Publications by authors named "Fangbin Han"

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BET degrader exhibits lower antiproliferative activity than its inhibitor via EGR1 recruiting septins to promote E2F1-3 transcription in triple-negative breast cancer.
Nan Liu, Shuai Wang, Munan Li, Nan Zhao, Deyu Wang, Rui Zhang, Siwei Zhang, Fangbin Han

Pharmacol Res· October 2024

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Do the asymmetric effects of eco-digitalization amidst energy transition make or mar the strides toward environmental sustainability in the USA?
Fangbin Han, Ridwan Lanre Ibrahim, Jun Tang, Usama Al-Mulali

Environ Sci Pollut Res Int· December 2023

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BRD4-PRC2 represses transcription of T-helper 2-specific negative regulators during T-cell differentiation.
Li Zhao, Yiqi Wang, Anbalagan Jaganathan, Yifei Sun, Ning Ma, Xinye Han, Fangbin Han

EMBO J· March 2023

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Small Molecules with Big Promises for Curing Demyelinating Diseases.
Fangbin Han, Ming-Ming Zhou

Cell Chem Biol· April 2019

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Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Chunyan Ren, Guangtao Zhang, Fangbin Han, Shibo Fu, Yingdi Cao, Fan Zhang, Qiang Zhang, Weijia Zhang

Proc Natl Acad Sci U S A· July 2018

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Discovery of new thienopyrimidine derivatives as potent and orally efficacious phosphoinositide 3-kinase inhibitors.
Songwen Lin, Chunyang Wang, Ming Ji, Deyu Wu, Yuanhao Lv, Fangbin Han, Kehui Zhang

Bioorg Med Chem· February 2018

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Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors.
Yonghui Wang, Wei Cai, Yaobang Cheng, Ting Yang, Qian Liu, Guifeng Zhang, Fangbin Han

ACS Med Chem Lett· July 2015

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Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors.
Fangbin Han, Songwen Lin, Peng Liu, Xiujie Liu, Jing Tao

ACS Med Chem Lett· April 2015

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Synthesis and structure-activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives.
Fangbin Han, Songwen Lin, Peng Liu, Jing Tao, Chongqin Yi

Bioorg Med Chem Lett· September 2014

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Identification of novel 7-amino-5-methyl-1,6-naphthyridin-2(1H)-one derivatives as potent PI3K/mTOR dual inhibitors.
Songwen Lin, Fangbin Han, Peng Liu, Jing Tao, Xuechao Zhong

Bioorg Med Chem Lett· February 2014

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Discovery of thiadiazole amides as potent, S1P₃-sparing agonists of sphingosine-1-phosphate 1 (S1P₁) receptor.
Heng Xu, Haibo Zhang, Linbo Luan, Yan Xu, Chengyong Li, Fangbin Han, Wei Zhang

Bioorg Med Chem Lett· April 2012

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Simultaneous determination of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride and its major metabolite in rats by HPLC.
Xiaomei Jiang, Yihao Bai, Xiaomei Ling, Fangbin Han, Runtao Li

J Chromatogr Sci· February 2010

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Studies on the metabolism of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride in rats by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Xiaomei Jiang, Xiaomei Ling, Fangbin Han, Runtao Li, Jingrong Cui

J Pharm Biomed Anal· September 2007

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Studies on the metabolism of 4-methylpiperazine-1-carbodithioc acid 3-cyano-3,3- diphenylpropyl ester hydrochloride in rat bile by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Xiaomei Jiang, Detao Kong, Fangbin Han, Xiaomei Ling, Xiaoyan Liu

Rapid Commun Mass Spectrom· August 2007

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Analysis of 4-methyl-piperazine-1-carbodithioic acid 3-cyano-3,3-diphenyl-propyl ester hydrochloride and its major metabolites in rat plasma and tissues by LC-MS/MS.
Xiaomei Jiang, Xiaomei Ling, Fangbin Han, Runtao Li, Jingrong Cui

J Sep Sci· August 2007

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