Publications by authors named "Francesco Ramirez"

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Fibrillin-1 Deficiency Perturbs Aortic Cholinergic Relaxation and Adrenergic Contraction in a Mouse Model of Early Onset Progressively Severe Marfan Syndrome.
Anna Cantalupo, Keiichi Asano, Sergey Dikalov, Dylan Gordon, Francesco Ramirez

J Vasc Res· August 2025

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Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells.
Yifei Sun, Keiichi Asano, Lauriane Sedes, Anna Cantalupo, Jens Hansen, Francesco Ramirez

JCI Insight· May 2023

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Fibrillin-1 deficiency in the outer perichondrium causes longitudinal bone overgrowth in mice with Marfan syndrome.
Lauriane Sedes, Elisa Wondimu, Brittany Crockett, Jens Hansen, Anna Cantalupo, Francesco Ramirez

Hum Mol Genet· September 2022

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The Multiple Functions of Fibrillin-1 Microfibrils in Organismal Physiology.
Keiichi Asano, Anna Cantalupo, Lauriane Sedes, Francesco Ramirez

Int J Mol Sci· February 2022

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The role of LTBPs in TGF beta signaling.
Daniel Rifkin, Nalani Sachan, Karan Singh, Elyse Sauber, George Tellides, Francesco Ramirez

Dev Dyn· January 2022

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Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome.
Keiichi Asano, Anna Cantalupo, Lauriane Sedes, Francesco Ramirez

Biomolecules· January 2022

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Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.
Cristina I Caescu, Jens Hansen, Brittany Crockett, Wenzhen Xiao, Pauline Arnaud, Francesco Ramirez

Arterioscler Thromb Vasc Biol· September 2021

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The influence of fibrillin-1 and physical activity upon tendon tissue morphology and mechanical properties in mice.
Peter H T Tran, Tanja Skrba, Elisabeth Wondimu, Giuseppina Galatioto, René Brüggebusch Svensson, Francesco Ramirez

Physiol Rep· November 2019

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Extracellular Determinants of Arterial Morphogenesis, Growth, and Homeostasis.
Robert P Mecham, Francesco Ramirez

Curr Top Dev Biol· July 2019

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Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms.
Jens Hansen, Josephine Galatioto, Cristina I Caescu, Pauline Arnaud, Rhodora C Calizo, Francesco Ramirez

JCI Insight· June 2019

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Therapies for Thoracic Aortic Aneurysms and Acute Aortic Dissections.
Dianna M Milewicz, Francesco Ramirez

Arterioscler Thromb Vasc Biol· February 2019

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Marfan syndrome; A connective tissue disease at the crossroads of mechanotransduction, TGFβ signaling and cell stemness.
Francesco Ramirez, Cristina Caescu, Elisabeth Wondimu, Josephine Galatioto

Matrix Biol· October 2018

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Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease-Brief Report.
Josephine Galatioto, Cristina I Caescu, Jens Hansen, Jason R Cook, Irving Miramontes, Francesco Ramirez

Arterioscler Thromb Vasc Biol· March 2018

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Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.
Frank S Cikach, Christopher D Koch, Timothy J Mead, Josephine Galatioto, Belinda B Willard, Francesco Ramirez

JCI Insight· March 2018

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Fibrillin microfibrils in bone physiology.
Silvia Smaldone, Francesco Ramirez

Matrix Biol· December 2017

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Fibrillin-1 microfibrils influence adult bone marrow hematopoiesis.
Silvia Smaldone, Carolina L Bigarella, Maria Del Solar, Saghi Ghaffari, Francesco Ramirez

Matrix Biol· December 2017

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Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models.
Dianna M Milewicz, Siddharth K Prakash, Francesco Ramirez

Annu Rev Med· January 2017

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Losartan Attenuates Degradation of Aorta and Lung Tissue Micromechanics in a Mouse Model of Severe Marfan Syndrome.
Jia-Jye Lee, Josephine Galatioto, Satish Rao, Francesco Ramirez, Kevin D Costa

Ann Biomed Eng· October 2016

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Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche.
Silvia Smaldone, Nicholas P Clayton, Maria del Solar, Gemma Pascual, Seng H Cheng, Francesco Ramirez

J Bone Miner Res· January 2016

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Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.
Lior Zilberberg, Colin K L Phoon, Ian Robertson, Branka Dabovic, Francesco Ramirez

Proc Natl Acad Sci U S A· November 2015

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Introduction to the mini-review series "Extracellular determinants of cell signaling".
Francesco Ramirez

Matrix Biol· September 2015

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Tendon functional extracellular matrix.
Hazel R C Screen, David E Berk, Karl E Kadler, Francesco Ramirez, Marian F Young

J Orthop Res· June 2015

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Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice.
Gerhard Sengle, Valerie Carlberg, Sara F Tufa, Noe L Charbonneau, Silvia Smaldone, Francesco Ramirez

PLoS Genet· June 2015

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Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.
Jason R Cook, Nicholas P Clayton, Luca Carta, Josephine Galatioto, Emily Chiu, Francesco Ramirez

Arterioscler Thromb Vasc Biol· April 2015

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Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome.
Jason R Cook, Luca Carta, Ludovic Bénard, Elie R Chemaly, Emily Chiu, Francesco Ramirez

J Clin Invest· March 2014

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