Publications by authors named "Katja Bargsten"

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Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements.
Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Katja Bargsten

Commun Biol· October 2024

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Structural insight into the stabilization of microtubules by taxanes.
Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten

Elife· March 2023

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Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Juan Estévez-Gallego, Beatriz Álvarez-Bernad, Benet Pera, Christoph Wullschleger, Olivier Raes, Katja Bargsten

Structure· January 2023

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Structural basis for Cas9 off-target activity.
Martin Pacesa, Chun-Han Lin, Antoine Cléry, Aakash Saha, Pablo R Arantes, Katja Bargsten

Cell· October 2022

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Structural Basis of Noscapine Activation for Tubulin Binding.
María A Oliva, Andrea E Prota, Javier Rodríguez-Salarichs, Youssef L Bennani, Jesús Jiménez-Barbero, Katja Bargsten

J Med Chem· August 2020

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Corrigendum: Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
Franziska M Boneberg, Tobias Brandmann, Lena Kobel, Jasmin van den Heuvel, Katja Bargsten

RNA· November 2019

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Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
Franziska M Boneberg, Tobias Brandmann, Lena Kobel, Jasmin van den Heuvel, Katja Bargsten

RNA· June 2019

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Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells.
Nataša Savić, Femke Cas Ringnalda, Christian Berk, Katja Bargsten, Jonathan Hall

Bio Protoc· January 2019

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Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.
Natasa Savic, Femke Cas Ringnalda, Helen Lindsay, Christian Berk, Katja Bargsten

Elife· May 2018

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Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.
Andrew B Waight, Katja Bargsten, Svetlana Doronina, Michel O Steinmetz, Django Sussman

PLoS One· August 2017

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Structural Basis of Microtubule Stabilization by Discodermolide.
Andrea E Prota, Katja Bargsten, Mariano Redondo-Horcajo, Amos B Smith, Chia-Ping H Yang

Chembiochem· May 2017

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Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Thomas Bohnacker, Andrea E Prota, Florent Beaufils, John E Burke, Anna Melone, Katja Bargsten

Nat Commun· March 2017

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Antivascular and antitumor properties of the tubulin-binding chalcone TUB091.
María-Dolores Canela, Sam Noppen, Oskía Bueno, Andrea E Prota, Katja Bargsten

Oncotarget· February 2017

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Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.
Chiara Trigili, Isabel Barasoain, Pedro A Sánchez-Murcia, Katja Bargsten, Mariano Redondo-Horcajo

ACS Omega· December 2016

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Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes.
Harinath Doodhi, Andrea E Prota, Ruddi Rodríguez-García, Hui Xiao, Daniel W Custar, Katja Bargsten

Curr Biol· July 2016

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Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation.
Andrea E Prota, Jocelyn Setter, Andrew B Waight, Katja Bargsten, Juan Murga

J Mol Biol· July 2016

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Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Carolin Anders, Katja Bargsten, Martin Jinek

Mol Cell· March 2016

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Fast native-SAD phasing for routine macromolecular structure determination.
Tobias Weinert, Vincent Olieric, Sandro Waltersperger, Ezequiel Panepucci, Lirong Chen, Katja Bargsten

Nat Methods· February 2015

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A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Andrea E Prota, Katja Bargsten, J Fernando Diaz, May Marsh, Carmen Cuevas

Proc Natl Acad Sci U S A· September 2014

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The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Andrea E Prota, Franck Danel, Felix Bachmann, Katja Bargsten, Rubén M Buey

J Mol Biol· April 2014

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Structural basis of microtubule stabilization by laulimalide and peloruside A.
Andrea E Prota, Katja Bargsten, Peter T Northcote, May Marsh, Karl-Heinz Altmann

Angew Chem Int Ed Engl· February 2014

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Molecular mechanism of action of microtubule-stabilizing anticancer agents.
Andrea E Prota, Katja Bargsten, Didier Zurwerra, Jessica J Field, José Fernando Díaz

Science· February 2013

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Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
Andrea E Prota, Maria M Magiera, Marijn Kuijpers, Katja Bargsten, Daniel Frey

J Cell Biol· February 2013

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Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued).
Saša Bjelić, Christian O De Groot, Martin A Schärer, Rolf Jaussi, Katja Bargsten

J Struct Biol· January 2012

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Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice.
Rubén M Buey, Renu Mohan, Kris Leslie, Thomas Walzthoeni, John H Missimer, Katja Bargsten

Mol Biol Cell· August 2011

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