Publications by authors named "Fiona Behan"

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Benchmark Software and Data for Evaluating CRISPR-Cas9 Experimental Pipelines Through the Assessment of a Calibration Screen.
Raffaele M Iannuzzi, Ichcha Manipur, Clare Pacini, Fiona M Behan, Mario R Guarracino

CRISPR J· December 2024

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A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization.
Clare Pacini, Emma Duncan, Emanuel Gonçalves, James Gilbert, Shriram Bhosle, Fiona M Behan

Cancer Cell· February 2024

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Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Nicola A Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Fiona Behan

Nat Commun· February 2021

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Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets.
Lisa Dwane, Fiona M Behan, Emanuel Gonçalves, Howard Lightfoot, Wanjuan Yang

Nucleic Acids Res· January 2021

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Minimal genome-wide human CRISPR-Cas9 library.
Emanuel Gonçalves, Mark Thomas, Fiona M Behan, Gabriele Picco, Clare Pacini

Genome Biol· January 2021

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Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
Annie Wai Yeeng Chai, Pei San Yee, Stacey Price, Shi Mun Yee, Hui Mei Lee, Fiona M Behan

Elife· September 2020

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Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.
Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, Gabriele Picco, Fiona M Behan

Mol Syst Biol· July 2020

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Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.
Joshua M Dempster, Clare Pacini, Sasha Pantel, Fiona M Behan, Thomas Green

Nat Commun· December 2019

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Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening.
Gabriele Picco, Elisabeth D Chen, Luz Garcia Alonso, Fiona M Behan, Emanuel Gonçalves

Nat Commun· May 2019

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Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Fiona M Behan, Francesco Iorio, Gabriele Picco, Emanuel Gonçalves, Charlotte M Beaver

Nature· April 2019

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JACKS: joint analysis of CRISPR/Cas9 knockout screens.
Felicity Allen, Fiona Behan, Anton Khodak, Francesco Iorio, Kosuke Yusa

Genome Res· March 2019

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Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects.
Emanuel Gonçalves, Fiona M Behan, Sandra Louzada, Damien Arnol, Euan A Stronach

Genome Biol· February 2019

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Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting.
Francesco Iorio, Fiona M Behan, Emanuel Gonçalves, Shriram G Bhosle, Elisabeth Chen

BMC Genomics· August 2018

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siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth.
Shane P Duggan, Catherine Garry, Fiona M Behan, Sinead Phipps, Hiromi Kudo

Cell Mol Gastroenterol Hepatol· January 2018

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Corrigendum: The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.
Shane P Duggan, Fiona M Behan, Murat Kirca, Abdul Zaheer, Sarah A McGarrigle

Sci Rep· October 2016

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The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.
Shane P Duggan, Fiona M Behan, Murat Kirca, Abdul Zaheer, Sarah A McGarrigle

Sci Rep· September 2016

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An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels.
Shane P Duggan, Fiona M Behan, Murat Kirca, Sinead Smith, John V Reynolds

Carcinogenesis· May 2010

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