Publications by authors named "Etienne Lessard"

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Engineered multifunctional transforming growth factor-β type II receptor ectodomain fusions for oncology applications.
Anne E G Lenferink, John C Zwaagstra, Jason Baardsnes, Laurence Delafosse, Marie Parat, Etienne Lessard

Front Oncol· November 2025

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In vivo brain delivery of BBB-enabled iduronate 2-sulfatase in rats.
Will J Costain, Arsalan S Haqqani, Greg Hussack, Henk van Faassen, Etienne Lessard

Fluids Barriers CNS· January 2025

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A Novel Antigen Design Strategy to Isolate Single-Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models.
Marzia Martina, Umberto Banderali, Alvaro Yogi, Mehdi Arbabi Ghahroudi, Hong Liu, Etienne Lessard

Adv Sci (Weinh)· October 2024

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Pharmacokinetics and Pharmacodynamic Effect of a Blood-Brain Barrier-Crossing Fusion Protein Therapeutic for Alzheimer's Disease in Rat and Dog.
Etienne Lessard, Kerry Rennie, Arsalan Haqqani, Binbing Ling, James Whitfield

Pharm Res· July 2022

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Preclinical longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.
Min Su Kang, Monica Shin, Julie Ottoy, Arturo Aliaga Aliaga, Sulantha Mathotaarachchi, Etienne Lessard

J Cereb Blood Flow Metab· May 2022

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7-Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins.
Andreas Geissner, Lars Baumann, Thomas J Morley, Andrew K O Wong, Lyann Sim, Etienne Lessard

ACS Cent Sci· February 2021

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Enhanced anti-metastatic bioactivity of an IGF-TRAP re-engineered to improve physicochemical properties.
George Vaniotis, Serge Moffett, Traian Sulea, Ni Wang, S Mehdy Elahi, Etienne Lessard

Sci Rep· November 2018

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Feasibility of real-time motion management with helical tomotherapy.
Eric Schnarr, Matt Beneke, Dylan Casey, Edward Chao, Jonathan Chappelow, Etienne Lessard

Med Phys· April 2018

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Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26.
George Thom, Matthew Burrell, Arsalan S Haqqani, Alvaro Yogi, Etienne Lessard

Mol Pharm· April 2018

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Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients.
Christopher M McGuinness, Alexander R Gottschalk, Etienne Lessard, Jean L Nakamura, Dilini Pinnaduwage

J Appl Clin Med Phys· September 2015

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Evaluation of an innovative population pharmacokinetic-based design for behavioral pharmacodynamic endpoints.
Anders Viberg, Giovanni Martino, Etienne Lessard, Jennifer M A Laird

AAPS J· December 2012

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N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.
Zhongyong Wei, Hua Yang, Ziping Liu, Maxime Tremblay, Shawn Johnstone, Etienne Lessard

Bioorg Med Chem Lett· June 2012

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γ-Carbolines: a novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration.
Yun-Xing Cheng, Mehrnaz Pourashraf, Xuehong Luo, Sanjay Srivastava, Christopher Walpole, Etienne Lessard

Bioorg Med Chem Lett· February 2012

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Blocking spinal CCR2 with AZ889 reversed hyperalgesia in a model of neuropathic pain.
Alexandre Serrano, Michel Paré, Fraser McIntosh, Steven J R Elmes, Giovanni Martino, Etienne Lessard

Mol Pain· December 2010

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A peripherally restricted cannabinoid receptor agonist produces robust anti-nociceptive effects in rodent models of inflammatory and neuropathic pain.
Xiao Hong Yu, Chang Qing Cao, Giovanni Martino, Carole Puma, Anne Morinville, Étienne Lessard

Pain· November 2010

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Inverse planning simulated annealing for magnetic resonance imaging-based intracavitary high-dose-rate brachytherapy for cervical cancer.
Charlotte Dai Kubicky, Benjamin M Yeh, Etienne Lessard, Bonnie N Joe, Joycelyn L Speight

Brachytherapy· November 2008

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Class solution in inverse planned HDR prostate brachytherapy for dose escalation of DIL defined by combined MRI/MRSI.
Yongbok Kim, I-Chow J Hsu, Etienne Lessard, John Kurhanewicz, Susan Moyher Noworolski

Radiother Oncol· July 2008

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Relationship between isotope half-life and prostatic edema for optimal prostate dose coverage in permanent seed implants.
Maxime Villeneuve, Ghyslain Leclerc, Etienne Lessard, Jean Pouliot, Luc Beaulieu

Med Phys· May 2008

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Optimization of HDR brachytherapy dose distributions using linear programming with penalty costs.
Ron Alterovitz, Etienne Lessard, Jean Pouliot, I-Chow Joe Hsu, James F O'Brien

Med Phys· November 2006

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Class solution for inversely planned permanent prostate implants to mimic an experienced dosimetrist.
Etienne Lessard, Stefan L S Kwa, Barby Pickett, Mach Roach, Jean Pouliot

Med Phys· August 2006

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Optimization of dose distribution for HDR brachytherapy of the prostate using Attraction-Repulsion Model.
Iori Sumida, Hiroya Shiomi, Yasuo Yoshioka, Takehiro Inoue, Etienne Lessard

Int J Radiat Oncol Biol Phys· February 2006

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3D inverse treatment planning for the tandem and ovoid applicator in cervical cancer.
Kelly D Dewitt, I Chow Joe Hsu, Joycelyn Speight, Vivian K Weinberg, Etienne Lessard

Int J Radiat Oncol Biol Phys· November 2005

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Anatomy-based inverse planning dose optimization in HDR prostate implant: a toxicity study.
Alireza Mahmoudieh, Christine Tremblay, Luc Beaulieu, Bernard Lachance, François Harel, Etienne Lessard

Radiother Oncol· June 2005

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Comparison of inverse planning simulated annealing and geometrical optimization for prostate high-dose-rate brachytherapy.
I-Chow J Hsu, Etienne Lessard, Vivian Weinberg, Jean Pouliot

Brachytherapy· May 2005

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Inverse treatment planning based on MRI for HDR prostate brachytherapy.
Deborah Citrin, Holly Ning, Peter Guion, Guang Li, Robert C Susil, Etienne Lessard

Int J Radiat Oncol Biol Phys· March 2005

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