon Richard, Jing Yuan, Erin M Coffee

Clin Cancer Res· June 2013

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Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.
Erin M Coffee, Anthony C Faber, Jatin Roper, Mark J Sinnamon, Gautam Goel

Clin Cancer Res· May 2013

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Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models.
Ryan B Corcoran, Katherine A Cheng, Aaron N Hata, Anthony C Faber, Hiromichi Ebi, Erin M Coffee

Cancer Cell· January 2013

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EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Ryan B Corcoran, Hiromichi Ebi, Alexa B Turke, Erin M Coffee, Michiya Nishino

Cancer Discov· March 2012

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The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.
Jatin Roper, Michael P Richardson, Wei Vivian Wang, Larissa Georgeon Richard, Wei Chen, Erin M Coffee

PLoS One· February 2012

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Mutations in the promoter region of the aldolase B gene that cause hereditary fructose intolerance.
Erin M Coffee, Dean R Tolan

J Inherit Metab Dis· December 2010

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Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population.
Erin M Coffee, Laura Yerkes, Elizabeth P Ewen, Tiffany Zee, Dean R Tolan

J Inherit Metab Dis· February 2010

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