Publications by authors named "Ewan D Fowler"

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Calmodulin D133H Disrupts Ca1.2 and K7.1 Regulation to Prolong Cardiac Action Potentials in Long QT Syndrome.
Nitika Gupta, Liam F McCormick, Ella M B Richards, Kirsty Wadmore, Rachael Morris, Ewan D Fowler

Cells· November 2025

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Disruption of ventricular activation by subthreshold delayed afterdepolarizations in RyR2-R420Q catecholaminergic polymorphic ventricular tachycardia.
Ewan D Fowler, Salimata L Diakite, Ana M Gomez, Michael A Colman

J Mol Cell Cardiol Plus· September 2025

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Compromised repolarization reserve in a murine model of catecholaminergic polymorphic ventricular tachycardia caused by RyR2-R420Q mutation.
Spyros Zissimopoulos, Pavel Kirilenko, Aitana Braza-Boïls, Esther Zorio, Yueyi Wang, Ewan D Fowler

J Mol Cell Cardiol· September 2025

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Editorial: Stretch and the heart: mechanoelectrical coupling and arrhythmias.
Ewan Douglas Fowler, Jan E Azarov, Fabien Brette

Front Physiol· August 2023

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Improved Ca release synchrony following selective modification of I and phase 1 repolarization in normal and failing ventricular myocytes.
Ewan D Fowler, Nan Wang, Melanie J Hezzell, Guillaume Chanoit, Jules C Hancox

J Mol Cell Cardiol· November 2022

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Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease.
Ewan Douglas Fowler, Spyros Zissimopoulos

Biomolecules· July 2022

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Inducing I and phase 1 repolarization of the cardiac action potential with a Kv4.3/KChIP2.1 bicistronic transgene.
Nan Wang, Eef Dries, Ewan D Fowler, Stephen C Harmer, Jules C Hancox

J Mol Cell Cardiol· March 2022

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Arrhythmogenic late Ca sparks in failing heart cells and their control by action potential configuration.
Ewan D Fowler, Nan Wang, Melanie Hezzell, Guillaume Chanoit, Jules C Hancox

Proc Natl Acad Sci U S A· February 2020

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Energy Metabolism in the Failing Right Ventricle: Limitations of Oxygen Delivery and the Creatine Kinase System.
Ewan D Fowler, David Hauton, John Boyle, Stuart Egginton, Derek S Steele

Int J Mol Sci· April 2019

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Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca handling dysfunction in rats with pulmonary artery hypertension.
Ewan D Fowler, Mark J Drinkhill, Ruth Norman, Eleftheria Pervolaraki, Rachel Stones

J Mol Cell Cardiol· July 2018

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Diastolic dysfunction in pulmonary artery hypertension: Creatine kinase and the potential therapeutic benefit of beta-blockers.
Ewan D Fowler, Mark J Drinkhill, Rachel Stones, Ed White

Clin Exp Pharmacol Physiol· April 2018

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Late Ca Sparks and Ripples During the Systolic Ca Transient in Heart Muscle Cells.
Ewan D Fowler, Cherrie H T Kong, Jules C Hancox, Mark B Cannell

Circ Res· February 2018

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Synergistic role of ADP and Ca(2+) in diastolic myocardial stiffness.
Vasco Sequeira, Aref Najafi, Mark McConnell, Ewan D Fowler, Ilse A E Bollen

J Physiol· September 2015

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Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension.
Ewan D Fowler, David Benoist, Mark J Drinkhill, Rachel Stones, Michiel Helmes

J Mol Cell Cardiol· September 2015

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Voluntary exercise delays heart failure onset in rats with pulmonary artery hypertension.
Antonio J Natali, Ewan D Fowler, Sarah C Calaghan, Ed White

Am J Physiol Heart Circ Physiol· August 2015

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Systems approach to the study of stretch and arrhythmias in right ventricular failure induced in rats by monocrotaline.
David Benoist, Rachel Stones, Alan P Benson, Ewan D Fowler, Mark J Drinkhill

Prog Biophys Mol Biol· August 2014

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