Publications by authors named "Frank Lowery"

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Facts and Hopes for Neoantigen-Enriched TIL.
Siqi C Brough, Kristen L Skonieczny, Stav Leibou, Frank J Lowery, Stephanie L Goff

Clin Cancer Res· December 2025

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Identification of HLA class II-restricted T cell receptors against shared PIK3CA mutations in patients with epithelial cancers.
S M Rafiqul Islam, Samantha Seitter, Maria Parkhurst, Frank J Lowery, Miaki Fukuhara

Cancer Immunol Immunother· December 2025

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A pan-cancer comparative analysis of the cancer genome atlas transcriptomic TIL-immune signatures.
Kyle J Hitscherich, Darryl Nousome, Aaron J Dinerman, Victoria Dulemba, Frank J Lowery

Cancer Immunol Immunother· August 2025

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A platform for multisite immune profiling of premetastatic pancreatic cancer at single-cell resolution.
Elishama N Kanu, Ashley A Fletcher, Jiayin Bao, Ethan S Agritelley, Julia Button, Frank J Lowery

Cancer Immunol Immunother· August 2025

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Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial.
Frank J Lowery, Stephanie L Goff, Billel Gasmi, Maria R Parkhurst, Nivedita M Ratnam

Nat Med· June 2025

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Publisher Correction: Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial.
Frank J Lowery, Stephanie L Goff, Billel Gasmi, Maria R Parkhurst, Nivedita M Ratnam

Nat Med· June 2025

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Rapid enrichment of progenitor exhausted neoantigen-specific CD8 T cells from peripheral blood.
Mamduh Khateb, Raina Jung, Stav Leibou, Patrick Hadley, Zhiya Yu, Frank Lowery

bioRxiv· May 2025

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A Pan-Cancer Comparative Analysis of The Cancer Genome Atlas Transcriptomic TIL-Immune Signatures.
Kyle Hitscherich, Darryl Noussome, Aaron Dinerman, Victoria Dulemba, Frank Lowery

Res Sq· April 2025

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Utilization of primary tumor samples for cancer neoantigen discovery.
Vid Leko, Eric Groh, Shoshana T Levi, Amy R Copeland, Bradley Sinclair White, Frank J Lowery

J Immunother Cancer· January 2025

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Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition.
Arseniy E Yuzhalin, Frank J Lowery, Yohei Saito, Xiangliang Yuan, Jun Yao

Nat Cell Biol· October 2024

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Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results.
Maria Parkhurst, Stephanie L Goff, Frank J Lowery, Rachel K Beyer, Hyunmi Halas

Nat Med· September 2024

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Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes.
Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Zhiya Yu, Frank J Lowery

J Immunother Cancer· May 2024

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Phenotypic signatures of circulating neoantigen-reactive CD8 T cells in patients with metastatic cancers.
Rami Yossef, Sri Krishna, Sivasish Sindiri, Frank J Lowery, Amy R Copeland

Cancer Cell· December 2023

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Cell surface marker-based capture of neoantigen-reactive CD8 T-cell receptors from metastatic tumor digests.
Praveen D Chatani, Frank J Lowery, Neilesh B Parikh, Kyle J Hitscherich, Rami Yossef

J Immunother Cancer· May 2023

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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Douglas C Palmer, Beau R Webber, Yogin Patel, Matthew J Johnson, Christine M Kariya, Frank J Lowery

Med· October 2022

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Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Sanghyun P Kim, Nolan R Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Frank J Lowery

Cancer Immunol Res· August 2022

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Neoantigen Identification and Response to Adoptive Cell Transfer in Anti-PD-1 Naïve and Experienced Patients with Metastatic Melanoma.
Shoshana T Levi, Amy R Copeland, Shirley Nah, Jessica S Crystal, Gabriel D Ivey, Frank Lowery

Clin Cancer Res· July 2022

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A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Ken-Ichi Hanada, Chihao Zhao, Raul Gil-Hoyos, Jared J Gartner, Christopher Chow-Parmer, Frank J Lowery

Cancer Cell· May 2022

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Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers.
Frank J Lowery, Sri Krishna, Rami Yossef, Neilesh B Parikh, Praveen D Chatani

Science· February 2022

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Identification and Validation of T-cell Receptors Targeting Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy.
Noam Levin, Biman C Paria, Nolan R Vale, Rami Yossef, Frank J Lowery

Clin Cancer Res· September 2021

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Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing.
Yong-Chen Lu, Zhili Zheng, Frank J Lowery, Jared J Gartner, Todd D Prickett

J Immunother Cancer· July 2021

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Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells.
Biman C Paria, Noam Levin, Frank J Lowery, Anna Pasetto, Drew C Deniger

J Immunother· January 2021

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Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer.
Sri Krishna, Frank J Lowery, Amy R Copeland, Erol Bahadiroglu, Ratnadeep Mukherjee

Science· December 2020

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mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer.
Gal Cafri, Jared J Gartner, Tal Zaks, Kristen Hopson, Noam Levin, Frank J Lowery

J Clin Invest· November 2020

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Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Parisa Malekzadeh, Rami Yossef, Gal Cafri, Biman C Paria, Frank J Lowery

Clin Cancer Res· March 2020

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