Publications by authors named "Frank Hahn"

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The Relationship between Substrate Structure and Selectivity of Ketoreduction in Multimodular Polyketide Synthases: A Comparative Study of A-Type Ketoreductases from Late Modules Using Complex Precursor Analogues.
Lisa N K T Nguyen, Sebastian Derra, Frank Hahn

ACS Chem Biol· January 2025

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Rieske Oxygenase-Catalyzed Oxidative Late-Stage Functionalization during Complex Antifungal Polyketide Biosynthesis.
Florian M Guth, Frederick Lindner, Simon Rydzek, Andreas Peil, Steffen Friedrich, Frank Hahn

ACS Chem Biol· December 2023

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Towards understanding oxygen heterocycle-forming biocatalysts: a selectivity study of the pyran synthase PedPS7.
Lisa Wagner, Jörg Stang, Sebastian Derra, Tim Hollmann, Frank Hahn

Org Biomol Chem· December 2022

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Studying a Bottleneck of Multimodular Polyketide Synthase Processing: the Polyketide Structure-Dependent Performance of Ketoreductase Domains.
Marius Schröder, Theresa Roß, Franziska Hemmerling, Frank Hahn

ACS Chem Biol· May 2022

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Cross-linking of a polyketide synthase domain leads to a recyclable biocatalyst for chiral oxygen heterocycle synthesis.
Lisa Wagner, Theresa Roß, Tim Hollmann, Frank Hahn

RSC Adv· June 2021

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The ambruticins and jerangolids - chemistry, biology and chemoenzymatic synthesis of potent antifungal drug candidates.
Frank Hahn, Florian M Guth

Nat Prod Rep· October 2020

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Step-Economic Synthesis of Biomimetic β-Ketopolyene Thioesters and Demonstration of Their Usefulness in Enzymatic Biosynthesis Studies.
Johannes Wunderlich, Theresa Roß, Marius Schröder, Frank Hahn

Org Lett· July 2020

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Total Synthesis of Complex Biosynthetic Late-Stage Intermediates and Bioconversion by a Tailoring Enzyme from Jerangolid Biosynthesis.
Frederick Lindner, Steffen Friedrich, Frank Hahn

J Org Chem· November 2018

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An Unusual Fatty Acyl:Adenylate Ligase (FAAL)-Acyl Carrier Protein (ACP) Didomain in Ambruticin Biosynthesis.
Franziska Hemmerling, Karen E Lebe, Johannes Wunderlich, Frank Hahn

Chembiochem· May 2018

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Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain.
Kwang Hoon Sung, Gesche Berkhan, Tim Hollmann, Lisa Wagner, Wulf Blankenfeldt, Frank Hahn

Angew Chem Int Ed Engl· January 2018

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The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis.
Gesche Berkhan, Christian Merten, Claudia Holec, Frank Hahn

Angew Chem Int Ed Engl· October 2016

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Characterisation of the Broadly-Specific O-Methyl-transferase JerF from the Late Stages of Jerangolid Biosynthesis.
Steffen Friedrich, Franziska Hemmerling, Frederick Lindner, Anna Warnke, Johannes Wunderlich, Frank Hahn

Molecules· October 2016

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Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides.
Franziska Hemmerling, Frank Hahn

Beilstein J Org Chem· August 2016

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A dehydratase domain in ambruticin biosynthesis displays additional activity as a pyran-forming cyclase.
Gesche Berkhan, Frank Hahn

Angew Chem Int Ed Engl· December 2014

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Synthesis of complex intermediates for the study of a dehydratase from borrelidin biosynthesis.
Frank Hahn, Nadine Kandziora, Steffen Friedrich, Peter Francis Leadlay

Beilstein J Org Chem· April 2014

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Unusual acetylation-elimination in the formation of tetronate antibiotics.
Chompoonik Kanchanabanca, Weixin Tao, Hui Hong, Yajing Liu, Frank Hahn

Angew Chem Int Ed Engl· May 2013

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Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry.
Daniel Fürniss, Timo Mack, Frank Hahn, Sidonie B L Vollrath, Katarzyna Koroniak

Beilstein J Org Chem· February 2013

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Merging chemical synthesis and biosynthesis: a new chapter in the total synthesis of natural products and natural product libraries.
Andreas Kirschning, Frank Hahn

Angew Chem Int Ed Engl· April 2012

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The Impact of Breast Care Nurses on Patients' Satisfaction, Understanding of the Disease, and Adherence to Adjuvant Endocrine Therapy.
Ute-Susann Albert, Cosima Zemlin, Peymann Hadji, Volker Ziller, Barbara Kuhler, Birgit Frank-Hahn

Breast Care (Basel)· June 2011

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Stereoselectivity of isolated dehydratase domains of the borrelidin polyketide synthase: implications for cis double bond formation.
Olivia Vergnolle, Frank Hahn, Abel Baerga-Ortiz, Peter F Leadlay, Jennifer N Andexer

Chembiochem· May 2011

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In vitro reconstruction of tetronate RK-682 biosynthesis.
Yuhui Sun, Frank Hahn, Yuliya Demydchuk, James Chettle, Manuela Tosin

Nat Chem Biol· February 2010

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Versatile procedure for asymmetric and orthogonal protection of symmetric polyamines and its advantages for solid phase synthesis.
Frank Hahn, Ute Schepers

J Comb Chem· August 2008

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Conjugation of spermine facilitates cellular uptake and enhances antitumor and antibiotic properties of highly lipophilic porphyrins.
Frank Hahn, Katja Schmitz, Teodor S Balaban, Stefan Bräse, Ute Schepers

ChemMedChem· August 2008

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