Publications by authors named "Esther Guzman"

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The Marine Natural Compound Aplysinamisine I Selectively Induces Apoptosis and Exhibits Synergy with Taxol™ in Triple-Negative Breast Cancer Spheroids.
Esther A Guzmán, Tara A Peterson, Dedra K Harmody, Amy E Wright

Mar Drugs· September 2025

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A novel treatment to enhance survival for end stage triple negative breast cancer using repurposed veterinary anthelmintics combined with gut‑supporting/immune enhancing molecules.
Vijaya Iragavarapu-Charyulu, Rojesh Shakya, Philip Robinson, Esther Guzmán, Anastasia Tyulmenkova

Oncol Rep· February 2024

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The Marine Natural Compound Dragmacidin D Selectively Induces Apoptosis in Triple-Negative Breast Cancer Spheroids.
Esther A Guzmán, Tara A Peterson, Amy E Wright

Mar Drugs· December 2023

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An Assessment of Potential Threats to Human Health from Algae Blooms in the Indian River Lagoon (USA) 2018-2021: Unique Patterns of Cytotoxicity Associated with Toxins.
Esther A Guzmán, Tara A Peterson, Priscilla L Winder, Kirstie T Francis, Malcolm McFarland

Toxins (Basel)· November 2023

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Brominated and Sulfur-Containing Angucyclines Derived from a Single Pathway: Identification of Nocardiopsistins D-F.
Dongbo Xu, Jackie Metz, Dedra Harmody, Tara Peterson, Priscilla Winder

Org Lett· November 2022

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High-Throughput Screening of a Marine Compound Library Identifies Anti- Activity of Leiodolide A.
Rachel M Bone Relat, Priscilla L Winder, Gregory D Bowden, Esther A Guzmán, Tara A Peterson

Mar Drugs· March 2022

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The Marine Natural Product Furospinulosin 1 Induces Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cell Spheroids, But Not in Cells Grown Traditionally with Longer Treatment.
Esther A Guzmán, Tara P Pitts, Priscilla L Winder, Amy E Wright

Mar Drugs· April 2021

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Corrigendum to Dynamics of microcystins and saxitoxin in the Indian River Lagoon, Florida Harmful Algae 103C (2021) 102012.
Abdiel E Laureano-Rosario, Malcolm McFarland, David J Bradshaw, Jackie Metz, Rachel A Brewton

Harmful Algae· April 2021

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Dynamics of microcystins and saxitoxin in the Indian River Lagoon, Florida.
Abdiel E Laureano-Rosario, Malcolm McFarland, David J Bradshaw, Jackie Metz, Rachel A Brewton

Harmful Algae· March 2021

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Solvatochromic and pH-Sensitive Fluorescent Membrane Probes for Imaging of Live Cells.
Deborah Thomas, Vicente Rubio, Vijaya Iragavarapu, Esther Guzman, Oliver B Pelletier

ACS Chem Neurosci· February 2021

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Discovery of Survivin Inhibitors Part 1: Screening the Harbor Branch Pure Compound Library.
Esther A Guzmán, Tara P Pitts, Kirstie R Tandberg, Priscilla L Winder, Amy E Wright

Mar Drugs· January 2021

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The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines.
Esther Amalia Guzmán, Tara Peterson Pitts, Maria Cristina Diaz, Amy Elizabeth Wright

Invest New Drugs· April 2019

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Regulated Cell Death Signaling Pathways and Marine Natural Products That Target Them.
Esther A Guzmán

Mar Drugs· January 2019

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Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium.
Amy E Wright, Jill C Roberts, Esther A Guzmán, Tara P Pitts, Shirley A Pomponi

J Nat Prod· March 2017

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Inhibition of IL-8 secretion on BxPC-3 and MIA PaCa-2 cells and induction of cytotoxicity in pancreatic cancer cells with marine natural products.
Esther A Guzmán, Dedra Harmody, Tara P Pitts, Brunilda Vera-Diaz, Priscilla L Winder

Anticancer Drugs· February 2017

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Dragmacidin G, a Bioactive Bis-Indole Alkaloid from a Deep-Water Sponge of the Genus Spongosorites.
Amy E Wright, K Brian Killday, Debopam Chakrabarti, Esther A Guzmán, Dedra Harmody

Mar Drugs· January 2017

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Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Esther A Guzmán, Qunli Xu, Tara P Pitts, Kaoru Ogawa Mitsuhashi, Cheryl Baker

Int J Cancer· November 2016

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Toward the identification, characterization and experimental culture of Lacazia loboi from Atlantic bottlenose dolphin (Tursiops truncatus).
Adam M Schaefer, John S Reif, Esther A Guzmán, Gregory D Bossart, Patrick Ottuso

Med Mycol· August 2016

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The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells.
Esther A Guzmán, Kelly Maers, Jill Roberts, Hilaire V Kemami-Wangun, Dedra Harmody

Invest New Drugs· February 2015

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The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells.
Georgios Kallifatidis, Dominic Hoepfner, Tiphaine Jaeg, Esther A Guzmán, Amy E Wright

Mar Drugs· September 2013

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Spongiatriol inhibits nuclear factor kappa B activation and induces apoptosis in pancreatic cancer cells.
Esther Guzmán, Michael Maher, Alexis Temkin, Tara Pitts, Amy Wright

Mar Drugs· April 2013

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Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima.
Priscilla L Winder, Heather L Baker, Patricia Linley, Esther A Guzmán, Shirley A Pomponi

Bioorg Med Chem· November 2011

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A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis.
Esther A Guzmán, Jacob D Johnson, Patricia A Linley, Sarath E Gunasekera, Amy E Wright

Invest New Drugs· October 2011

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Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
Ian Paterson, Stephen M Dalby, Jill C Roberts, Guy J Naylor, Esther A Guzmán

Angew Chem Int Ed Engl· March 2011

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Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
Ian Paterson, Guy J Naylor, Nicola M Gardner, Esther Guzmán, Amy E Wright

Chem Asian J· February 2011

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