Publications by authors named "Frances Sladek"

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P2-HNF4α alters linoleic acid metabolism and mitigates soybean oil-induced obesity: role for oxylipins.
Poonamjot Deol, Johannes Fahrmann, Dmitry Grapov, Jun Yang, Jane R Evans, Frances M Sladek

J Lipid Res· December 2025

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The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors.
Stephen P H Alexander, John A Cidlowski, Alasdair J Gibb, Eamonn Kelly, Alistair A Mathie, Frances Sladek

Br J Pharmacol· December 2025

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Editorial: Hepatocyte nuclear factor 4 alpha - new insights into an old receptor.
Frances M Sladek, Udayan Apte, Poonamjot Deol

Front Endocrinol (Lausanne)· October 2024

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HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver.
Jonathan R Deans, Poonamjot Deol, Nina Titova, Sarah H Radi, Linh M Vuong, Frances M Sladek

Front Endocrinol (Lausanne)· January 2024

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Impact of various high fat diets on gene expression and the microbiome across the mouse intestines.
Jose Martinez-Lomeli, Poonamjot Deol, Jonathan R Deans, Tao Jiang, Paul Ruegger, Frances M Sladek

Sci Rep· December 2023

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Impact of Various High Fat Diets on Gene Expression and the Microbiome Across the Mouse Intestines.
Jose Martinez-Lomeli, Poonamjot Deol, Jonathan R Deans, Tao Jiang, Paul Ruegger, Frances M Sladek

Res Sq· October 2023

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HNF4α isoforms: the fraternal twin master regulators of liver function.
Sarah H Radi, Kiranmayi Vemuri, Jose Martinez-Lomeli, Frances M Sladek

Front Endocrinol (Lausanne)· August 2023

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Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine.
Kiranmayi Vemuri, Sarah H Radi, Frances M Sladek, Michael P Verzi

Front Endocrinol (Lausanne)· August 2023

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Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice.
Poonamjot Deol, Paul Ruegger, Geoffrey D Logan, Ali Shawki, Jiang Li, Frances M Sladek

Gut Microbes· July 2023

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Hepatic circadian and differentiation factors control liver susceptibility for fatty liver disease and tumorigenesis.
Baharan Fekry, Aleix Ribas-Latre, Rachel Van Drunen, Rafael Bravo Santos, Samay Shivshankar, Frances M Sladek

FASEB J· September 2022

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Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation.
Dongmei Bai, Yong Wu, Poonamjot Deol, Yumiko Nobumori, Qi Zhou, Frances M Sladek

Cancer Lett· January 2021

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Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice.
Poonamjot Deol, Elena Kozlova, Matthew Valdez, Catherine Ho, Ei-Wen Yang, Frances M Sladek

Endocrinology· February 2020

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HNF4α-Deficient Fatty Liver Provides a Permissive Environment for Sex-Independent Hepatocellular Carcinoma.
Baharan Fekry, Aleix Ribas-Latre, Corrine Baumgartner, Alaa M T Mohamed, Mikhail G Kolonin, Frances M Sladek

Cancer Res· November 2019

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Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver.
Poonamjot Deol, Jun Yang, Christophe Morisseau, Bruce D Hammock, Frances M Sladek

Front Pharmacol· May 2019

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Conservation of DNA and ligand binding properties of retinoid X receptor from the placozoan Trichoplax adhaerens to human.
Adam M Reitzel, Jason Macrander, Daniel Mane-Padros, Bin Fang, Frances M Sladek

J Steroid Biochem Mol Biol· November 2018

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Incompatibility of the circadian protein BMAL1 and HNF4α in hepatocellular carcinoma.
Baharan Fekry, Aleix Ribas-Latre, Corrine Baumgartner, Jonathan R Deans, Christopher Kwok, Frances M Sladek

Nat Commun· October 2018

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Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice.
Poonamjot Deol, Johannes Fahrmann, Jun Yang, Jane R Evans, Antonia Rizo, Frances M Sladek

Sci Rep· October 2017

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Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs.
Michael Allevato, Eugene Bolotin, Mark Grossman, Daniel Mane-Padros, Frances M Sladek

PLoS One· September 2017

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Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.
Karthikeyani Chellappa, Poonamjot Deol, Jane R Evans, Linh M Vuong, Gang Chen, Frances M Sladek

Elife· May 2016

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Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.
Linh M Vuong, Karthikeyani Chellappa, Joseph M Dhahbi, Jonathan R Deans, Bin Fang, Frances M Sladek

Mol Cell Biol· October 2015

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The transcription factor encyclopedia.
Dimas Yusuf, Stefanie L Butland, Magdalena I Swanson, Eugene Bolotin, Amy Ticoll, Frances M Sladek

Genome Biol· September 2012

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The yin and yang of proliferation and differentiation: cyclin D1 inhibits differentiation factors ChREBP and HNF4α.
Frances M Sladek

Cell Cycle· September 2012

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Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.
Bin Fang, Daniel Mane-Padros, Eugene Bolotin, Tao Jiang, Frances M Sladek

Nucleic Acids Res· July 2012

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HNF4α: a new biomarker in colon cancer?
Karthikeyani Chellappa, Graham R Robertson, Frances M Sladek

Biomark Med· June 2012

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