Publications by authors named "Ferdinand Rossi"

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Myosin Light-Chain Kinase Inhibition Potentiates the Antitumor Effects of Avapritinib in PDGFRA D842V-Mutant Gastrointestinal Stromal Tumor.
Ferdinand Rossi, Mengyuan Liu, Andrew Tieniber, Mark S Etherington, Andrew Hanna

Clin Cancer Res· June 2023

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Oncogenic KIT Modulates Type I IFN-Mediated Antitumor Immunity in GIST.
Mengyuan Liu, Mark S Etherington, Andrew Hanna, Benjamin D Medina, Gerardo A Vitiello, Ferdinand Rossi

Cancer Immunol Res· May 2021

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The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor.
Jennifer Q Zhang, Benedikt Bosbach, Jennifer K Loo, Gerardo A Vitiello, Shan Zeng, Ferdinand Rossi

Oncogene· December 2020

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Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity.
Benjamin D Medina, Mengyuan Liu, Gerardo A Vitiello, Adrian M Seifert, Shan Zeng, Ferdinand Rossi

J Exp Med· June 2019

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Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor.
Gerardo A Vitiello, Timothy G Bowler, Mengyuan Liu, Benjamin D Medina, Jennifer Q Zhang, Ferdinand Rossi

J Clin Invest· May 2019

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Macrophages and CD8 T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors.
Jennifer Q Zhang, Shan Zeng, Gerardo A Vitiello, Adrian M Seifert, Benjamin D Medina, Ferdinand Rossi

Cancer Immunol Res· April 2018

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Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor.
Gerardo A Vitiello, Benjamin D Medina, Shan Zeng, Timothy G Bowler, Jennifer Q Zhang, Ferdinand Rossi

Clin Cancer Res· February 2018

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ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor.
Shan Zeng, Adrian M Seifert, Jennifer Q Zhang, Teresa S Kim, Timothy G Bowler, Ferdinand Rossi

Oncotarget· December 2017

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Direct engagement of the PI3K pathway by mutant KIT dominates oncogenic signaling in gastrointestinal stromal tumor.
Benedikt Bosbach, Ferdinand Rossi, Yasemin Yozgat, Jennifer Loo, Jennifer Q Zhang

Proc Natl Acad Sci U S A· October 2017

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Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor.
Shan Zeng, Adrian M Seifert, Jennifer Q Zhang, Michael J Cavnar, Teresa S Kim, Ferdinand Rossi

Mol Cancer Ther· September 2017

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PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors.
Adrian M Seifert, Shan Zeng, Jennifer Q Zhang, Teresa S Kim, Noah A Cohen, Ferdinand Rossi

Clin Cancer Res· January 2017

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Pharmacological Inhibition of KIT Activates MET Signaling in Gastrointestinal Stromal Tumors.
Noah A Cohen, Shan Zeng, Adrian M Seifert, Teresa S Kim, Eric C Sorenson, Ferdinand Rossi

Cancer Res· May 2015

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Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor.
Teresa S Kim, Michael J Cavnar, Noah A Cohen, Eric C Sorenson, Jonathan B Greer, Ferdinand Rossi

Clin Cancer Res· May 2014

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KIT oncogene inhibition drives intratumoral macrophage M2 polarization.
Michael J Cavnar, Shan Zeng, Teresa S Kim, Eric C Sorenson, Lee M Ocuin, Ferdinand Rossi

J Exp Med· December 2013

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Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor.
Benedikt Bosbach, Shayu Deshpande, Ferdinand Rossi, Jae-Hung Shieh, Gunhild Sommer

Proc Natl Acad Sci U S A· August 2012

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Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.
Vinod P Balachandran, Michael J Cavnar, Shan Zeng, Zubin M Bamboat, Lee M Ocuin, Ferdinand Rossi

Nat Med· August 2011

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Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib.
Ferdinand Rossi, Yasemin Yozgat, Elisa de Stanchina, Darren Veach, Bayard Clarkson

Mol Cancer Res· September 2010

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Changes in the structure and function of ICC networks in ICC hyperplasia and gastrointestinal stromal tumors.
Joong Goo Kwon, Sung Jin Hwang, Grant W Hennig, Yulia Bayguinov, Conor McCann, Ferdinand Rossi

Gastroenterology· February 2009

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Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylate.
Ying Liu, Michelle Tseng, Sophie A Perdreau, Ferdinand Rossi, Cristina Antonescu

Cancer Res· March 2007

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Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.
Ferdinand Rossi, Imke Ehlers, Valter Agosti, Nicholas D Socci, Agnes Viale

Proc Natl Acad Sci U S A· August 2006

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Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.
Gunhild Sommer, Valter Agosti, Imke Ehlers, Ferdinand Rossi, Selim Corbacioglu

Proc Natl Acad Sci U S A· May 2003

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FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest.
Emmanuel Laplantine, Ferdinand Rossi, Malika Sahni, Claudio Basilico, David Cobrinik

J Cell Biol· August 2002

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p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development.
Ferdinand Rossi, Helen E MacLean, Wei Yuan, Richard O Francis, Ekaterina Semenova

Dev Biol· July 2002

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