Publications by authors named "Francesca M Buffa"

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Systems Biology and Functional Assessments of Human iPSC-Cardiomyocyte Models of Insulin Resistance Capture Key Hallmarks of Diabetic Cardiomyopathy.
Ryan D Carter, Ujang Purnama, Marcos Castro-Guarda, Claudia N Montes-Aparicio, Anandhakumar Chandran, Francesca M Buffa

Diabetes· November 2025

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GeneFEAST: the pivotal, gene-centric step in functional enrichment analysis interpretation.
Avigail Taylor, Valentine M Macaulay, Matthieu J Miossec, Anand K Maurya, Francesca M Buffa

Bioinformatics· March 2025

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Defining hypoxia in cancer: A landmark evaluation of hypoxia gene expression signatures.
Matteo Di Giovannantonio, Fiona Hartley, Badran Elshenawy, Alessandro Barberis, Dan Hudson, Francesca M Buffa

Cell Genom· February 2025

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Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors.
Enric Domingo, Sanjay Rathee, Andrew Blake, Leslie Samuel, Graeme Murray, Francesca M Buffa

EBioMedicine· August 2024

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Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair.
Hongbin Yang, Shahd Fouad, Paul Smith, Eun Young Bae, Yu Ji, Francesca M Buffa

Sci Adv· August 2024

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Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic disease.
Philip Vincent Charlton, Dawn O'Reilly, Yiannis Philippou, Srinivasa Rao Rao, Alastair David Gordon Lamb, Francesca Meteora Buffa

Prostate· July 2024

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Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures.
Umair Mahmood, Andrew Blake, Sanjay Rathee, Leslie Samuel, Graeme Murray, Francesca M Buffa

Cancer Res Commun· July 2024

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Metabolic symbiosis between oxygenated and hypoxic tumour cells: An agent-based modelling study.
Pahala Gedara Jayathilake, Pedro Victori, Clara E Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Francesca M Buffa

PLoS Comput Biol· March 2024

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New role of fat-free mass in cancer risk linked with genetic predisposition.
Benjamin H L Harris, Matteo Di Giovannantonio, Ping Zhang, David A Harris, Simon R Lord, Francesca M Buffa

Sci Rep· March 2024

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Antitumour effect of the mitochondrial complex III inhibitor Atovaquone in combination with anti-PD-L1 therapy in mouse cancer models.
Gonzalo Rodriguez-Berriguete, Rathi Puliyadi, Nicole Machado, Alessandro Barberis, Remko Prevo, Francesca M Buffa

Cell Death Dis· January 2024

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Robustness and reproducibility for AI learning in biomedical sciences: RENOIR.
Alessandro Barberis, Hugo J W L Aerts, Francesca M Buffa

Sci Rep· January 2024

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A machine learning and directed network optimization approach to uncover regulatory patterns.
Charalampos P Triantafyllidis, Alessandro Barberis, Fiona Hartley, Ana Miar Cuervo, Enio Gjerga, Francesca M Buffa

iScience· December 2023

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MAGNETO: Cell type marker panel generator from single-cell transcriptomic data.
Andrea Tangherloni, Simone G Riva, Brynelle Myers, Francesca M Buffa, Paolo Cazzaniga

J Biomed Inform· November 2023

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The impact of survivorship bias in glioblastoma research.
Francesco Pasqualetti, Alessandro Barberis, Sofia Zanotti, Nicola Montemurro, Gian Luca De Salvo, Francesca M Buffa

Crit Rev Oncol Hematol· August 2023

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WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.
Nicholas Coupe, Lina Guo, Esther Bridges, Leticia Campo, Olivia Espinosa, Francesca M Buffa

Cell Oncol (Dordr)· April 2023

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Single cell RNA-sequencing: A powerful yet still challenging technology to study cellular heterogeneity.
May Ke, Badran Elshenawy, Helen Sheldon, Anjali Arora, Francesca M Buffa

Bioessays· November 2022

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New perspectives in liquid biopsy for glioma patients.
Francesco Pasqualetti, Milena Rizzo, Sara Franceschi, Francesca Lessi, Fabiola Paiar, Francesca M Buffa

Curr Opin Oncol· November 2022

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Machine Learning Using Gene-Sets to Infer miRNA Function.
Andrew Dhawan, Francesca M Buffa

Adv Exp Med Biol· November 2022

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Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.
Zhuoyao Chen, Rafael M Ioris, Stacey Richardson, Ava N Van Ess, Iolanda Vendrell, Francesca M Buffa

Cell Death Differ· October 2022

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The MITF regulatory network in melanoma.
Jagat S Chauhan, Michael Hölzel, Jean-Philippe Lambert, Francesca M Buffa, Colin R Goding

Pigment Cell Melanoma Res· September 2022

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Obesity: a perfect storm for carcinogenesis.
Benjamin H L Harris, Valentine M Macaulay, David A Harris, Paul Klenerman, Fredrik Karpe, Francesca M Buffa

Cancer Metastasis Rev· September 2022

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Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.
Christos E Zois, Anne M Hendriks, Syed Haider, Elisabete Pires, Esther Bridges, Francesca M Buffa

Cell Death Dis· June 2022

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ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression.
Helen Sheldon, Esther Bridges, Ildefonso Silva, Massimo Masiero, David M Favara, Francesca M Buffa

Mol Cancer Res· November 2021

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Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity.
Samuel B Bader, Tiffany S Ma, Charlotte J Simpson, Jiachen Liang, Sakura Eri B Maezono, Francesca M Buffa

Nucleic Acids Res· July 2021

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Hypoxia-induced SETX links replication stress with the unfolded protein response.
Shaliny Ramachandran, Tiffany S Ma, Jon Griffin, Natalie Ng, Iosifina P Foskolou, Francesca M Buffa

Nat Commun· June 2021

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