Publications by authors named "Felix Bachmann"

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Dual TTK/PLK1 inhibition has potent anticancer activity in TNBC as monotherapy and in combination.
Elisa Zanini, Nicole Forster-Gross, Felix Bachmann, Adrian Brüngger, Paul McSheehy

Front Oncol· August 2024

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The microtubule-targeted agent lisavanbulin (BAL101553) shows anti-tumor activity in lymphoma models.
Filippo Spriano, Luca Aresu, Luciano Cascione, Giorgia Risi, Alberto J Arribas, Felix Bachmann

Am J Cancer Res· May 2023

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The fibroblast growth factor receptor inhibitor, derazantinib, has strong efficacy in human gastric tumor models and synergizes with paclitaxel in vivo.
Paul M J McSheehy, Nicole Forster-Gross, Mahmoud El Shemerly, Felix Bachmann, Mila Roceri

Anticancer Drugs· April 2023

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Enzymatic post-treatment of ozonation: laccase-mediated removal of the by-products of acetaminophen ozonation.
Dorothee Schmiemann, Lisa Hohenschon, Indra Bartels, Andrea Hermsen, Felix Bachmann

Environ Sci Pollut Res Int· April 2023

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Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.
Danielle M Burgenske, Surabhi Talele, Jenny L Pokorny, Ann C Mladek, Katrina K Bakken, Felix Bachmann

Neuro Oncol· March 2022

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Derazantinib: an investigational drug for the treatment of cholangiocarcinoma.
Stephan Braun, Paul McSheehy, Karine Litherland, Phil McKernan, Nicole Forster-Gross, Felix Bachmann

Expert Opin Investig Drugs· November 2021

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Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).
Vassilis Genoud, Felipe I Espinoza, Eliana Marinari, Viviane Rochemont, Pierre-Yves Dietrich, Felix Bachmann

JCI Insight· September 2021

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Probing the Effects of the FGFR-Inhibitor Derazantinib on Vascular Development in Zebrafish Embryos.
Maria P Kotini, Felix Bachmann, Jochen Spickermann, Paul M McSheehy, Markus Affolter

Pharmaceuticals (Basel)· December 2020

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Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours.
Rebecca Kristeleit, Jeffry Evans, L Rhoda Molife, Nina Tunariu, Heather Shaw, Felix Bachmann

Br J Cancer· October 2020

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EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis.
Raphaël Bergès, Aurélie Tchoghandjian, Arnauld Sergé, Stéphane Honoré, Dominique Figarella-Branger, Felix Bachmann

Oncotarget· February 2020

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High-speed motility originates from cooperatively pushing and pulling flagella bundles in bilophotrichous bacteria.
Klaas Bente, Sarah Mohammadinejad, Mohammad Avalin Charsooghi, Felix Bachmann, Agnese Codutti

Elife· January 2020

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Bead-Based Hydrodynamic Simulations of Rigid Magnetic Micropropellers.
Agnese Codutti, Felix Bachmann, Damien Faivre, Stefan Klumpp

Front Robot AI· September 2018

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Detection of circulating tumour cell clusters in human glioblastoma.
Ilona Krol, Francesc Castro-Giner, Martina Maurer, Sofia Gkountela, Barbara Maria Szczerba, Felix Bachmann

Br J Cancer· August 2018

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Biohybrid and Bioinspired Magnetic Microswimmers.
Klaas Bente, Agnese Codutti, Felix Bachmann, Damien Faivre

Small· May 2018

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The novel microtubule targeting agent BAL101553 in combination with radiotherapy in treatment-refractory tumor models.
Ashish Sharma, Angela Broggini-Tenzer, Van Vuong, Alessandra Messikommer, Katarzyna J Nytko, Felix Bachmann

Radiother Oncol· September 2017

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Active sites in heterogeneous ice nucleation-the example of K-rich feldspars.
Alexei Kiselev, Felix Bachmann, Philipp Pedevilla, Stephen J Cox, Angelos Michaelides

Science· January 2017

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The Novel Tubulin-Binding Checkpoint Activator BAL101553 Inhibits EB1-Dependent Migration and Invasion and Promotes Differentiation of Glioblastoma Stem-like Cells.
Raphaël Bergès, Aurélie Tchoghandjian, Stéphane Honoré, Marie-Anne Estève, Dominique Figarella-Branger, Felix Bachmann

Mol Cancer Ther· November 2016

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eIF3a is over-expressed in urinary bladder cancer and influences its phenotype independent of translation initiation.
Rita Spilka, Christina Ernst, Helmut Bergler, Johannes Rainer, Susanne Flechsig, Felix Bachmann

Cell Oncol (Dordr)· August 2014

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The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Andrea E Prota, Franck Danel, Felix Bachmann, Katja Bargsten, Rubén M Buey

J Mol Biol· April 2014

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Overexpression of eIF3a in Squamous Cell Carcinoma of the Oral Cavity and Its Putative Relation to Chemotherapy Response.
Rita Spilka, Klaus Laimer, Felix Bachmann, Gilbert Spizzo, Alexander Vogetseder

J Oncol· August 2012

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Iron regulates hepatitis C virus translation via stimulation of expression of translation initiation factor 3.
Igor Theurl, Heinz Zoller, Peter Obrist, Christian Datz, Felix Bachmann

J Infect Dis· August 2004

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Intralesional interferon in basal cell carcinoma: how does it work?
Stanislaw Buechner, Marion Wernli, Felix Bachmann, Thomas Harr, Peter Erb

Recent Results Cancer Res· December 2002

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DCR3 locus is a predictive marker for 5-fluorouracil-based adjuvant chemotherapy in colorectal cancer.
Gabriele Mild, Felix Bachmann, Jean-Louis Boulay, Katharina Glatz, Urban Laffer

Int J Cancer· November 2002

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Tumor necrosis factor-related, apoptosis-inducing ligand supports growth of mouse mastocytoma tumors by killing tumor-infiltrating macrophages.
Alessandro Strebel, Felix Bachmann, Marion Wernli, Peter Erb

Int J Cancer· August 2002

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FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication.
Kathrin Maedler, Adriano Fontana, Frédéric Ris, Pavel Sergeev, Christian Toso, Felix Bachmann

Proc Natl Acad Sci U S A· June 2002

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