Publications by authors named "Felix Wittkopp"

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Accelerating mechanistic model calibration in protein chromatography using artificial neural networks.
Dominik Voltmer, Tinu Koshy, Raena Morley, Felix Wittkopp

J Chromatogr A· July 2025

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Current state of implementation of in silico tools in the biopharmaceutical industry-Proceedings of the 5th modeling workshop.
Felix Wittkopp, John Welsh, Robert Todd, Arne Staby, David Roush

Biotechnol Bioeng· September 2024

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Anti-Langmuir elution behavior of a bispecific monoclonal antibody in cation exchange chromatography: Mechanistic modeling using a pH-dependent Self-Association Steric Mass Action isotherm.
Felix Seelinger, Felix Wittkopp, Thomas von Hirschheydt, Christian Frech

J Chromatogr A· January 2023

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Application of the Steric Mass Action formalism for modeling under high loading conditions: Part 2. Investigation of high loading and column overloading effects.
Felix Seelinger, Felix Wittkopp, Thomas von Hirschheydt, Christian Frech

J Chromatogr A· August 2022

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Application of the Steric Mass Action formalism for modeling under high loading conditions: Part 1. Investigation of the influence of pH on the steric shielding factor.
Felix Seelinger, Felix Wittkopp, Thomas von Hirschheydt, Mathias Hafner, Christian Frech

J Chromatogr A· August 2022

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Analysis of complex protein elution behavior in preparative ion exchange processes using a colloidal particle adsorption model.
Till Briskot, Tobias Hahn, Thiemo Huuk, Gang Wang, Simon Kluters, Felix Wittkopp

J Chromatogr A· September 2021

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Prediction uncertainty assessment of chromatography models using Bayesian inference.
Till Briskot, Ferdinand Stückler, Felix Wittkopp, Christopher Williams, Jessica Yang

J Chromatogr A· February 2019

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Modeling and simulation of protein elution in linear pH and salt gradients on weak, strong and mixed cation exchange resins applying an extended Donnan ion exchange model.
Felix Wittkopp, Lars Peeck, Mathias Hafner, Christian Frech

J Chromatogr A· April 2018

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Application of linear pH gradients for the modeling of ion exchange chromatography: Separation of monoclonal antibody monomer from aggregates.
Simon Kluters, Felix Wittkopp, Matthias Jöhnck, Christian Frech

J Sep Sci· February 2016

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