Publications by authors named "Patricia Linley"

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Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Esther A Guzmán, Qunli Xu, Tara P Pitts, Kaoru Ogawa Mitsuhashi, Cheryl Baker, Patricia A Linley

Int J Cancer· November 2016

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Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima.
Priscilla L Winder, Heather L Baker, Patricia Linley, Esther A Guzmán, Shirley A Pomponi

Bioorg Med Chem· November 2011

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A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis.
Esther A Guzmán, Jacob D Johnson, Patricia A Linley, Sarath E Gunasekera, Amy E Wright

Invest New Drugs· October 2011

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Isolation, synthesis, and biological activity of aphrocallistin, an adenine-substituted bromotyramine metabolite from the Hexactinellida sponge Aphrocallistes beatrix.
Amy E Wright, Gregory P Roth, Jennifer K Hoffman, Daniela B Divlianska, Diana Pechter, Patricia Linley

J Nat Prod· June 2009

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Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae.
Amy E Wright, Julianne Cook Botelho, Esther Guzmán, Dedra Harmody, Patricia Linley

J Nat Prod· March 2007

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Synthetic analogues of the microtubule-stabilizing agent (+)-discodermolide: preparation and biological activity.
Sarath P Gunasekera, Stuart J Mickel, Robert Daeffler, Daniel Niederer, Amy E Wright, Patricia Linley

J Nat Prod· May 2004

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