Publications by authors named "Fraser Hof"

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I
Information-rich sensors by assembly: a review on the use of macrocyclic hosts in the context of complex chemical systems.
Allison J Selinger, Fraser Hof

Chem Commun (Camb)· October 2025

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Pharmacological targeting of CBX7 alters the epigenetic landscape and induces differentiation of leukemic cells.
Anne P de Groot, Chelsea R Wilson, Ellen Weersing, Jacobine S Pouw, Albertina Dethmers-Ausema, Fraser Hof

Blood Neoplasia· December 2024

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Extended Sulfo-Pillar[6]arenes ─ a New Host Family and Its Application in the Binding of Direct Oral Anticoagulants.
Chelsea R Wilson, Austia O Puckett, Isabella M Murray, Allen G Oliver, Fraser Hof

J Am Chem Soc· October 2024

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De novo synthetic antimicrobial peptide design with a recurrent neural network.
Chenkai Li, Darcy Sutherland, Amelia Richter, Lauren Coombe, Anat Yanai, Fraser Hof

Protein Sci· August 2024

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Mixed host co-assembled systems for broad-scope analyte sensing.
Allison J Selinger, Joana Krämer, Eric Poarch, Dennis Hore, Frank Biedermann, Fraser Hof

Chem Sci· August 2024

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Adaptive Supramolecular Networks: Emergent Sensing from Complex Systems.
Allison J Selinger, Fraser Hof

Angew Chem Int Ed Engl· November 2023

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Associating Biological Activity and Predicted Structure of Antimicrobial Peptides from Amphibians and Insects.
Amelia Richter, Darcy Sutherland, Hossein Ebrahimikondori, Alana Babcock, Nathan Louie, Fraser Hof

Antibiotics (Basel)· November 2022

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Molecular recognition of methylated amino acids and peptides by Pillar[6]MaxQ.
David King, Chelsea R Wilson, Lukas Herron, Chun-Lin Deng, Shams Mehdi, Fraser Hof

Org Biomol Chem· September 2022

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Binding Methylarginines and Methyllysines as Free Amino Acids: A Comparative Study of Multiple Host Classes.
Zoey Warmerdam, Bianca E Kamba, My-Hue Le, Thomas Schrader, Lyle Isaacs, Fraser Hof

Chembiochem· January 2022

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Template-Directed Synthesis of Bivalent, Broad-Spectrum Hosts for Neuromuscular Blocking Agents.
Allison J Selinger, Natalie A Cavallin, Anat Yanai, Inanc Birol, Fraser Hof

Angew Chem Int Ed Engl· January 2022

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Polycomb Paralog Chromodomain Inhibitors Active against Both CBX6 and CBX8*.
Natalia Milosevich, Chelsea R Wilson, Tyler M Brown, Aktan Alpsoy, Sijie Wang, Rebecca Hof, Fraser Hof

ChemMedChem· October 2021

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Mechanism of a Disassembly-Driven Sensing System Studied by Stopped-Flow Kinetics.
Cara Gallo, Suma S Thomas, Allison J Selinger, Fraser Hof, Cornelia Bohne

J Org Chem· August 2021

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An easily accessible, lower rim substituted calix[4]arene selectively binds ,-dimethyllysine.
Alok Shaurya, Graham A E Garnett, Melissa J Starke, Mark C Grasdal, Charlotte C Dewar, Fraser Hof

Org Biomol Chem· June 2021

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Host-guest binding in water, salty water, and biofluids: general lessons for synthetic, bio-targeted molecular recognition.
Meagan A Beatty, Fraser Hof

Chem Soc Rev· April 2021

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Pan-specific and partially selective dye-labeled peptidic inhibitors of the polycomb paralog proteins.
Natalia Milosevich, James McFarlane, Michael C Gignac, Janessa Li, Tyler M Brown, Rebecca Hof, Fraser Hof

Bioorg Med Chem· January 2020

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Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor.
Sijie Wang, Kyle E Denton, Kathryn F Hobbs, Tyler Weaver, James M B McFarlane, Fraser Hof

ACS Chem Biol· January 2020

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Parallel Synthesis and Screening of Supramolecular Chemosensors That Achieve Fluorescent Turn-on Detection of Drugs in Saliva.
Meagan A Beatty, Allison J Selinger, YuQi Li, Fraser Hof

J Am Chem Soc· October 2019

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Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists.
Chakravarthi Simhadri, Kevin D Daze, Sarah F Douglas, Natalia Milosevich, Leticia Monjas, Fraser Hof

ChemMedChem· August 2019

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Assessment of Putative PD-1/PD-L1 Inhibitors: Suggestions of an Alternative Mode of Action.
Derek J Blevins, Ronan Hanley, Trevor Bolduc, David A Powell, Michael Gignac, Fraser Hof

ACS Med Chem Lett· August 2019

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Using reversible non-covalent and covalent bonds to create assemblies and equilibrating molecular networks that survive 5 molar urea.
Meagan A Beatty, Aidan T Pye, Alok Shaurya, Belim Kim, Allison J Selinger, Fraser Hof

Org Biomol Chem· February 2019

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Robustness of In Vitro Selection Assays of DNA-Encoded Peptidomimetic Ligands to CBX7 and CBX8.
Kyle E Denton, Sijie Wang, Michael C Gignac, Natalia Milosevich, Fraser Hof

SLAS Discov· June 2018

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Analyte-Driven Disassembly and Turn-On Fluorescent Sensing in Competitive Biological Media.
Meagan A Beatty, Jorge Borges-González, Nicholas J Sinclair, Aidan T Pye, Fraser Hof

J Am Chem Soc· March 2018

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A
Aza-amino acid scanning of chromobox homolog 7 (CBX7) ligands.
Mariam Traoré, Michael Gignac, Ngoc-Duc Doan, Fraser Hof, William D Lubell

J Pept Sci· April 2017

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Structure-Activity Relationships of Cbx7 Inhibitors, Including Selectivity Studies against Other Cbx Proteins.
Chakravarthi Simhadri, Michael C Gignac, Cameron J Anderson, Natalia Milosevich, Aman Dheri, Fraser Hof

ACS Omega· October 2016

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Structural aspects of small-molecule inhibition of methyllysine reader proteins.
Natalia Milosevich, Zoey Warmerdam, Fraser Hof

Future Med Chem· September 2016

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