Publications by authors named "Frank Runge"

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Range of Neurological Signs in Cynomolgus Monkeys After Intrathecal Bolus Administration of Antisense Oligonucleotides.
Sven Korte, Frank Runge, Magdalena M Wozniak, Florian T Ludwig, Daniela Smieja

Int J Toxicol· September 2021

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Save Your Maximum Tolerated Dose: How to Diagnose Procedure-Related Spinal Cord Lesions After Lumbar Intrathecal Bolus Administration of Oligonucleotides in Cynomolgus Monkeys.
Sven Korte, Jorge Luft, Anne von Keutz, Frank Runge, Lars Mecklenburg

Int J Toxicol· September 2021

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Acoustic Ejection Mass Spectrometry: A Fully Automatable Technology for High-Throughput Screening in Drug Discovery.
Roman P Simon, Tim T Häbe, Robert Ries, Martin Winter, Yuting Wang, Frank Runge

SLAS Discov· September 2021

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MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein-Ligand Interactions at High Throughput.
Roman P Simon, Martin Winter, Carola Kleiner, Lucie Wehrle, Michael Karnath, Frank Runge

SLAS Discov· January 2021

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Quantification of Drugs in Distinctly Separated Ocular Substructures of Albino and Pigmented Rats.
Anna-Kaisa Rimpelä, Michel Garneau, Katja S Baum-Kroker, Tanja Schönberger, Frank Runge

Pharmaceutics· December 2020

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Ultrahigh-Throughput ESI-MS: Sampling Pushed to Six Samples per Second by Acoustic Ejection Mass Spectrometry.
Tim T Häbe, Chang Liu, Tom R Covey, Roman P Simon, Wolfgang Reindl, Frank Runge

Anal Chem· September 2020

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In-Depth Characterization of EpiIntestinal Microtissue as a Model for Intestinal Drug Absorption and Metabolism in Human.
Yunhai Cui, Stephanie Claus, David Schnell, Frank Runge, Caroline MacLean

Pharmaceutics· April 2020

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Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond.
Andreas Zeller, Alessandro Brigo, Andreas Brink, Melanie Guerard, Dieter Lang, Frank Runge

Chem Res Toxicol· January 2020

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The Novel Phosphodiesterase 9A Inhibitor BI 409306 Increases Cyclic Guanosine Monophosphate Levels in the Brain, Promotes Synaptic Plasticity, and Enhances Memory Function in Rodents.
Holger Rosenbrock, Riccardo Giovannini, Gerhard Schänzle, Eliza Koros, Frank Runge

J Pharmacol Exp Ther· December 2019

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A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory Guidance.
Simone Schadt, Bojan Bister, Swapan K Chowdhury, Christoph Funk, Cornelis E C A Hop, Frank Runge

Drug Metab Dispos· June 2018

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Relative bioavailability of an empagliflozin 25-mg/linagliptin 5-mg fixed-dose combination tablet
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Stephan Glund, Michaela Mattheus, Frank Runge, Peter Rose, Christian Friedrich

Int J Clin Pharmacol Ther· April 2017

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A phase I, randomized, proof-of-clinical-mechanism study assessing the pharmacokinetics and pharmacodynamics of the oral PDE9A inhibitor BI 409306 in healthy male volunteers.
Katja Boland, Viktoria Moschetti, Chantaratsamon Dansirikul, Solen Pichereau, Lien Gheyle, Frank Runge

Hum Psychopharmacol· January 2017

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Toxicity profile of the GATA-3-specific DNAzyme hgd40 after inhalation exposure.
Rainer Fuhst, Frank Runge, Jochen Buschmann, Heinrich Ernst, Christiane Praechter

Pulm Pharmacol Ther· April 2013

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Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy.
Lyubov Chaykovska, Karoline von Websky, Jan Rahnenführer, Markus Alter, Susi Heiden, Frank Runge

PLoS One· April 2012

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Excretion of the dipeptidyl peptidase-4 inhibitor linagliptin in rats is primarily by biliary excretion and P-gp-mediated efflux.
Holger Fuchs, Frank Runge, Heinz-Dieter Held

Eur J Pharm Sci· April 2012

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Particle deposition in the lung of the Göttingen minipig.
Horst Windt, Heiko Kock, Frank Runge, Ulrich Hübel, Wolfgang Koch

Inhal Toxicol· August 2010

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Characterization of lycopene nanoparticles combining solid-state and suspended-state NMR spectroscopy.
Jürgen Wegmann, Manfred Krucker, Stefan Bachmann, Gerd Fischer, Daniel Zeeb, Frank Runge

J Agric Food Chem· December 2002

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Photoprotective potential of lycopene, beta-carotene, vitamin E, vitamin C and carnosic acid in UVA-irradiated human skin fibroblasts.
Elizabeth A Offord, Jean-Charles Gautier, Ornella Avanti, Corinne Scaletta, Frank Runge

Free Radic Biol Med· June 2002

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