Publications by authors named "Erwan Ayral"

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Synthesis of new 8(S)-HETE analogs and their biological evaluation as activators of the PPAR nuclear receptors.
Mélanie Liutkus, Frédéric Caijo, Anne-Lise Girard, Erwan Ayral, Valérie Audinot

J Enzyme Inhib Med Chem· October 2010

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Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
Jean Sevalle, Erwan Ayral, Jean-François Hernandez, Jean Martinez, Frédéric Checler

J Neurochem· July 2009

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Design, synthesis, and biological evaluation of 1,5-benzothiazepine-4-one derivatives targeting factor VIIa/tissue factor.
Erwan Ayral, Philippe Gloanec, Gilbert Bergé, Guillaume de Nanteuil, Philippe Mennecier

Bioorg Med Chem Lett· March 2009

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JLK inhibitors: isocoumarin compounds as putative probes to selectively target the gamma-secretase pathway.
Frédéric Checler, Cristine Alves da Costa, Erwan Ayral, David Andrau, Cécile Dumanchin

Curr Alzheimer Res· July 2005

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Presenilin-directed inhibitors of gamma-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells.
Cristine Alves da Costa, Erwan Ayral, Jean-François Hernandez, Peter St George-Hyslop, Frédéric Checler

J Neurochem· August 2004

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BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors.
David Andrau, Cecile Dumanchin-Njock, Erwan Ayral, Jean Vizzavona, Mike Farzan

J Biol Chem· July 2003

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