Publications by authors named "Nicholas D Socci"

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Loss of tumor cell MHC class II drives MAPK inhibitor insensitivity of BRAF-mutant anaplastic thyroid cancers.
Vera Tiedje, Jillian Greenberg, Tianyue Qin, Soo-Yeon Im, Gnana P Krishnamoorthy, Nicholas D Socci

J Clin Invest· October 2025

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The Noncoding Mutational Landscape of Pancreatic Cancer Reveals Recurrent Somatic Mutations in Enhancer Regions.
Akimasa Hayashi, Yu-Jui Ho, Alvin P Makohon-Moore, Amanda Zucker, Jungeui Hong, Nicholas D Socci

Cancer Res Commun· October 2025

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Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration.
Rocio Vicario, Stamatina Fragkogianni, Maria Pokrovskii, Carina Meyer, Estibaliz Lopez-Rodrigo, Nicholas D Socci

Neuron· April 2025

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A microglia clonal inflammatory disorder in Alzheimer's disease.
Rocio Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Nicholas D Socci

Elife· March 2025

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The Evolutionary Forest of Pancreatic Cancer.
Katelyn M Mullen, Jungeui Hong, Marc A Attiyeh, Akimasa Hayashi, Hitomi Sakamoto, Nicholas D Socci

Cancer Discov· February 2025

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CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in .
Karlo Perica, Nayan Jain, Michael Scordo, Ruchi Patel, Ozgur Can Eren, Nicholas D Socci

N Engl J Med· February 2025

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Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer.
Camila Robles-Oteíza, Katherine Hastings, Jungmin Choi, Isabelle Sirois, Arvind Ravi, Nicholas D Socci

J Exp Med· January 2025

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Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors.
Sameer Farouk Sait, Kwan Ho Tang, Steven P Angus, Rebecca Brown, Daochun Sun, Nicholas D Socci

Proc Natl Acad Sci U S A· January 2025

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Loss of tumor cell MHC Class II drives insensitivity of BRAF-mutant anaplastic thyroid cancers to MAPK inhibitors.
Vera Tiedje, Jillian Greenberg, Tianyue Qin, Soo-Yeon Im, Gnana P Krishnamoorthy, Nicholas D Socci

bioRxiv· January 2025

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Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Nicholas D Socci

Nature· November 2024

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ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.
Stephanie Guillet, Tomi Lazarov, Natasha Jordan, Bertrand Boisson, Maria Tello, Nicholas D Socci

Elife· November 2024

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Author Correction: Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation.
Benjamin A Nacev, Yakshi Dabas, Matthew R Paul, Christian Pacheco, Michelle Mitchener, Nicholas D Socci

Nat Commun· October 2024

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Multiplexed Spatial Profiling of Hodgkin Reed-Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma.
Maryam Pourmaleki, Caitlin J Jones, Sabrina D Mellinghoff, Brian D Greenstein, Priyadarshini Kumar, Nicholas D Socci

Clin Cancer Res· September 2024

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A transposase-derived gene required for human brain development.
Luz Jubierre Zapater, Sara A Lewis, Rodrigo Lopez Gutierrez, Makiko Yamada, Elias Rodriguez-Fos, Nicholas D Socci

bioRxiv· August 2024

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A microglia clonal inflammatory disorder in Alzheimer's Disease.
Rocio Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Nicholas D Socci

bioRxiv· August 2024

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Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma.
Ross S Firestone, Nicholas D Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin

Blood· July 2024

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CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation.
Alvaro Quintanal-Villalonga, Kenta Kawasaki, Esther Redin, Fathema Uddin, Swanand Rakhade, Nicholas D Socci

Signal Transduct Target Ther· July 2024

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Mechanism of neurodegeneration mediated by clonal inflammatory microglia.
Rocio Vicario, Stamatina Fragkogianni, Maria Pokrovskii, Carina Mayer, Estibaliz Lopez-Rodrigo, Nicholas D Socci

bioRxiv· July 2024

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ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.
Stephanie Guillet, Tomi Lazarov, Natasha Jordan, Bertrand Boisson, Maria Tello, Nicholas D Socci

medRxiv· June 2024

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Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation.
Benjamin A Nacev, Yakshi Dabas, Matthew R Paul, Christian Pacheco, Michelle Mitchener, Nicholas D Socci

Nat Commun· June 2024

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Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Nicholas D Socci

Nature· May 2024

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Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation.
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John Slingerland, Nicholas D Socci

Cancer Immunol Res· March 2024

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Childhood cancer mutagenesis caused by transposase-derived PGBD5.
Makiko Yamada, Ross R Keller, Rodrigo Lopez Gutierrez, Daniel Cameron, Hiromichi Suzuki, Nicholas D Socci

Sci Adv· March 2024

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PDGFRβ Signaling Cooperates with β-Catenin to Modulate c-Abl and Biologic Behavior of Desmoid-Type Fibromatosis.
Jia Hu, Meera R Hameed, Narasimhan P Agaram, Karissa A Whiting, Li-Xuan Qin, Nicholas D Socci

Clin Cancer Res· January 2024

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Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse.
Susan DeWolf, Yuval Elhanati, Katherine Nichols, Nicholas R Waters, Chi L Nguyen, Nicholas D Socci

Sci Transl Med· July 2023

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